Raffaella Mormile
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View article: Artificial intelligence and radiological imaging in oncology: state of the art and future perspectives
Artificial intelligence and radiological imaging in oncology: state of the art and future perspectives Open
Artificial intelligence (AI), in integration with the domain of radiogenomics, is transforming the perspective of oncology by bringing in imaging data with genomic profiles, to improve cancer diagnosis and treatment planning, and personali…
View article: BASELINE THROMBIN GENERATION TEST DOES NOT PREDICT THROMBOTIC EVENTS IN ACUTE LEUKEMIA: A MONOCENTRIC PROSPECTIVE STUDY
BASELINE THROMBIN GENERATION TEST DOES NOT PREDICT THROMBOTIC EVENTS IN ACUTE LEUKEMIA: A MONOCENTRIC PROSPECTIVE STUDY Open
Thromboembolic and hemorrhagic complications are significant causes of morbidity and mortality in patients with acute leukemias (AL). While AL is characterized by a complex hemostatic imbalance, conventional coagulation tests and platelet …
View article: Analysis of radiation dose reduction in oncological followup cases by using dual energy CT
Analysis of radiation dose reduction in oncological followup cases by using dual energy CT Open
Background Concern about radiation effects is particularly significant for cancer patients who require frequent imaging for follow-up assessments. Computed tomography (CT) is a key tool in the diagnosis and monitoring of cancer. Purpose To…
View article: Optimization and image quality in CT studies: application of DRLs based on clinical indication
Optimization and image quality in CT studies: application of DRLs based on clinical indication Open
The use of ionizing radiation in computed tomography (CT) has significantly enhanced diagnostic accuracy and clinical decision-making. However, optimizing CT protocols is crucial to balance the diagnostic benefits with potential radiation …
View article: Phenotypic Manifestations of a New Variant in <i>HDAC4</i> Gene
Phenotypic Manifestations of a New Variant in <i>HDAC4</i> Gene Open
Psychomotor development delays affect 1%–3% of children and encompass a wide range of motor, cognitive, and social impairments. The histone deacetylase 4 ( HDAC4 ) gene, critical for neurodevelopmental pathways, has been associated with de…
View article: Malignant Pleural Mesothelioma CT Imaging: How to Measure It Correctly?
Malignant Pleural Mesothelioma CT Imaging: How to Measure It Correctly? Open
Background: Malignant pleural mesothelioma is the most common primary tumor of the pleura. The unique growth pattern of malignant pleural mesothelioma makes it difficult to apply the Response Evaluation Criteria for Solid Tumors (RECIST). …
View article: Endometriosis and depression: only a psychological effect or even a causal occurrence?
Endometriosis and depression: only a psychological effect or even a causal occurrence? Open
View article: Covidsomnia: is the sirtuin1-NAD + axis the clue of the matter?
Covidsomnia: is the sirtuin1-NAD + axis the clue of the matter? Open
View article: Aspirin Use for Primary Prevention of HCC: Friend or Foe?
Aspirin Use for Primary Prevention of HCC: Friend or Foe? Open
View article: Il-6, Il-1β and cytokine-targeted therapy for COVID -19 patients: two more reasons to take into account statins?
Il-6, Il-1β and cytokine-targeted therapy for COVID -19 patients: two more reasons to take into account statins? Open
View article: Myocarditis and pericarditis following mRNA COVID-19 vaccination in younger patients: is there a shared thread?
Myocarditis and pericarditis following mRNA COVID-19 vaccination in younger patients: is there a shared thread? Open
Rare cases of myocarditis and pericarditis after COVID-19 mRNA vaccination have been recently reported in male adolescents and young adults. Acute myocarditis and pericarditis following COVID-19 mRNA vaccination in male adolescents and you…
View article: Obesity and Severe COVID-19 in the Young: Is Downregulation of miR-126 a Piece of the SARS-COV2 Pathogenicity Puzzle?
Obesity and Severe COVID-19 in the Young: Is Downregulation of miR-126 a Piece of the SARS-COV2 Pathogenicity Puzzle? Open
View article: COVID-19 myocarditis and lasting heart damage: is deregulation of the Beclin1-Survivin axis the critical step of pathogenesis?
COVID-19 myocarditis and lasting heart damage: is deregulation of the Beclin1-Survivin axis the critical step of pathogenesis? Open
The COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infection poses a serious threat for the heart [1,2]. Myocardial damage has been observed in a larg...
