Rosa Cortese
YOU?
Author Swipe
View article: Applying the Supporting Features for MOGAD Diagnosis to Patients With Multiple Sclerosis
Applying the Supporting Features for MOGAD Diagnosis to Patients With Multiple Sclerosis Open
Although the MOGAD supporting features can be met in one-fourth of patients at MS/CIS presentation, the risk of misdiagnosis in similar unselected cohorts remains low. Future refinements of the MOGAD supporting features should take into ac…
View article: Clinically Relevant Patterns of Co‐Fluctuating Structure and Function in Multiple Sclerosis
Clinically Relevant Patterns of Co‐Fluctuating Structure and Function in Multiple Sclerosis Open
Background While structural and functional connectivity changes in multiple sclerosis (MS) are well documented, their complex interplay remains poorly understood. This study identifies co‐fluctuating patterns of structural and functional c…
View article: Multi-Domain Brain Vessel Segmentation Through Feature Disentanglement
Multi-Domain Brain Vessel Segmentation Through Feature Disentanglement Open
The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive unde…
View article: Deep Learning Modeling to Differentiate Multiple Sclerosis From MOG Antibody–Associated Disease
Deep Learning Modeling to Differentiate Multiple Sclerosis From MOG Antibody–Associated Disease Open
This study provides Class III evidence that both a clinical/MRI algorithm and an MRI-based DL model accurately distinguish RRMS from MOGAD.
View article: Real-Life Evaluation of the MOGAD Diagnostic Criteria
Real-Life Evaluation of the MOGAD Diagnostic Criteria Open
MOGAD criteria demonstrate a good performance across different centers; however, controversial cases might benefit from collegial discussion and reassessment of MOGAD criteria during the follow-up. Main challenges include availability of p…
View article: It Is Time to See MOGAD From a Different Perspective Than Multiple Sclerosis
It Is Time to See MOGAD From a Different Perspective Than Multiple Sclerosis Open
View article: Clinical and MRI features contributing to the clinico-radiological dissociation in a large cohort of people with multiple sclerosis
Clinical and MRI features contributing to the clinico-radiological dissociation in a large cohort of people with multiple sclerosis Open
View article: Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy
Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy Open
Objectives We aim to investigate cognitive phenotype distribution and MRI correlates across pediatric‐, elderly‐, and adult‐onset MS patients as a function of disease duration. Methods In this cross‐sectional study, we enrolled 1262 MS pat…
View article: More Than the Sum of Its Parts: Disrupted Core Periphery of Multiplex Brain Networks in Multiple Sclerosis
More Than the Sum of Its Parts: Disrupted Core Periphery of Multiplex Brain Networks in Multiple Sclerosis Open
Disruptions to brain networks, measured using structural (sMRI), diffusion (dMRI), or functional (fMRI) MRI, have been shown in people with multiple sclerosis (PwMS), highlighting the relevance of regions in the core of the connectome but …
View article: Disentangling Neurodegeneration From Aging in Multiple Sclerosis Using Deep Learning
Disentangling Neurodegeneration From Aging in Multiple Sclerosis Using Deep Learning Open
The brain-predicted DD gap is sensitive to MS-related lesions and brain atrophy, adds to the brain-age paradigm in explaining physical disability both cross-sectionally and longitudinally, and may be used as an MS-specific biomarker of dis…
View article: Hippocampal atrophy and white matter lesions characteristics can predict evolution to dementia in patients with vascular mild cognitive impairment
Hippocampal atrophy and white matter lesions characteristics can predict evolution to dementia in patients with vascular mild cognitive impairment Open
HV and WMLs are significant predictors of progression from VMCI to VaD. Lower HV correlate with worse cognitive performance on RAVLT and MMSE tests.
View article: Evaluation of cervical spinal cord atrophy using a modified SIENA approach
Evaluation of cervical spinal cord atrophy using a modified SIENA approach Open
Spinal cord (SC) atrophy obtained from structural magnetic resonance imaging has gained relevance as an indicator of neurodegeneration in various neurological disorders. The common method to assess SC atrophy is by comparing numerical diff…
View article: Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody‐associated Disease, Aquaporin‐4 Antibody‐Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis
Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody‐associated Disease, Aquaporin‐4 Antibody‐Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis Open
Objective To evaluate: (1) the distribution of gray matter (GM) atrophy in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), aquaporin‐4 antibody‐positive neuromyelitis optica spectrum disorder (AQP4+NMOSD), and rela…
View article: Regional hippocampal atrophy reflects memory impairment in patients with early relapsing remitting multiple sclerosis
Regional hippocampal atrophy reflects memory impairment in patients with early relapsing remitting multiple sclerosis Open
Background Research work has shown that hippocampal subfields are atrophic to varying extents in multiple sclerosis (MS) patients. However, studies examining the functional implications of subfield-specific hippocampal damage in early MS a…
View article: Optic chiasm involvement in multiple sclerosis, aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein–associated disease
Optic chiasm involvement in multiple sclerosis, aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein–associated disease Open
Background: Optic neuritis (ON) is a common feature of inflammatory demyelinating diseases (IDDs) such as multiple sclerosis (MS), aquaporin 4-antibody neuromyelitis optica spectrum disorder (AQP4 + NMOSD) and myelin oligodendrocyte glycop…
View article: Magnetic Resonance Imaging Evidence Supporting the Efficacy of Cladribine Tablets in the Treatment of Relapsing-Remitting Multiple Sclerosis
