Rosalyn C. Zimmermann
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View article: Integrative Structural Modeling of Intrinsically Disordered Regions in a Human HDAC2 Chromatin Remodeling Complex
Integrative Structural Modeling of Intrinsically Disordered Regions in a Human HDAC2 Chromatin Remodeling Complex Open
Intrinsically disordered regions (IDRs) and intrinsically disordered proteins (IDPs) play pivotal roles in cellular signaling, molecular recognition, and the regulation of various biological processes. These flexible and conformationally d…
View article: Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing
Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing Open
FAM60A, traditionally linked to chromatin remodeling within the Sin3/HDAC complex, has emerged as a critical regulator in RNA splicing. Employing an integrative approach that combines immunological assays, CRISPR/Cas9 technology, comprehen…
View article: Perturbation of BRMS1 interactome reveals pathways that impact metastasis
Perturbation of BRMS1 interactome reveals pathways that impact metastasis Open
Breast Cancer Metastasis Suppressor 1 (BRMS1) expression is associated with longer patient survival in multiple cancer types. Understanding BRMS1 functionality will provide insights into both mechanism of action and will enhance potential …
View article: Perturbation of BRMS1 interactome reveals pathways that impact cell migration
Perturbation of BRMS1 interactome reveals pathways that impact cell migration Open
Breast Cancer Metastasis Suppressor 1 (BRMS1) expression is associated with longer patient survival in multiple cancer types. Understanding BRMS1 functionality will provide insights into both mechanism of action and will enhance potential …
View article: Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy
Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy Open
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is one of the pressing contemporary public health challenges. Investigations into the genomic structure of SARS-CoV-2 may inform ongoin…
View article: BRMS1: a multifunctional signaling molecule in metastasis
BRMS1: a multifunctional signaling molecule in metastasis Open