2024-01-19
Single-cell RNA sequencing reveals cellular senescence functions as a prognostic and therapeutic indicator in meningiomas
2024-01-19 • Rongzeng Guo, Changxiang Yan, Xiaojun Fu
Abstract Meningiomas rank among the most prevalent solid tumors in the human central nervous system, exhibiting a wide spectrum of prognoses, with particularly challenging outcomes in cases of malignant meningiomas. Cellular senescence (CS) is recognized as a significant prognostic and therapeutic indicator in numerous types of tumors. However, the characterization of CS in meningiomas has remained largely unexplored. This study delves into cellular senescence (CS) as a prognostic and therapeutic factor in meningi…