Rosemarie van Dort
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View article: Hyperintense lesions suspect for acute cerebral microbleeds on ultra-high field T1 weighted 7 Tesla MRI in patients with cerebral amyloid angiopathy
Hyperintense lesions suspect for acute cerebral microbleeds on ultra-high field T1 weighted 7 Tesla MRI in patients with cerebral amyloid angiopathy Open
7 T T1 hyperintense lesions were identified in approximately one in ten patients in our cohort. Acute CMBs were more often identified on 7 T MRI in comparison to 3 T MRI. This highlights the additional value of ultra-high field MRI in the …
View article: One-Year Radiologic Progression in Sporadic and Hereditary Cerebral Amyloid Angiopathy
One-Year Radiologic Progression in Sporadic and Hereditary Cerebral Amyloid Angiopathy Open
CAA is a radiologically progressive disease even in the short-term. After 1 year, all symptomatic and most of the presymptomatic participants showed progression of at least 1 MRI-marker. CMBs and WMH volume (in symptomatic CAA) and WMH vol…
View article: Cognition in (pre)symptomatic Dutch‐type hereditary and sporadic cerebral amyloid angiopathy
Cognition in (pre)symptomatic Dutch‐type hereditary and sporadic cerebral amyloid angiopathy Open
INTRODUCTION Cerebral amyloid angiopathy (CAA) is a main cause of cognitive dysfunction in the elderly. We investigated specific cognitive profiles, cognitive function in the stage before intracerebral hemorrhage (ICH), and the association…
View article: Quality of life, depression and anxiety in cerebral amyloid angiopathy: A cross‐sectional study
Quality of life, depression and anxiety in cerebral amyloid angiopathy: A cross‐sectional study Open
Background and Purpose Data on health‐related quality of life (HRQoL) and mood in cerebral amyloid angiopathy (CAA), a disease characterized by stroke and cognitive decline, are limited. We aimed to investigate the impacted domains of life…
View article: Microstructural white matter damage on MRI is associated with disease severity in Dutch-type cerebral amyloid angiopathy
Microstructural white matter damage on MRI is associated with disease severity in Dutch-type cerebral amyloid angiopathy Open
Peak width of skeletonized mean diffusivity (PSMD) is an emerging diffusion-MRI based marker to study subtle early alterations to white matter microstructure. We assessed PSMD over the clinical continuum in Dutch-type hereditary CAA (D-CAA…
View article: Neuropsychiatric symptoms with focus on apathy and irritability in sporadic and hereditary cerebral amyloid angiopathy
Neuropsychiatric symptoms with focus on apathy and irritability in sporadic and hereditary cerebral amyloid angiopathy Open
Background Neuropsychiatric symptoms (NPS) may affect cognition, but their burden in cerebral amyloid angiopathy (CAA), one of the main causes of intracerebral hemorrhage (ICH) and dementia in the elderly, remains unclear. We investigated …
View article: Sensitivity of the Boston criteria version 2.0 in Dutch-type hereditary cerebral amyloid angiopathy
Sensitivity of the Boston criteria version 2.0 in Dutch-type hereditary cerebral amyloid angiopathy Open
Background and aim: The revised Boston criteria v2.0 for cerebral amyloid angiopathy (CAA) add two radiological markers to the existing criteria: severe visible perivascular spaces in the centrum semiovale and white matter hyperintensities…