Ross Sadler
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View article: Exploring the relationship between housing conditions and Métis Nation of Ontario citizen’s health: a qualitative study
Exploring the relationship between housing conditions and Métis Nation of Ontario citizen’s health: a qualitative study Open
View article: Persistent Organic Pollutant Pesticides in the Soil Environment
Persistent Organic Pollutant Pesticides in the Soil Environment Open
View article: The incidence of anti-HMGCR immune-mediated necrotizing myopathy: an Australian and UK retrospective multi-site cohort study
The incidence of anti-HMGCR immune-mediated necrotizing myopathy: an Australian and UK retrospective multi-site cohort study Open
Objectives Immune-mediated necrotizing myopathy (IMNM) with autoantibodies targeting 3-hydroxy-3-methylglutaryl-CoA reductase (anti-HMGCR) is considered a rare complication of statin therapy. We calculate the incidence of anti-HMGCR IMNM a…
View article: An international disease monitoring tool to estimate the likelihood of entry of animal health hazards from legal trade of live animals and products of animal origin imported from different countries (IDM+)
An international disease monitoring tool to estimate the likelihood of entry of animal health hazards from legal trade of live animals and products of animal origin imported from different countries (IDM+) Open
View article: Longitudinal dynamics and clinically available predictors of poor response to COVID-19 vaccination in multiple myeloma
Longitudinal dynamics and clinically available predictors of poor response to COVID-19 vaccination in multiple myeloma Open
Not available.
View article: Laboratory practice is central to earlier myeloma diagnosis: Utilizing a primary care diagnostic tool and laboratory guidelines integrated into haematology services
Laboratory practice is central to earlier myeloma diagnosis: Utilizing a primary care diagnostic tool and laboratory guidelines integrated into haematology services Open
Summary Treatment advances have greatly improved survival, but myeloma is among the worst of all cancers for delayed diagnosis, causing serious morbidities and early deaths. This delay is largely because the symptom profile of myeloma has …
View article: Determinants of durable humoral and T cell immunity in myeloma patients following <scp>COVID</scp>‐19 vaccination
Determinants of durable humoral and T cell immunity in myeloma patients following <span>COVID</span>‐19 vaccination Open
Objective To describe determinants of persisting humoral and cellular immune response to the second COVID‐19 vaccination among patients with myeloma. Methods This is a prospective, observational study utilising the RUDYstudy.org platform. …
View article: Long-term outcomes by bone marrow B-cell depletion from the R2W trial of bortezomib with cyclophosphamide and rituximab in Waldenstrőm macroglobulinaemia
Long-term outcomes by bone marrow B-cell depletion from the R2W trial of bortezomib with cyclophosphamide and rituximab in Waldenstrőm macroglobulinaemia Open
There remains a lack of consensus as to the most appropriate primary therapy in Waldenstrőm macroglobulinemia (WM). We evaluated a novel bortezomib-based combination and developed a sensitive WM-specific flow cytometry assay (limit of dete…
View article: Environmental and Human Health Hazards from Chlorpyrifos, Pymetrozine and Avermectin Application in China under a Climate Change Scenario: A Comprehensive Review
Environmental and Human Health Hazards from Chlorpyrifos, Pymetrozine and Avermectin Application in China under a Climate Change Scenario: A Comprehensive Review Open
Chlorpyrifos has been used extensively for decades to control crop pests and disease-transmitting insects; its contribution to increasing food security and minimizing the spread of diseases has been well documented. Pymetrozine and Avermec…
View article: Leaching characteristics and potential risk of heavy metals from drip irrigation pipes and mulch substrate in agricultural ecosystems
Leaching characteristics and potential risk of heavy metals from drip irrigation pipes and mulch substrate in agricultural ecosystems Open
View article: 11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial
11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial Open
View article: Exposure Routes and Health Risks Associated with Pesticide Application
Exposure Routes and Health Risks Associated with Pesticide Application Open
Pesticides play an important role in agricultural development. However, pesticide application can result in both acute and chronic human toxicities, and the adverse effects of pesticides on the environment and human health remain a serious…
View article: Environmental monitoring and potential health risk assessment from Pymetrozine exposure among communities in typical rice-growing areas of China
Environmental monitoring and potential health risk assessment from Pymetrozine exposure among communities in typical rice-growing areas of China Open
View article: Bedside and laboratory diagnostic testing in myasthenia
Bedside and laboratory diagnostic testing in myasthenia Open
View article: Natural dynamics and residues of pymetrozine for typical rice-growing areas of China
Natural dynamics and residues of pymetrozine for typical rice-growing areas of China Open
Pymetrozine has replaced toxic organophosphate pesticides previously used for controlling pests of rice crops in China. Existing data on its environmental behavior are usually related to studies on artificial plots that do not adequately a…
View article: Immune response to <scp>COVID</scp> ‐19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T‐cell response
Immune response to <span>COVID</span> ‐19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T‐cell response Open
Summary Myeloma patients frequently respond poorly to bacterial and viral vaccination. A few studies have reported poor humoral immune responses in myeloma patients to COVID‐19 vaccination. Using a prospective study of myeloma patients in …
View article: Immune response to COVID-19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T cell response
Immune response to COVID-19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T cell response Open