Magnetic Resonance Imaging Evidence Supporting the Efficacy of Cladribine Tablets in the Treatment of Relapsing-Remitting Multiple Sclerosis Open
View article: Disentangling neurodegeneration from ageing in multiple sclerosis: the brain-predicted disease duration gap
Disentangling neurodegeneration from ageing in multiple sclerosis: the brain-predicted disease duration gap Open
Disentangling brain ageing from disease-related neurodegeneration in patients with multiple sclerosis (PwMS) is increasingly topical. The brain-age paradigm offers a window into this problem but may miss disease-specific effects. Here, we …
View article: Federated Multi-centric Image Segmentation with Uneven Label Distribution
Federated Multi-centric Image Segmentation with Uneven Label Distribution Open
View article: Diagnostic Performance of Cortical Lesions and the Central Vein Sign in Multiple Sclerosis
Diagnostic Performance of Cortical Lesions and the Central Vein Sign in Multiple Sclerosis Open
Importance Multiple sclerosis (MS) misdiagnosis remains an important issue in clinical practice. Objective To quantify the performance of cortical lesions (CLs) and central vein sign (CVS) in distinguishing MS from other conditions showing…
View article: <i>FOLR1</i> Gene Variation With Adult-Onset Cerebral Folate Deficiency and Stable Clinical and MRI Features up to 2 Years
<i>FOLR1</i> Gene Variation With Adult-Onset Cerebral Folate Deficiency and Stable Clinical and MRI Features up to 2 Years Open
Scientific evidence supports the deleterious effect of c.45G>T and c.493+2T>C variations on the folate receptor-α (FRα) protein structure and function. The weakness of the expression and function of FRα without elimination of its function …
View article: A2V: A Semi-Supervised Domain Adaptation Framework for Brain Vessel Segmentation via Two-Phase Training Angiography-to-Venography Translation
A2V: A Semi-Supervised Domain Adaptation Framework for Brain Vessel Segmentation via Two-Phase Training Angiography-to-Venography Translation Open
We present a semi-supervised domain adaptation framework for brain vessel segmentation from different image modalities. Existing state-of-the-art methods focus on a single modality, despite the wide range of available cerebrovascular imagi…
View article: Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients With Central Nervous System Demyelination
Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients With Central Nervous System Demyelination Open
Importance Differential diagnosis of patients with seronegative demyelinating central nervous system (CNS) disease is challenging. In this regard, evidence suggests that immunoglobulin (Ig) A plays a role in the pathogenesis of different a…
View article: <scp>BIANCA‐MS</scp>: An optimized tool for automated multiple sclerosis lesion segmentation
<span>BIANCA‐MS</span>: An optimized tool for automated multiple sclerosis lesion segmentation Open
In this work we present BIANCA‐MS, a novel tool for brain white matter lesion segmentation in multiple sclerosis (MS), able to generalize across both the wide spectrum of MRI acquisition protocols and the heterogeneity of manually labeled …
View article: Correction to: Resting-state functional MRI in multicenter studies on multiple sclerosis: a report on raw data quality and functional connectivity features from the Italian Neuroimaging Network Initiative
Correction to: Resting-state functional MRI in multicenter studies on multiple sclerosis: a report on raw data quality and functional connectivity features from the Italian Neuroimaging Network Initiative Open
View article: Pregnancy and antibody-mediated CNS disorders: What do we know and what should we know?
Pregnancy and antibody-mediated CNS disorders: What do we know and what should we know? Open
Antibody-mediated central nervous system (CNS) disorders including those associated with aquaporin-4 or myelin oligodendrocyte glycoprotein IgG and autoimmune encephalitis often affect women of childbearing age. Pathogenic antibodies of th…
View article: More than the sum of its parts: disrupted core-periphery of multiplex networks in multiple sclerosis
More than the sum of its parts: disrupted core-periphery of multiplex networks in multiple sclerosis Open
Disruptions to brain networks, measured using either structural (sMRI), diffusion (dMRI), or resting-state functional (rs-fMRI) MRI, have been shown in people with multiple sclerosis (PwMS), highlighting the importance of damage to regions…
View article: Clinical and MRI measures to identify non-acute MOG-antibody disease in adults
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults Open
MRI and clinical features of myelin oligodendrocyte glycoprotein (MOG)-antibody disease may overlap with those of other inflammatory demyelinating conditions posing diagnostic challenges, especially in non-acute phases and when serologic t…
View article: Resting-state functional MRI in multicenter studies on multiple sclerosis: a report on raw data quality and functional connectivity features from the Italian Neuroimaging Network Initiative
Resting-state functional MRI in multicenter studies on multiple sclerosis: a report on raw data quality and functional connectivity features from the Italian Neuroimaging Network Initiative Open
View article: Vessel-CAPTCHA: An efficient learning framework for vessel annotation and segmentation
Vessel-CAPTCHA: An efficient learning framework for vessel annotation and segmentation Open
View article: Prediction of the information processing speed performance in multiple sclerosis using a machine learning approach in a large multicenter magnetic resonance imaging data set
Prediction of the information processing speed performance in multiple sclerosis using a machine learning approach in a large multicenter magnetic resonance imaging data set Open
Many patients with multiple sclerosis (MS) experience information processing speed (IPS) deficits, and the Symbol Digit Modalities Test (SDMT) has been recommended as a valid screening test. Magnetic resonance imaging (MRI) has markedly im…