Rongyuan Zheng
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View article: NSUN2-mediated m5C modification of SOCS3 mRNA modulates macrophage polarization in bladder cancer
NSUN2-mediated m5C modification of SOCS3 mRNA modulates macrophage polarization in bladder cancer Open
Tumor-associated macrophages (TAMs) are pivotal in facilitating the progression of cancer cells. M1 and M2 are two polarization states of TAMs with opposite functions in tumor progression. While the regulatory role of N6-adenosine (m6A) me…
View article: Combined association of triglyceride–glucose index and systemic inflammation index on all-cause and cardiovascular mortality
Combined association of triglyceride–glucose index and systemic inflammation index on all-cause and cardiovascular mortality Open
View article: NSUN2-mediated m5C modification of SOCS3 mRNA modulates macrophage polarization in bladder cancer
NSUN2-mediated m5C modification of SOCS3 mRNA modulates macrophage polarization in bladder cancer Open
Background: Tumor-associated macrophages (TAMs) are pivotal in facilitating the progression of cancer cells. M1 and M2 are two polarization states of TAMs with opposite functions in tumor progression. Recent studies have revealed the regul…
View article: HER2 prognostic values in non-muscle-invasive bladder cancer: a step towards personalized treatment for BCG instillation
HER2 prognostic values in non-muscle-invasive bladder cancer: a step towards personalized treatment for BCG instillation Open
This comment discusses the findings of a study on the prognostic significance of HER2 expression in high-risk non-muscle-invasive bladder cancer (NMIBC) patients treated with Bacillus Calmette-Guérin (BCG) therapy. The study highlights tha…
View article: PAI1 regulating CHRNA1 contributes to primary focal hyperhidrosis: Clinical and experimental studies
PAI1 regulating CHRNA1 contributes to primary focal hyperhidrosis: Clinical and experimental studies Open
View article: Neutrophil-to-lymphocyte ratio predicts a poor prognosis for penile cancer with an immunosuppressive tumor microenvironment
Neutrophil-to-lymphocyte ratio predicts a poor prognosis for penile cancer with an immunosuppressive tumor microenvironment Open
Background Chronic inflammation related to poor genital hygiene is a well-recognized pathogenic trigger for penile cancer (PC). The neutrophil-to-lymphocyte ratio (NLR) is a simple, reproducible systemic inflammatory marker and has been re…
View article: Advances in non-invasive neuromodulation techniques for geriatric depression: A comprehensive review
Advances in non-invasive neuromodulation techniques for geriatric depression: A comprehensive review Open
The gradual aging of the global population is increasing the prevalence of geriatric depression, a severe mental disorder that imposes a significant burden on individuals and society. Conventional treatments such as pharmacotherapy and psy…
View article: The interaction between triglyceride-glucose index and visceral adiposity in cardiovascular disease risk: findings from a nationwide Chinese cohort
The interaction between triglyceride-glucose index and visceral adiposity in cardiovascular disease risk: findings from a nationwide Chinese cohort Open
View article: Effects of adding adjuvants to propofol on the post-anesthesia cognitive function in patients undergoing gastroscopy/colonoscopy: a systematic review and meta-analysis
Effects of adding adjuvants to propofol on the post-anesthesia cognitive function in patients undergoing gastroscopy/colonoscopy: a systematic review and meta-analysis Open
This study aimed to elucidate the effects of propofol plus adjuvants on postoperative cognitive dysfunction (POCD) and patient satisfaction. Studies published up to September 2023 on the Chinese National Knowledge Infrastructure (CNKI), Wa…
View article: Effects of adding adjuvants to propofol on the post-anesthesia cognitive function in patients undergoing gastroscopy/colonoscopy: A systematic review and meta-analysis
Effects of adding adjuvants to propofol on the post-anesthesia cognitive function in patients undergoing gastroscopy/colonoscopy: A systematic review and meta-analysis Open
Review question / Objective How about the effects of adding adjuvants to propofol on the post-anesthesia cognitive function for patients with gastroscopy/colonoscopy. C o n d i t i o n b e i n g s t u d i e d P a t i e n t s w i t h gastro…
View article: External validation of the AntiEpileptic Drug Monitoring in PREgnancy (EMPiRE) model for predicting seizures in pregnant women with epilepsy
External validation of the AntiEpileptic Drug Monitoring in PREgnancy (EMPiRE) model for predicting seizures in pregnant women with epilepsy Open