View article: Letter to the editor: What about cholesterol as a novel biomarker for bladder and kidney cancer diagnosis and surveillance? In memory of my dad Sossio Mormile
Letter to the editor: What about cholesterol as a novel biomarker for bladder and kidney cancer diagnosis and surveillance? In memory of my dad Sossio Mormile Open
View article: IL-6 and Breast Cancer Risk: No More Than the Tip of an Iceberg?
IL-6 and Breast Cancer Risk: No More Than the Tip of an Iceberg? Open
View article: Nut Consumption and Lung Cancer Risk: Is Linoleic Acid the Secret Weapon?
Nut Consumption and Lung Cancer Risk: Is Linoleic Acid the Secret Weapon? Open
View article: Hyperthermia, positive feedback loop with IL-6 and risk of NSCLC progression: a tangle to unravel?
Hyperthermia, positive feedback loop with IL-6 and risk of NSCLC progression: a tangle to unravel? Open
View article: Total Serum Cholesterol and Pancreatic Cancer Risk: What Is the Link?
Total Serum Cholesterol and Pancreatic Cancer Risk: What Is the Link? Open
View article: Immune Checkpoint Inhibitors in HIV-Positive Patients With NSCLC: Is it Time for Outlining a Protocol?
Immune Checkpoint Inhibitors in HIV-Positive Patients With NSCLC: Is it Time for Outlining a Protocol? Open
View article: Type 2 diabetes and susceptibility to atrial fibrillation: the two facets of downregulation of MiR-126?
Type 2 diabetes and susceptibility to atrial fibrillation: the two facets of downregulation of MiR-126? Open
Type 2 diabetes (T2D) has long been recognized to be a risk factor for atrial fibrillation (AF) 1. However, it is still unknown whether T2D directly affects the atrial tissues or whether different pathways are implicated in the pathogenesi…
View article: Metformin and Lung Cancer: The Final Blow to the Obesity Paradox?
Metformin and Lung Cancer: The Final Blow to the Obesity Paradox? Open
View article: Gestational Diabetes Mellitus and Incident Invasive Breast Cancer—Letter
Gestational Diabetes Mellitus and Incident Invasive Breast Cancer—Letter Open
In a recent publication, Powe and colleagues (1) focused on the association between the history of gestational diabetes mellitus (GDM) and risk of incident invasive breast cancer (1). They conducted a prospective analysis among parous wome…
View article: The Obesity Paradox and Cancer—Letter
The Obesity Paradox and Cancer—Letter Open
In a recent publication, Strulov Shachar and colleagues (1) focused on the obesity paradox in cancer (1). The authors discuss hypothetical explanations and take a step beyond body mass index (BMI) or simple weights alone to present other u…
View article: Aspirin and Pancreatic Cancer—Letter
Aspirin and Pancreatic Cancer—Letter Open
In a recent publication by Risch and colleagues (1), regular use of aspirin was associated with reduced risk of pancreatic cancer (1). Few options besides the avoidance of smoking and obesity are available to prevent pancreatic cancer (1).…
View article: Severe influenza symptoms in celiac disease: implications of CD103− dendritic cells?
Severe influenza symptoms in celiac disease: implications of CD103− dendritic cells? Open
View article: Vitamin D Intake and its Protective Role in Multiple Sclerosis: The Checkmate to Survivin?
Vitamin D Intake and its Protective Role in Multiple Sclerosis: The Checkmate to Survivin? Open
Vitamin D has long been speculated to reduce the risk of multiple sclerosis (MS). However, its role in development and modulating the course of MS has yet to be clarified. To date, there is no scientific evidence for the use of vitamin D a…
View article: Antenatal Dexamethasone For Women at Risk af Preterm Birth and Intraventricular Haemorrhage: What is the Truth?
Antenatal Dexamethasone For Women at Risk af Preterm Birth and Intraventricular Haemorrhage: What is the Truth? Open
Administration of antenatal corticosteroids to pregnant women with imminent delivery of a newborn at 24 to 34 weeks of gestation represents one of the most important advances in perinatal medicine in the past 25 years (1, 2). A single cour…
View article: Induction of GLUT4 by inhibiting IFN-γ: a winning move to halt type 2 diabetes?
Induction of GLUT4 by inhibiting IFN-γ: a winning move to halt type 2 diabetes? Open
View article: Schizophrenia in celiac disease: a myth or reality?
Schizophrenia in celiac disease: a myth or reality? Open
View article: Non-Hodgkin lymphoma in celiac disease: causality or casuality on the scene?
Non-Hodgkin lymphoma in celiac disease: causality or casuality on the scene? Open