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View article: Dosimetric study on radioembolization with 166Ho poly L-lactic acid microspheres: dead time effects on prediction power
Dosimetric study on radioembolization with 166Ho poly L-lactic acid microspheres: dead time effects on prediction power Open
View article: Safety and efficacy of Holmium-166 selective internal radiotherapy of primary and secondary liver cancer confirmed by real-world data
Safety and efficacy of Holmium-166 selective internal radiotherapy of primary and secondary liver cancer confirmed by real-world data Open
Purpose Holmium-166 has emerged as a promising option for selective internal radiotherapy (SIRT) for hepatic malignancies, but data on routine clinical use are lacking. The purpose of this study was to describe the safety and effectiveness…
View article: Lymphoid Organs’ Metabolism and its Role in Predicting the Outcomes of Patients with Malignant Melanoma Treated with Immunotherapy – an Exploratory Study
Lymphoid Organs’ Metabolism and its Role in Predicting the Outcomes of Patients with Malignant Melanoma Treated with Immunotherapy – an Exploratory Study Open
Background. This study aimed to evaluate the changes in 2-[18F]-FDG PET/CT parameters of lymphoid organs and their association with clinical outcomes in melanoma patients undergoing immunotherapy. Materials and methods. Ninety-two consecut…
View article: Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol
Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol Open
View article: Prognostic value of [18F]-FDG PET/CT in patients with meta-static breast cancer treated with cyclin-dependent inhibitors
Prognostic value of [18F]-FDG PET/CT in patients with meta-static breast cancer treated with cyclin-dependent inhibitors Open
Objective The addition of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) to endocrine therapy impressively improved the outcome of patients with hormone receptor-positive metastatic breast cancer. Despite their great efficacy, not all pa…
View article: A real-time system to report abnormal events involving staff in a nuclear medicine therapy unit
A real-time system to report abnormal events involving staff in a nuclear medicine therapy unit Open
A system for internal and voluntary reporting of abnormal events in a Nuclear Medicine Therapy Unit is described. This system is based on the Internet of Things and is composed of an application for mobile devices and a wireless network of…
View article: ITA-IMMUNO-PET: The Role of [18F]FDG PET/CT for Assessing Response to Immunotherapy in Patients with Some Solid Tumors
ITA-IMMUNO-PET: The Role of [18F]FDG PET/CT for Assessing Response to Immunotherapy in Patients with Some Solid Tumors Open
AIM: To examine the role of [18F]FDG PET/CT for assessing response to immunotherapy in patients with some solid tumors. METHODS: Data recorded in a multicenter (n = 17), retrospective database between March and November 2021 were analyzed.…
View article: Prognostic Value of Pre-Treatment [18F]FDG PET/CT Texture Analysis in Undifferentiated Soft-Tissue Sarcoma
Prognostic Value of Pre-Treatment [18F]FDG PET/CT Texture Analysis in Undifferentiated Soft-Tissue Sarcoma Open
Background: Undifferentiated soft-tissue sarcomas (USTS) are one of the most common sarcoma histotypes in adults. The standard of care is surgical excision plus adjuvant radiotherapy, while the use of perioperative chemotherapy is still co…
View article: Ita-immuno-pet: the Role of Fdg Pet/ct for Assessing Response to Immunotherapy
Ita-immuno-pet: the Role of Fdg Pet/ct for Assessing Response to Immunotherapy Open
AIM: to examine the role of FDG PET/CT for assessing response to immunotherapy in patients with solid tumors. MATERIALS AND METHODS: data recorded in a multicenter (n=17), retrospective database between March and November 2021 were analyze…
View article: A Workflow for Dosimetry of 90Y Radioembolization Based on Quantitative 99mTc-MAA SPECT/CT Imaging and a 3D-Printed Phantom
A Workflow for Dosimetry of 90Y Radioembolization Based on Quantitative 99mTc-MAA SPECT/CT Imaging and a 3D-Printed Phantom Open
At a time of increasing evidence for dose-effect relationships in radioembolization (RE) with 90Y-microspheres, the general consensus is that there is an urgent need for accurate treatment planning and dose assessment in patients undergoin…
View article: 18F-FDG PET/CT in the clinical-diagnostic workup of patients treated with immunotherapy: when and how?
