Kai Rothaus
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View article: Age-Related Differences in Optical Coherence Tomography and Optical Coherence Tomography Angiography Parameters Between Healthy Children and Adults: A Comparative Analysis in a Caucasian Population
Age-Related Differences in Optical Coherence Tomography and Optical Coherence Tomography Angiography Parameters Between Healthy Children and Adults: A Comparative Analysis in a Caucasian Population Open
Purpose: Current pediatric ophthalmology practice relies on adult reference values for optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) interpretation due to limited age-appropriate normative data, po…
View article: ET-1, MMPs, ZAG, and APN Link Reduced Ocular Perfusion to Glaucoma
ET-1, MMPs, ZAG, and APN Link Reduced Ocular Perfusion to Glaucoma Open
Purpose: This study sets out to analyze the correlation of ET-1, a vasoactive peptide, along with various cytokines and vascular factors, with clinical parameters and OCT/OCT-A measurements in glaucoma participants. Methods: Eyes of partic…
View article: Morphology of Macular Neovascularization in Age-Related Macular Degeneration Influences Treatment Requirement and Visual Outcome After 1 Year
Morphology of Macular Neovascularization in Age-Related Macular Degeneration Influences Treatment Requirement and Visual Outcome After 1 Year Open
Background/Objectives: To evaluate the potential of Optical Coherence Tomography (OCT) and OCT angiography parameters in predicting treatment requirements and visual outcomes after one year in therapy-naïve eyes with neovascular age-relate…
View article: The Vascular Architecture of Macular Neovascularization in Age-Related Macular Degeneration as a Predictor of Therapy Requirements: A 3-Year Longitudinal Analysis
The Vascular Architecture of Macular Neovascularization in Age-Related Macular Degeneration as a Predictor of Therapy Requirements: A 3-Year Longitudinal Analysis Open
Background: Anti-Vascular Endothelial Growth Factor (VEGF) therapy is an effective therapy for improving and stabilizing the vision of patients with neovascular age-related macular degeneration (nAMD). However, the treatment requirements, …
View article: A Vision Transformer Architecture for the Automated Segmentation of Retinal Fluids in Spectral Domain Optical Coherence Tomography Images
A Vision Transformer Architecture for the Automated Segmentation of Retinal Fluids in Spectral Domain Optical Coherence Tomography Images Open
Neovascular age-related macular degeneration (nAMD) is one of the major causes of irreversible blindness and is characterized by accumulations of different fluids inside the retina. An early detection and activity monitoring of predominate…
View article: The Architecture of Macular Neovascularizations Predicts Treatment Responses to Anti-VEGF Therapy in Neovascular AMD
The Architecture of Macular Neovascularizations Predicts Treatment Responses to Anti-VEGF Therapy in Neovascular AMD Open
Introduction: Anti-VEGF therapy is an effective option for improving and stabilizing the vision in neovascular age-related macular degeneration (nAMD). However, the response to treatment is markedly heterogeneous. The aim of this study was…
View article: Elevated endothelin-1 levels as risk factor for an impaired ocular blood flow measured by OCT-A in glaucoma
Elevated endothelin-1 levels as risk factor for an impaired ocular blood flow measured by OCT-A in glaucoma Open
The purpose of this study was to ascertain whether a correlation exists between glaucoma-associated alteration of ocular vascular haemodynamics and endothelin-1 (ET-1) levels exist. Eyes of patients with cataract (n = 30) or glaucoma (n = …
View article: Vascular Analysis of Type 1, 2, and 3 Macular Neovascularization in Age-Related Macular Degeneration Using Swept-Source Optical Coherence Tomography Angiography Shows New Insights into Differences of Pathologic Vasculature and May Lead to a More Personalized Understanding
Vascular Analysis of Type 1, 2, and 3 Macular Neovascularization in Age-Related Macular Degeneration Using Swept-Source Optical Coherence Tomography Angiography Shows New Insights into Differences of Pathologic Vasculature and May Lead to a More Personalized Understanding Open
Background: The clinical appearance of macular neovascularization (MNV) in age-related macular degeneration (nAMD) varies widely, but so far, this has had no relevance in terms of therapeutic approaches or prognosis. Therefore, our purpose…
View article: Axial Stretching of Vessels in the Retinal Vascular Plexus With 3D OCT-Angiography
Axial Stretching of Vessels in the Retinal Vascular Plexus With 3D OCT-Angiography Open
This work gives a systematic insight to the stretched shape of vessels in 3D OCTA images and is relevant for further clinical research analyzing the 3D vascular network.
