Rosângela Vieira de Andrade
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View article: Clock Gene Expression Modulation by Low- and High-Intensity Exercise Regimens in Aging Mice
Clock Gene Expression Modulation by Low- and High-Intensity Exercise Regimens in Aging Mice Open
The circadian rhythm controls the sleep/wake cycle and a wide variety of metabolic and physiological functions. Clock genes regulate it in response to both external and endogenous stimuli, and their expression may change because of aging, …
View article: Development and Evaluation of a Molecular Test for Monkeypox Virus in the Federal District, Brazil
Development and Evaluation of a Molecular Test for Monkeypox Virus in the Federal District, Brazil Open
Background: Monkeypox virus, the etiological agent of Mpox, is a double-stranded DNA virus belonging to the Orthopoxvirus genus that has attracted increasing attention due to sporadic outbreaks in humans. In 2022, it was responsible for th…
View article: SHIP identifies genomic safe harbors in eukaryotic organisms using genomic general feature annotation
SHIP identifies genomic safe harbors in eukaryotic organisms using genomic general feature annotation Open
View article: EVALUATING TREATMENT TIMELINES AND SURVIVAL OUTCOMES FOR PRIMARY CNS LYMPHOMA: A CROSS-SECTIONAL EVALUATION
EVALUATING TREATMENT TIMELINES AND SURVIVAL OUTCOMES FOR PRIMARY CNS LYMPHOMA: A CROSS-SECTIONAL EVALUATION Open
Objectives: This study assesses clinical outcomes for primary central nervous system lymphoma (PCNSL) patients, particularly focusing on the timelines from diagnosis to hospital arrival, treatment initiation, and overall survival. It exami…
View article: Epithelial regenerative activity of topic administration of canine adipose-derived mesenchymal stem cells secretome in eye drops format—an in vitro study
Epithelial regenerative activity of topic administration of canine adipose-derived mesenchymal stem cells secretome in eye drops format—an in vitro study Open
View article: Screening of the Skin-Regenerative Potential of Antimicrobial Peptides: Clavanin A, Clavanin-MO, and Mastoparan-MO
Screening of the Skin-Regenerative Potential of Antimicrobial Peptides: Clavanin A, Clavanin-MO, and Mastoparan-MO Open
Skin wound healing is coordinated by a delicate balance between proinflammatory and anti-inflammatory responses, which can be affected by opportunistic pathogens and metabolic or vascular diseases. Several antimicrobial peptides (AMPs) pos…
View article: IL-10 and IL-1β Serum Levels, Genetic Variants, and Metabolic Syndrome: Insights into Older Adults’ Clinical Characteristics
IL-10 and IL-1β Serum Levels, Genetic Variants, and Metabolic Syndrome: Insights into Older Adults’ Clinical Characteristics Open
Populational aging is marked by chronic noncommunicable diseases, such as metabolic syndrome (MetS). IL-10 and IL-1β are pleiotropic cytokines with multiple biological effects linked to metabolic disorders. This cross-sectional study asses…
View article: IL-10 and IL-1β Serum Levels, Genetic Variants, and Metabolic Syndrome: Insights into Older Adults' Clinical Characteristics
IL-10 and IL-1β Serum Levels, Genetic Variants, and Metabolic Syndrome: Insights into Older Adults' Clinical Characteristics Open
Populational aging is marked by chronic non-communicable diseases, such as metabolic syndrome (MetS). IL-10 and IL-1β are pleiotropic cytokines with multiple biological effects linked to metabolic disorders. This cross-sectional study…
View article: Evaluation of the efficacy of the in vitro micronucleus method using a commercial kit and comparison with the microscopy method
Evaluation of the efficacy of the in vitro micronucleus method using a commercial kit and comparison with the microscopy method Open
In vitro micronucleus testing is an important tool in the investigation of the genotoxic potential of products. Performing the test by the optical microscopy method requires training and attention from the technician reading the slides and…
View article: Association between host defense peptide IDR-1002 and ciprofloxacin: effects on human dental pulp cells
Association between host defense peptide IDR-1002 and ciprofloxacin: effects on human dental pulp cells Open
Aim: to evaluate the effects of the association of host defense peptide IDR-1002 and ciprofloxacin on human dental pulp cells (hDPSCs). Materials and methods: hDPSCs were stimulated in culture with ciprofloxacin and IDR-1002. Cell viabilit…
View article: Evaluation of the effects of the recommended oral dose of diflubenzuron on bovine sperm and oocyte quality using CASA and OPU-IVEP
Evaluation of the effects of the recommended oral dose of diflubenzuron on bovine sperm and oocyte quality using CASA and OPU-IVEP Open
Introduction The aim of this study was to evaluate potential effects of diflubenzuron on the production and quality of gametes, and on in vitro embryo production (IVEP) outcomes, in cattle. Methods Two experiments were performed, the first…
View article: Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study
Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study Open
View article: Expanding the Toolbox for Functional Genomics in Fonsecaea pedrosoi: The Use of Split-Marker and Biolistic Transformation for Inactivation of Tryptophan Synthase (trpB) Gene
Expanding the Toolbox for Functional Genomics in Fonsecaea pedrosoi: The Use of Split-Marker and Biolistic Transformation for Inactivation of Tryptophan Synthase (trpB) Gene Open
Chromoblastomycosis (CBM) is a disease caused by several dematiaceous fungi from different genera, and Fonsecaea is the most common which has been clinically isolated. Genetic transformation methods have recently been described; however, m…
View article: Impacto da qualidade seminal e dos fatores relativos ao macho na produção in vitro de embriões bovinos
Impacto da qualidade seminal e dos fatores relativos ao macho na produção in vitro de embriões bovinos Open
View article: Induced resistance to ifosfamide in osteosarcoma cells suggests a more aggressive tumor profile
Induced resistance to ifosfamide in osteosarcoma cells suggests a more aggressive tumor profile Open
View article: <i>In vitro</i> antitumor activity in breast cancer cells (SKBR3 and PMC42) of <i>Ruta graveolens</i> in homeopathic dilution
<i>In vitro</i> antitumor activity in breast cancer cells (SKBR3 and PMC42) of <i>Ruta graveolens</i> in homeopathic dilution Open
Objectives: Given the need to establish less invasive treatments that improve the patient’s quality of life and still have antitumour effects, this study aimed to evaluate the behaviour of breast cancer tumour cells (SKBR3 and PMC42) by tr…
View article: In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album
In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album Open
Introduction The use of mesenchymal stem cells (MSC) in cytotoxicity tests is an in-vitro alternative model for predicting initial doses. Homeopathic medicines may stimulate the immune system to combat a pathology effectively and have been…
View article: Homeopathic Viscum Album at Potencies D3 and 200CH Presents Cytokine Modulatory Effect Produced by in vitro Culture of Mesenchymal Stem Cells
Homeopathic Viscum Album at Potencies D3 and 200CH Presents Cytokine Modulatory Effect Produced by in vitro Culture of Mesenchymal Stem Cells Open
Viscum Album (VA) has been widely used as adjuvant therapy in cancer. Its anticancer activity has been attributed to a combination of cytotoxic, immunomodulatory, and anti-inflammatory properties.
