Roy Eldor
YOU?
Author Swipe
View article: <b>Gradual titration of semaglutide results in better treatment adherence and fewer adverse events: A randomized controlled open label pilot study examining a 16-week flexible titration regimen vs. label-recommended 8-week semaglutide titration regimen</b>
<b>Gradual titration of semaglutide results in better treatment adherence and fewer adverse events: A randomized controlled open label pilot study examining a 16-week flexible titration regimen vs. label-recommended 8-week semaglutide titration regimen</b> Open
Objective: To determine if a slower, flexible titration regimen of semaglutide would improve adherence and reduce gastrointestinal adverse events (GI-AEs) compared to the label-recommended regimen in type 2 diabetes patients (T2DM).Researc…
View article: Metabolic and functional factors associated with a change in resting metabolic rate among older adults with type 2 diabetes– results from the CEV-65 randomized trial
Metabolic and functional factors associated with a change in resting metabolic rate among older adults with type 2 diabetes– results from the CEV-65 randomized trial Open
CRT, VegMedD, and empagliflozin showed similar effects on RMR in elderly with T2DM. Factors predicting changes in RMR are sleep hours, fat percentage, and leg strength, with those who increased/did not change their RMR presenting greater i…
View article: The Association Between Elevated Thyroid-Stimulating Hormone Levels and Prolonged Length of Stay Among Adult Diabetic Patients Hospitalized in Internal Medicine Departments: A Large Historical Cohort Study
The Association Between Elevated Thyroid-Stimulating Hormone Levels and Prolonged Length of Stay Among Adult Diabetic Patients Hospitalized in Internal Medicine Departments: A Large Historical Cohort Study Open
Background/Objectives: Type 2 diabetes mellitus (DM2) and hypothyroidism are two of the most common endocrine disorders in clinical practice. Hospital length of stay (LOS) is a quality metric of the health systems. We evaluated the associa…
View article: Identifying Diabetes Related-Complications in a Real-World Free-Text Electronic Medical Records in Hebrew Using Natural Language Processing Techniques
Identifying Diabetes Related-Complications in a Real-World Free-Text Electronic Medical Records in Hebrew Using Natural Language Processing Techniques Open
Background: Studies have demonstrated that 50% to 80% of patients do not receive an International Classification of Diseases (ICD) code assigned to their medical encounter or condition. For these patients, their clinical information is mos…
View article: Clinical characteristics and healthcare utilisation associated with undiagnosed cognitive impairment in elderly patients with diabetes in a primary care setting: a population-based cohort study
Clinical characteristics and healthcare utilisation associated with undiagnosed cognitive impairment in elderly patients with diabetes in a primary care setting: a population-based cohort study Open
Objectives The objective of this study is to report the prevalence, clinical characteristics and healthcare utilisation of patients with type 2 diabetes (T2DM) and previously undiagnosed cognitive impairment who were identified as having a…
View article: FRI305 Impulse Control Disorders In Patients With Prolactinomas And Non-Functioning Pituitary Adenomas Treated With Dopamine Agonists
FRI305 Impulse Control Disorders In Patients With Prolactinomas And Non-Functioning Pituitary Adenomas Treated With Dopamine Agonists Open
Disclosure: T. Kolitz: None. E. Shemesh: None. A. Nathan: None. R. Eldor: None. E. Izkhakov: None. Y. Greenman: None. Objective Impulse control disorder (ICD) is a well-recognized side effect of dopamine agonist (DA) treatment in patients …
View article: Hand Grip Strength Relative to Waist Circumference as a Means to Identify Men and Women Possessing Intact Mobility in a Cohort of Older Adults with Type 2 Diabetes
Hand Grip Strength Relative to Waist Circumference as a Means to Identify Men and Women Possessing Intact Mobility in a Cohort of Older Adults with Type 2 Diabetes Open
Possessing intact mobility in older adults assures their continued independence. The early identification of reduced mobility in older adults with type 2 diabetes (T2DM) is paramount for preventing their future physical deterioration. Hand…
View article: PSUN187 Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes
PSUN187 Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes Open
Background Aging and type 2 diabetes (T2DM) are associated with an increased risk of developing sarcopenia which is associated with poor outcomes and may necessitate specific treatment. Diagnosis of sarcopenia often requires the referral o…
View article: Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes
Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes Open
Background Aging and type 2 diabetes (T2DM) are associated with an increased risk of sarcopenia. Diagnosis of sarcopenia is commonly done using dual-energy X-ray absorptiometry (DXA) in specialized settings. Another available method for as…
View article: The Effects of Metabolism Tracker Device (Lumen) Usage on Metabolic Control in Adults with Prediabetes: Pilot Clinical Trial
The Effects of Metabolism Tracker Device (Lumen) Usage on Metabolic Control in Adults with Prediabetes: Pilot Clinical Trial Open
Introduction: Prediabetes is a risk factor for type 2 diabetes mellitus (T2DM). However, it may be reversed via lifestyle changes. Lumen is a novel handheld device that measures exhaled CO2 producing results in agreement with those of indi…
View article: Flash Glucose Monitoring in Israel: Understanding Real-World Associations between Self-Monitoring Frequency and Metrics of Glycemic Control
Flash Glucose Monitoring in Israel: Understanding Real-World Associations between Self-Monitoring Frequency and Metrics of Glycemic Control Open
In Israel, people with diabetes under real-world conditions record higher rates of FreeStyle Libre scanning. These are associated with improvements in TIR, eA1c, and reduced time with glucose levels of >180 mg/dL or <54 mg/dL.