View article: Correlation of retinal alterations with vascular structure of macular neovascularisation in swept-source optical coherence tomography angiography in age-related macular degeneration
Correlation of retinal alterations with vascular structure of macular neovascularisation in swept-source optical coherence tomography angiography in age-related macular degeneration Open
Purpose The aim of this study was to find out whether the vascular architecture of untreated macular neovascularisations (MNV) in neovascular age-related macular degeneration (nAMD) as visualised with optic coherence tomography angiography…
View article: Occurrence and Risk Factors for Macular Edema in Patients with Juvenile Idiopathic Arthritis-Associated Uveitis
Occurrence and Risk Factors for Macular Edema in Patients with Juvenile Idiopathic Arthritis-Associated Uveitis Open
Purpose: To analyze occurrence and risk factors for macular edema (ME) in juvenile idiopathic arthritis-associated uveitis (JIA-U). Methods: Retrospective analysis of patients with JIA-U at a tertiary referral uveitis center between 2000 a…
View article: <p>Quantitative Comparison of the Vascular Structure of Macular Neovascularizations Between Swept-Source and Spectral-Domain Optical Coherence Tomography Angiography</p>
Quantitative Comparison of the Vascular Structure of Macular Neovascularizations Between Swept-Source and Spectral-Domain Optical Coherence Tomography Angiography Open
MNV area is closely comparable between devices using SS-OCTA and SD-OCTA imaging. However, the two methods differ significantly in their precise assessment of the vascular morphology (FD, flow density, nodes per area). Therefore, results o…
View article: Quantitative Comparison of the Vascular Structure of Macular Neovascularizations Between Swept-Source and Spectral-Domain Optical Coherence Tomography Angiography
Quantitative Comparison of the Vascular Structure of Macular Neovascularizations Between Swept-Source and Spectral-Domain Optical Coherence Tomography Angiography Open
Henrik Faatz,1 Kai Rothaus,1 Martin Ziegler,1 Marius Book,1 Claudia Lommatzsch,1,2 Georg Spital,1 Matthias Gutfleisch,1 Daniel Pauleikhoff,1,3,4 Albrecht Lommatzsch1,3,4 1Department of Ophthalmology, St. Franziskus Hospital, Münster, Germa…
View article: Morphologic analysis of macular neovascularizations by OCT angiography—Technical limitations in the comparison of 3×3mm and 6×6mm images
Morphologic analysis of macular neovascularizations by OCT angiography—Technical limitations in the comparison of 3×3mm and 6×6mm images Open
In quantitative analysis of the morphologic parameters of MNV in 3×3mm and 6×6mm images, the structures are not directly equivalent in the two sizes of scan. The images must be evaluated on an individual basis.
View article: Vessel Density in Glaucoma of Different Entities as Measured with Optical Coherence Tomography Angiography
Vessel Density in Glaucoma of Different Entities as Measured with Optical Coherence Tomography Angiography Open
C Lommatzsch,1 K Rothaus,1 JM Koch,1 C Heinz,1,2 S Grisanti3 1Department of Ophthalmology, St. Franziskus Hospital, Muenster 48145, Germany; 2Department of Ophthalmology, University of Essen, Essen, Germany; 3Department of Ophthalmology, U…
View article: Changes in the OCT angiographic appearance of type 1 and type 2 CNV in exudative AMD during anti-VEGF treatment
Changes in the OCT angiographic appearance of type 1 and type 2 CNV in exudative AMD during anti-VEGF treatment Open
Objective Optical coherence tomography angiography (OCT-A) enables detailed visualisation of the vascular structure of choroidal neovascularisation (CNV). The aim of this study was to determine whether mathematically ascertained OCT-A vasc…
View article: <p>Vessel Density in Glaucoma of Different Entities as Measured with Optical Coherence Tomography Angiography</p>
Vessel Density in Glaucoma of Different Entities as Measured with Optical Coherence Tomography Angiography Open
OCTA can detect a difference in VD in the nasal inferior peripapillary sector in NTG compared with POAG and XFG. These findings may help to improve the understanding of further pathophysiological mechanisms.
View article: Influence of Inflammation in Uveitis on Confocal Scanning Laser Tomography and Optical Coherence Tomography Measurements
Influence of Inflammation in Uveitis on Confocal Scanning Laser Tomography and Optical Coherence Tomography Measurements Open
Purpose: To evaluate the influence of active inflammation in uveitis on confocal scanning laser tomography (CSLT) and optical coherence tomography (OCT) measurements. Methods: Prospective enrollment of patients (64 eyes) with non-infectiou…
View article: Identification of Ocular Autoantigens Associated With Juvenile Idiopathic Arthritis-Associated Uveitis
Identification of Ocular Autoantigens Associated With Juvenile Idiopathic Arthritis-Associated Uveitis Open
The purpose of the current study was to analyze the binding patterns of serum autoantibodies from juvenile idiopathic arthritis (JIA) and JIA-associated uveitis (JIAU) patients to proteomes from different ocular tissues and to identify pot…
View article: Retinal perfusion 6 months after trabeculectomy as measured by optical coherence tomography angiography
Retinal perfusion 6 months after trabeculectomy as measured by optical coherence tomography angiography Open
To investigate potential changes of vessel density (VD) at the optic nerve head (ONH) and the macula 6 months after trabeculectomy (TE). In a prospective monocentric study, 19 eyes with open-angle glaucoma were treated with TE + MMC (mitom…
View article: Progression characteristics of ellipsoid zone loss in macular telangiectasia type 2
Progression characteristics of ellipsoid zone loss in macular telangiectasia type 2 Open
Purpose To investigate the progression characteristics of ellipsoid zone ( EZ ) loss in eyes with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements, and their relevance for visual acuity. Methods Participa…
View article: Vessel density in OCT angiography permits differentiation between normal and glaucomatous optic nerve heads
Vessel density in OCT angiography permits differentiation between normal and glaucomatous optic nerve heads Open
OCTA allows non-invasive quantification of the peripapillary and papillary VD, which is significantly reduced in glaucomatous eyes and accurately distinguishes between healthy and diseased eyes. OCTA expands the spectrum of procedures for …