Summary Background Myeloma patients frequently respond poorly to bacterial and viral vaccination. A few studies have reported poor humoral immune responses in myeloma patients to COVID-19 vaccination. Methods Using a prospective study of m…
View article: COVID symptoms, testing, shielding impact on patient‐reported outcomes and early vaccine responses in individuals with multiple myeloma
COVID symptoms, testing, shielding impact on patient‐reported outcomes and early vaccine responses in individuals with multiple myeloma Open
Patients with myeloma have been shielded and self-isolated since the start of the COVID-19 pandemic, due to the concern for and subsequent reports of higher risk of severe COVID-19 disease and mortality.1 In addition, guidelines have encou…
View article: Environmental Monitoring and Potential Health Risk Assessment from Pymetrozine Exposure among Communities in Typical Rice–Growing Areas of China
Environmental Monitoring and Potential Health Risk Assessment from Pymetrozine Exposure among Communities in Typical Rice–Growing Areas of China Open
Pymetrozine is one of the most common insecticides used in China. This study was conducted to analyse Pymetrozine’s potential exposures through various environmental routes beyond the treatment area. The aim was to estimate the potential h…
View article: Improving the diagnostic pathway in patients presenting with acute kidney injury secondary to de novo multiple myeloma: a short report
Improving the diagnostic pathway in patients presenting with acute kidney injury secondary to de novo multiple myeloma: a short report Open
Multiple myeloma (MM) has a prolonged diagnostic pathway, with a median time to diagnosis of 163 days.1 Renal impairment is a common complication of MM and is associated with worse outcomes. Cast nephropathy resulting in acute kidney injur…
View article: COVID symptoms, testing, shielding impact on patient reported outcomes and early vaccine responses in individuals with multiple myeloma
COVID symptoms, testing, shielding impact on patient reported outcomes and early vaccine responses in individuals with multiple myeloma Open
Objective Multiple myeloma (MM)-related morbidity has a profound effect on quality of life (QoL), and immune function, but few studies have prospectively examined the impact of COVID-19 pandemic and attendant vaccination on both immunity a…
View article: Health Risk Assessment for Exposure to Nitrate in Drinking Water in Central Java, Indonesia
Health Risk Assessment for Exposure to Nitrate in Drinking Water in Central Java, Indonesia Open
Since 2005, over 30 epidemiological studies have evaluated the association between nitrate in drinking water and adverse health outcomes. Conditions that lead to nitrate pollution in water, such as open defecation, the proximity of septic …
View article: Agriculture Development, Pesticide Application and Its Impact on the Environment
Agriculture Development, Pesticide Application and Its Impact on the Environment Open
Pesticides are indispensable in agricultural production. They have been used by farmers to control weeds and insects, and their remarkable increases in agricultural products have been reported. The increase in the world’s population in the…
View article: Epidemiology of soil-transmitted helminth infections in Semarang, Central Java, Indonesia
Epidemiology of soil-transmitted helminth infections in Semarang, Central Java, Indonesia Open
Soil-transmitted helminth (STH) infections are endemic in Indonesia. However, prevalence data for many parts of the country are incomplete. The aim of this study was to determine human STH prevalence and knowledge and practices relating to…
View article: Maintenance therapy with infliximab or vedolizumab in inflammatory bowel disease is not associated with increased SARS-CoV-2 seroprevalence: UK experience in the 2020 pandemic
Maintenance therapy with infliximab or vedolizumab in inflammatory bowel disease is not associated with increased SARS-CoV-2 seroprevalence: UK experience in the 2020 pandemic Open
Background There has been great concern amongst clinicians and patients that immunomodulatory treatments for IBD may increase risk of SARS-CoV-2 susceptibility or progression to severe disease. Methods Sera from 640 patients attending for …
View article: A multi-disciplinary approach to igG4 related disease aids in diagnosis and management
A multi-disciplinary approach to igG4 related disease aids in diagnosis and management Open
View article: Experience from the first UK inter-regional specialist multidisciplinary meeting in the diagnosis and management of IgG4-related disease
Experience from the first UK inter-regional specialist multidisciplinary meeting in the diagnosis and management of IgG4-related disease Open
View article: In-house age-specific reference ranges for free light chains measured on the SPAPlus® analyser
In-house age-specific reference ranges for free light chains measured on the SPAPlus® analyser Open
Background The measurement of monoclonal free light chains is being increasingly utilized since the introduction of serum-based assays. It is important for laboratories to determine their own reference ranges in order to reflect the local …
View article: Impact of the “BALatrine” Intervention on Soil-Transmitted Helminth Infections in Central Java, Indonesia: A Pilot Study
Impact of the “BALatrine” Intervention on Soil-Transmitted Helminth Infections in Central Java, Indonesia: A Pilot Study Open
Many latrine campaigns in developing countries fail to be sustained because the introduced latrine is not appropriate to local socio-economic, cultural and environmental conditions, and there is an inadequate community health education com…
View article: Correction: Activated T-Follicular Helper 2 Cells Are Associated With Disease Activity in IgG4-Related Sclerosing Cholangitis and Pancreatitis
Correction: Activated T-Follicular Helper 2 Cells Are Associated With Disease Activity in IgG4-Related Sclerosing Cholangitis and Pancreatitis Open
Correction to:Clinical and Translational Gastroenterology; https://doi.org/10.14309/ctg.0000000000000020 and doi: 10.14309/ctg.0000000000000051 In the April 2019 issue of Clinical and Translational Gastroenterology, the license for the art…