Rosa Capozzo
YOU?
Author Swipe
View article: Natural Language Processing differentiates between Italian individuals with Nonfluent/Agrammatic from Logopenic variants of PPA
Natural Language Processing differentiates between Italian individuals with Nonfluent/Agrammatic from Logopenic variants of PPA Open
Background Differentiating between logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary Progressive Aphasia relies on expert evaluations of speech and language production. The dichotomy fluency/non‐fluency is not enough …
View article: Role of plasma phosphorylated neurofilament heavy chain (pNfH) in amyotrophic lateral sclerosis
Role of plasma phosphorylated neurofilament heavy chain (pNfH) in amyotrophic lateral sclerosis Open
The phosphorylated neurofilament heavy chain (pNfH) is a promising biomarker in amyotrophic lateral sclerosis (ALS). We examined plasma pNfH concentrations in order to corroborate its role as a diagnostic and prognostic biomarker in ALS. I…
View article: The Role of Age on Beta-Amyloid1–42 Plasma Levels in Healthy Subjects
The Role of Age on Beta-Amyloid1–42 Plasma Levels in Healthy Subjects Open
Beta-amyloid (Aβ) plaques have been observed in the brain of healthy elderlies with frequencies strongly influenced by age. The aim of the study is to evaluate the role of age and other biochemical and hematological parameters on Aβ 1–42 p…
View article: Reduction of Sniff Nasal Inspiratory Pressure (SNIP) as an Early Indicator of the Need of Enteral Nutrition in Patients with Amyotrophic Lateral Sclerosis
Reduction of Sniff Nasal Inspiratory Pressure (SNIP) as an Early Indicator of the Need of Enteral Nutrition in Patients with Amyotrophic Lateral Sclerosis Open
Percutaneous endoscopic gastrostomy (PEG) is the standard procedure for feeding severely dysphagic patients with amyotrophic lateral sclerosis (ALS). It is associated with prolonged survival and improvement in quality of life. Nasal inspir…
View article: Exploring dementia and neuronal ceroid lipofuscinosis genes in 100 FTD-like patients from 6 towns and rural villages on the Adriatic Sea cost of Apulia
Exploring dementia and neuronal ceroid lipofuscinosis genes in 100 FTD-like patients from 6 towns and rural villages on the Adriatic Sea cost of Apulia Open
Frontotemporal dementia (FTD) refers to a complex spectrum of clinically and genetically heterogeneous disorders. Although fully penetrant mutations in several genes have been identified and can explain the pathogenic mechanisms underlying…
View article: Brain Structural Covariance Networks in Behavioral Variant of Frontotemporal Dementia
Brain Structural Covariance Networks in Behavioral Variant of Frontotemporal Dementia Open
Recent research on behavioral variant frontotemporal dementia (bvFTD) has shown that personality changes and executive dysfunctions are accompanied by a disease-specific anatomical pattern of cortical and subcortical atrophy. We investigat…
View article: The Italian Version of the Test Your Memory (TYM-I): A Tool to Detect Mild Cognitive Impairment in the Clinical Setting
The Italian Version of the Test Your Memory (TYM-I): A Tool to Detect Mild Cognitive Impairment in the Clinical Setting Open
The Test Your Memory (TYM) is a brief self-administered, cognitive screening test, currently used in several settings. It requires minimal administrator supervision and the computation of the final test score takes approximately 2 min. We …
View article: Age‐Related Central Auditory Processing Disorder, MCI, and Dementia in an Older Population of Southern Italy
Age‐Related Central Auditory Processing Disorder, MCI, and Dementia in an Older Population of Southern Italy Open
Objective We explored the associations of age‐related central auditory processing disorder (CAPD) with mild cognitive impairment (MCI) and dementia in an older population‐based cohort in Apulia, Southern Italy (GreatAGE Study). Study Desig…
View article: The Age-Related Central Auditory Processing Disorder: Silent Impairment of the Cognitive Ear
The Age-Related Central Auditory Processing Disorder: Silent Impairment of the Cognitive Ear Open
Age-related hearing loss (ARHL), also called presbycusis, is a progressive disorder affecting hearing functions and among the elderly has been recognized as the third most frequent condition. Among ARHL components, the age-related central …
