Ronit Gavrieli
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View article: Neutrophil reactive oxygen formation, bacterial infections and mortality in malnourished hemodialysis patients: Evaluation of clinical outcomes
Neutrophil reactive oxygen formation, bacterial infections and mortality in malnourished hemodialysis patients: Evaluation of clinical outcomes Open
Introduction Patients with end stage kidney disease undergoing maintenance hemodialysis (MHD) are prone to malnutrition and infections. Objective The objective of this study was to evaluate the effect of polymorphonuclear (PMN) cell dysfun…
View article: Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects
Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects Open
The T cell receptor (TCR) signaling pathway is an ensemble of numerous proteins that are crucial for an adequate immune response. Disruption of any protein involved in this pathway leads to severe immunodeficiency and unfavorable clinical …
View article: Late diagnosis of chronic granulomatous disease
Late diagnosis of chronic granulomatous disease Open
Summary Modern era advancements in medical care, with improved treatment of infections, can result in delayed diagnosis of congenital immunodeficiencies. In this study we present a retrospective cohort of 16 patients diagnosed with Chronic…
View article: Chronic granulomatous disease: Clinical, functional, molecular, and genetic studies. The Israeli experience with 84 patients
Chronic granulomatous disease: Clinical, functional, molecular, and genetic studies. The Israeli experience with 84 patients Open
Chronic granulomatous disease (CGD) is an innate immunodeficiency with a genetic defect of the nicotinamide adenosine dinucleotide phosphate, reduced, oxidase components. This leads to decreased reactive oxygen species (ROS) production, wh…