18F-FDG PET/CT in the clinical-diagnostic workup of patients treated with immunotherapy: when and how? Open
View article: Correction to: Prognostic value of total metabolic tumour volume and therapy-response assessment by [18F]FDG PET/CT in patients with metastatic melanoma treated with BRAF/MEK inhibitors
Correction to: Prognostic value of total metabolic tumour volume and therapy-response assessment by [18F]FDG PET/CT in patients with metastatic melanoma treated with BRAF/MEK inhibitors Open
View article: Bone density and genomic analysis unfold cold adaptation mechanisms of ancient inhabitants of Tierra del Fuego
Bone density and genomic analysis unfold cold adaptation mechanisms of ancient inhabitants of Tierra del Fuego Open
View article: A Prospective Study Assessing the Post-Prostatectomy Detection Rate of a Presumed Local Failure at mpMR with Either 64CuCl2 or 64CuPSMA PET/CT
A Prospective Study Assessing the Post-Prostatectomy Detection Rate of a Presumed Local Failure at mpMR with Either 64CuCl2 or 64CuPSMA PET/CT Open
Background: We aimed assess the detection rate (DR) of positron emission tomography/computed tomography with two novel tracers in patients referred for salvage radiotherapy (sRT) with a presumed local recurrence at multiparametric magnetic…
View article: The role of dosimetry and biological effects in metastatic castration–resistant prostate cancer (mCRPC) patients treated with 223Ra: first in human study
The role of dosimetry and biological effects in metastatic castration–resistant prostate cancer (mCRPC) patients treated with 223Ra: first in human study Open
Background 223 Ra is currently used for treatment of metastatic castration resistant prostate cancer patients (mCRPC) bone metastases with fixed standard activity. Individualized treatments, based on adsorbed dose (AD) in target and non-ta…
View article: CT radiomics-based machine learning classification of atypical cartilaginous tumours and appendicular chondrosarcomas
CT radiomics-based machine learning classification of atypical cartilaginous tumours and appendicular chondrosarcomas Open
View article: Bone Density and Genomic Analysis Unfold Cold Adaptation Mechanisms of Extinct Inhabitants of Tierra Del Fuego
Bone Density and Genomic Analysis Unfold Cold Adaptation Mechanisms of Extinct Inhabitants of Tierra Del Fuego Open
The Fuegians, extinct inhabitants of Tierra del Fuego, were an exemplary case of a cold-adapted population capable of living in extreme weather conditions without any adequate clothing, however the mechanisms of their extraordinary resista…
View article: Prevalence of interstitial pneumonia suggestive of COVID-19 at 18F-FDG PET/CT in oncological asymptomatic patients in a high prevalence country during pandemic period: a national multi-centric retrospective study
Prevalence of interstitial pneumonia suggestive of COVID-19 at 18F-FDG PET/CT in oncological asymptomatic patients in a high prevalence country during pandemic period: a national multi-centric retrospective study Open
View article: Diagnostic and Clinical Impact of 18F-FDG PET/CT in Staging and Restaging Soft-Tissue Sarcomas of the Extremities and Trunk: Mono-Institutional Retrospective Study of a Sarcoma Referral Center
Diagnostic and Clinical Impact of 18F-FDG PET/CT in Staging and Restaging Soft-Tissue Sarcomas of the Extremities and Trunk: Mono-Institutional Retrospective Study of a Sarcoma Referral Center Open
Background: Soft-tissue sarcomas (STS) represent a wide heterogeneous class of rare tumors. The exact role 18F-fluorodeoxyglucose positron emission/computed tomography (18F-FDG PET/CT) in the evaluation of STS is not well established. The …
View article: Correlation between histogram-based DCE-MRI parameters and 18F-FDG PET values in oropharyngeal squamous cell carcinoma: Evaluation in primary tumors and metastatic nodes
Correlation between histogram-based DCE-MRI parameters and 18F-FDG PET values in oropharyngeal squamous cell carcinoma: Evaluation in primary tumors and metastatic nodes Open
Evident relationships emerged between DCE-MRI and 18F-FDG PET parameters in OPSCC LNs, while no association was found in PTs. The complex relationships between perfusion and metabolic biomarkers should be interpreted separately for primary…
View article: Comparison 18F-FDG-PET/CT criteria for prediction of therapy response and clinical outcome in patients with metastatic melanoma treated with ipilimumab and PD-1 inhibitors
Comparison 18F-FDG-PET/CT criteria for prediction of therapy response and clinical outcome in patients with metastatic melanoma treated with ipilimumab and PD-1 inhibitors Open
View article: Delivery of selective internal radiation therapy complicated by variant hepatic vascular anatomy
Delivery of selective internal radiation therapy complicated by variant hepatic vascular anatomy Open
View article: The predictive value of 18F-FDG PET/CT after ipilimumab for treatment response evaluation in metastatic melanoma patients
The predictive value of 18F-FDG PET/CT after ipilimumab for treatment response evaluation in metastatic melanoma patients Open
Background: In previous reports it has been demonstrated that the 18F-FDG PET/CT performs better than contrast-enhanced CT in assessing the response to immunotherapy treatment in patients affected by metastatic melanomas. Aim of the presen…
View article: [OA168] Biological effects evaluation in peripheral blood lymphocytes from patients undergoing radium-223 chloride (223RaCl2) therapy
[OA168] Biological effects evaluation in peripheral blood lymphocytes from patients undergoing radium-223 chloride (223RaCl2) therapy Open
View article: [OA165] Optimization of quantitative 99MTC-MAA SPECT/CT imaging for 90Y RADIOEMBOLIZATION: A 3D-printed phantom study
[OA165] Optimization of quantitative 99MTC-MAA SPECT/CT imaging for 90Y RADIOEMBOLIZATION: A 3D-printed phantom study Open
View article: Radioembolisation in patients with hepatocellular carcinoma that have previously received liver-directed therapies
Radioembolisation in patients with hepatocellular carcinoma that have previously received liver-directed therapies Open
View article: Trans-arterial radio-embolization: a new chance for patients with hepatocellular cancer to access liver transplantation, a world review
Trans-arterial radio-embolization: a new chance for patients with hepatocellular cancer to access liver transplantation, a world review Open
Liver transplantation (LT) for hepatocellular carcinoma (HCC) within the Milan criteria (MC) is nowadays a curative procedure. Yttrium-90 microspheres radioembolization (Y90-RE) has shown to be an effective and safe treatment of primary li…
View article: Hepatocellular carcinoma with macrovascular invasion treated with yttrium-90 radioembolization prior to transplantation
Hepatocellular carcinoma with macrovascular invasion treated with yttrium-90 radioembolization prior to transplantation Open
We reported a short series of patients transplanted after Y90-RE in patients with BCLC stage C. In our experience we achieved acceptable overall and disease-free survival. Eventually, Y90-RE seems to have a place in the downstaging strateg…
View article: Long term efficacy and safety of Fludarabine, Cyclophosphamide and Rituximab regimen followed by 90Y-ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma
Long term efficacy and safety of Fludarabine, Cyclophosphamide and Rituximab regimen followed by 90Y-ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma Open