Rowan Wuestenenk
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View article: The Phenotypical and Functional Effect of PGE2 on Human Macrophages
The Phenotypical and Functional Effect of PGE2 on Human Macrophages Open
Prostaglandin E2 (PGE2) is one important immunosuppressive factor within the tumor microenvironment (TME). Signaling through E‐prostanoid receptor type 2 (EP2) and EP4, PGE2 promotes suppressive immune cell phenotypes and impairs antitumor…