View article: Supplementary Material for: Development and validation of a nomogram for renal survival prediction in patients with autosomal dominant polycystic kidney disease
Supplementary Material for: Development and validation of a nomogram for renal survival prediction in patients with autosomal dominant polycystic kidney disease Open
Introduction：Due to the wide variation in the prognosis of autosomal dominant polycystic kidney disease (ADPKD), prediction of risk of renal survival in ADPKD patients is a tough challenge. We aimed to establish a nomogram for the predicti…
View article: Eslicarbazepine acetate add-on therapy for drug-resistant focal epilepsy
Eslicarbazepine acetate add-on therapy for drug-resistant focal epilepsy Open
ESL reduces seizure frequency when used as an add-on treatment for adults with drug-resistant focal epilepsy. The trials included in this review were of short-term duration. In addition, this update found that ESL may reduce seizure freque…
View article: Validation of Predictive Models for Autoimmune Encephalitis-Related Antibodies to Cell-Surface Proteins Expressed in Neurons: A Retrospective Study Based in a Hospital
Validation of Predictive Models for Autoimmune Encephalitis-Related Antibodies to Cell-Surface Proteins Expressed in Neurons: A Retrospective Study Based in a Hospital Open
Objective: Autoimmune encephalitis (AE) is a severe but treatable autoimmune disorder that is diagnosed by antibody (Ab) testing. However, it is unrealistic to obtain an early diagnosis in some areas since the Ab status cannot be immediate…
View article: Supplementary Material for: Associations of Body Mass Index-Metabolic Phenotypes with Cognitive Decline in Parkinson’s Disease
Supplementary Material for: Associations of Body Mass Index-Metabolic Phenotypes with Cognitive Decline in Parkinson’s Disease Open
Background: Growing evidence suggests important effects of body mass index (BMI) and metabolic status on neurodegenerative diseases. However, the roles of BMI and metabolic status on cognitive outcomes in Parkinson’s disease …
View article: Patient Preference for Antiepileptic Drugs Treatment in China: Evidence From the Discrete Choice Experiment
Patient Preference for Antiepileptic Drugs Treatment in China: Evidence From the Discrete Choice Experiment Open
Objective: Explore Chinese patients' risk-benefit preferences and willingness-to-pay (WTP) for antiepileptic drugs (AEDs) treatment through the discrete choice experiment (DCE). Method: Six attributes including the efficacy of AEDs, advers…
View article: Endometriosis-related spontaneous haemoperitoneum in pregnancy - case report and literature review
Endometriosis-related spontaneous haemoperitoneum in pregnancy - case report and literature review Open
Spontaneous haemoperitoneum in pregnancy (SHiP) is a rare disease that is associated with adverse pregnancy outcome. The authors present a case of a 35-year-old pregnant woman who developed spontaneous haemoperitoneum at 33 weeks of gestat…
View article: Adverse drug reactions associated with six commonly used antiepileptic drugs in southern China from 2003 to 2015
Adverse drug reactions associated with six commonly used antiepileptic drugs in southern China from 2003 to 2015 Open
View article: Substitution has better efficacy than add-on therapy for patients with focal epilepsy after their first antiepileptic drug treatments fail
Substitution has better efficacy than add-on therapy for patients with focal epilepsy after their first antiepileptic drug treatments fail Open
View article: Garcin syndrome caused by parotid gland adenoid cystic carcinoma
Garcin syndrome caused by parotid gland adenoid cystic carcinoma Open
To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome.
View article: Eslicarbazepine acetate add-on for drug-resistant focal epilepsy
Eslicarbazepine acetate add-on for drug-resistant focal epilepsy Open
Background This is an updated version of the Cochrane Review published in the Cochrane Library 2011, Issue 12. The majority of people with epilepsy have a good prognosis, but up to 30% of people continue to have seizures despite several re…
View article: Comparative Long-Term Effectiveness of a Monotherapy with Five Antiepileptic Drugs for Focal Epilepsy in Adult Patients: A Prospective Cohort Study
Comparative Long-Term Effectiveness of a Monotherapy with Five Antiepileptic Drugs for Focal Epilepsy in Adult Patients: A Prospective Cohort Study Open
LTG was the best, OXC was better than VPA only, while VPA was the worst. The others were equivalent for comparisons between five AEDs regarding the long-term treatment outcomes of monotherapy for adult patients with focal epilepsy in a cli…