View article: <p>Early pathological gambling in co-occurrence with semantic variant primary progressive aphasia: a case report</p>
Early pathological gambling in co-occurrence with semantic variant primary progressive aphasia: a case report Open
We have comprehensively documented a case of semantic variant of primary progressive aphasia (sv-PPA) presenting with early-onset pathological gambling (PG). While a growing number of studies have shown the presence of behavioral alteratio…
View article: Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies
Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies Open
We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subj…
View article: Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline
Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline Open
Among metabolic syndrome components, the effects of higher plasma glucose levels on cognitive decline (CD) have been considered in few studies. We evaluated the associations among midlife glycemia, total cholesterol, high-density lipoprote…
View article: Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy
Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy Open
Introduction We investigated the clinical differences between familial and sporadic frontotemporal dementia (FTD), screening for mutations in known FTD genes. Methods We diagnosed 22 affected individuals belonging to eight families and 43 …
View article: Erratum: The Prevalence of Peripheral and Central Hearing Impairment and Its Relation to Cognition in Older Adults
Erratum: The Prevalence of Peripheral and Central Hearing Impairment and Its Relation to Cognition in Older Adults Open
Age-related hearing loss (ARHL) and dementia are two highly prevalent conditions in the adult population. Recent studies have suggested that hearing loss is independently associated with poorer cognitive functioning. The aim of this study …
View article: A Novel Splice-Acceptor Site Mutation in GRN (c.709-2 A>T) Causes Frontotemporal Dementia Spectrum in a Large Family from Southern Italy
A Novel Splice-Acceptor Site Mutation in GRN (c.709-2 A>T) Causes Frontotemporal Dementia Spectrum in a Large Family from Southern Italy Open
Heterozygous loss of function mutations in granulin represent a significant cause of frontotemporal lobar degeneration with ubiquitin and TDP-43 inclusions (FTLD-TDP). We report a novel GRN splice site mutation (c.709-2 A>T), segregating w…
View article: Examination of level of knowledge in Italian general practitioners attending an education session on diagnosis and management of the early stage of Alzheimer's disease: pass or fail?
Examination of level of knowledge in Italian general practitioners attending an education session on diagnosis and management of the early stage of Alzheimer's disease: pass or fail? Open
Background: We detected the general level of knowledge about the early diagnosis of Alzheimer's disease (AD) and subsequent care in general practitioners (GPs) from Southern Italy. We explored also the GP perception about their knowledge a…
View article: Tau aggregation inhibitors: the future of Alzheimer’s pharmacotherapy?
Tau aggregation inhibitors: the future of Alzheimer’s pharmacotherapy? Open
Non disponibile
View article: Frontal assessment battery for detecting executive dysfunction in amyotrophic lateral sclerosis without dementia: a retrospective observational study
Frontal assessment battery for detecting executive dysfunction in amyotrophic lateral sclerosis without dementia: a retrospective observational study Open
Objective The frontal assessment battery (FAB) is a quick and reliable method of screening to evaluate frontal lobe dysfunction in amyotrophic lateral sclerosis (ALS). However, previous studies were generally conducted on small samples rep…
View article: Age-related hearing impairment and frailty in Alzheimer's disease: interconnected associations and mechanisms
Age-related hearing impairment and frailty in Alzheimer's disease: interconnected associations and mechanisms Open
Among potentially modifiable age-related conditions linked to dementia, Alzheimer’s disease (AD),and late-life cognitive disorders, age-related hearing impairment (ARHI) or resbycusis is themost widely diffused sensory disorder and one of …