View article: Induced Resistance to Ifosfamide in Osteosarcoma Cells Suggests a More Aggressive Tumor Profile
Induced Resistance to Ifosfamide in Osteosarcoma Cells Suggests a More Aggressive Tumor Profile Open
View article: Differentially Expressed Genes in Resistance-Induced Osteosarcoma U2Os Lineage
Differentially Expressed Genes in Resistance-Induced Osteosarcoma U2Os Lineage Open
View article: Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease? Open
We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal dis…
View article: Safety Assessment of Intravenous Application of the Homeopathic Medicine Viscum Album D3 in Dogs
Safety Assessment of Intravenous Application of the Homeopathic Medicine Viscum Album D3 in Dogs Open
Background: Viscum album (VA) extracts have a wide variety of biologically active compounds that can be used in the treatment of various diseases, with cancer being the main one. However, few data on the effects of homeopathic VA are found…
View article: Telomere Length, SIRT1, and Insulin in Male Master Athletes: The Path to Healthy Longevity?
Telomere Length, SIRT1, and Insulin in Male Master Athletes: The Path to Healthy Longevity? Open
Lower SIRT1 and insulin resistance are associated with accelerated telomere shortening. This study investigated whether the lifestyle of master athletes can attenuate these age-related changes and thereby slow aging. We compared insulin, S…
View article: Viscum Album - Literature Review
Viscum Album - Literature Review Open
View article: Homoeopathic Viscum album (10-3) is More Cytotoxic to in vitro Culture of Human Breast Cancer Cell Line than to Human Mesenchymal Stem Cells
Homoeopathic Viscum album (10-3) is More Cytotoxic to in vitro Culture of Human Breast Cancer Cell Line than to Human Mesenchymal Stem Cells Open
BACKGROUND Adenocarcinomas can be of several types, and MCF-7 is an adenocarcinoma of human breast cell line useful as preclinical model to screen therapeutic agents such as ultra-diluted Viscum album, an European plant whose extract is co…
View article: Renoprotection Induced by Aerobic Training Is Dependent on Nitric Oxide Bioavailability in Obese Zucker Rats
Renoprotection Induced by Aerobic Training Is Dependent on Nitric Oxide Bioavailability in Obese Zucker Rats Open
Aerobic training (AT) promotes several health benefits that may attenuate the progression of obesity associated diabetes. Since AT is an important nitric oxide (NO - ) inducer mediating kidney‐healthy phenotype, the present study is aimed …
View article: Regulated promoters applied to plant engineering: an insight over promising soybean promoters under biotic stress and their cis-elements
Regulated promoters applied to plant engineering: an insight over promising soybean promoters under biotic stress and their cis-elements Open
Promoters are upstream gene regulatory sequences recognized by transcription factors (TFs) involved in controlling transcription initiation and progression. For modern crop improvement, the design of efficient gene constructs relies on pro…
View article: Homoeopathic <i>Viscum album</i> extract inhibits the growth of osteosarcoma cells
Homoeopathic <i>Viscum album</i> extract inhibits the growth of osteosarcoma cells Open
Objectives: This study is aimed to evaluate the cytotoxic action of two homoeopathic medicines that are derived from Viscum album (VA) extract. Materials and Methods: An osteosarcoma cell line was cultured in the presence of two homoeopath…
View article: Clock Genes, Inflammation and the Immune System—Implications for Diabetes, Obesity and Neurodegenerative Diseases
Clock Genes, Inflammation and the Immune System—Implications for Diabetes, Obesity and Neurodegenerative Diseases Open
Inflammation is a common feature of several diseases, including obesity, diabetes and neurodegenerative disorders. Circadian clock genes are expressed and oscillate in many cell types such as macrophages, neurons and pancreatic β cells. Du…
View article: Reduction of Management Costs and Avoidance of Air Release of Carcinogens Through a Waste Segregation Program in a Brazilian Medical Institution
Reduction of Management Costs and Avoidance of Air Release of Carcinogens Through a Waste Segregation Program in a Brazilian Medical Institution Open
Hospital waste management is a current sustainability challenge. Although not always performed, the most applied approach in current protocols is the proper segregation of waste. The incineration of hospital waste is an significant source …