View article: Should knee extension strength testing be implemented as a screening test for identifying probable and confirmed sarcopenia in older T2DM patients?
Should knee extension strength testing be implemented as a screening test for identifying probable and confirmed sarcopenia in older T2DM patients? Open
Background The accelerated loss of muscle strength and mass observed in older type 2 diabetes mellitus (T2DM) patients due to the combined effects of diabetes and obesity, greatly increases their risk for sarcopenia. Early detection and tr…
View article: Supplementary Material for: The effects of metabolism tracker device (Lumen®) usage on metabolic control in adults with prediabetes: pilot clinical trial
Supplementary Material for: The effects of metabolism tracker device (Lumen®) usage on metabolic control in adults with prediabetes: pilot clinical trial Open
Introduction: Prediabetes is a risk factor for type 2 diabetes (T2DM). However, it may be reversed via lifestyle changes. Lumen® is a novel handheld device that measures exhaled CO2 producing results in agreement with those of indirect cal…
View article: Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes
Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes Open
Measuring resting metabolic rate (RMR) is time-consuming and expensive, and thus various equations for estimating RMR have been developed. This study’s objective was to compare five equations in elderly people with type 2 diabetes (T2DM). …
View article: Haemoglobin A1c is a predictor of COVID‐19 severity in patients with diabetes
Haemoglobin A1c is a predictor of COVID‐19 severity in patients with diabetes Open
Aim Poor outcomes of coronavirus disease 2019 (COVID‐19) have been linked to diabetes, but its relation to pre‐infection glycaemic control is still unclear. Materials and Methods To address this question, we report here the association bet…
View article: Antihyperglycemic therapy during colonoscopy preparation: A review and suggestions for practical recommendations
Antihyperglycemic therapy during colonoscopy preparation: A review and suggestions for practical recommendations Open
Patients with diabetes have distinct risks during precolonoscopy bowel preparation, caused by change of diet, change of antihyperglycemic medication regimens and diabetes‐related complications and comorbidities. These risks include hypogly…
View article: Exenatide modulates visual cortex responses
Exenatide modulates visual cortex responses Open
Background Increasing evidence suggests that metabolism affects brain physiology. Here, we examine the effect of GLP‐1 on simple visual‐evoked functional Magnetic Resonance Imaging (fMRI) responses in cortical areas. Methods Lean (n = 10) …
View article: Ertugliflozin plus sitagliptin versus either individual agent over 52 weeks in patients with type 2 diabetes mellitus inadequately controlled with metformin: The <scp>VERTIS FACTORIAL</scp> randomized trial
Ertugliflozin plus sitagliptin versus either individual agent over 52 weeks in patients with type 2 diabetes mellitus inadequately controlled with metformin: The <span>VERTIS FACTORIAL</span> randomized trial Open
Aim To evaluate the efficacy and safety of ertugliflozin and sitagliptin co‐administration vs the individual agents in patients with type 2 diabetes who are inadequately controlled with metformin. Methods In this study ( Clinicaltrials.gov…
View article: Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects
Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects Open
Physiologic plasma FFA elevation in NGT individuals has opposing effects on PGC-1α non-CpG residue methylation (CpT demethylation and increased DNMT-3B expression), which is correlated with changes in PGC-1α expression and skeletal muscle …
View article: Efficacy and safety of the addition of ertugliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sitagliptin: The <scp>VERTIS SITA2</scp> placebo‐controlled randomized study
Efficacy and safety of the addition of ertugliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sitagliptin: The <span>VERTIS SITA2</span> placebo‐controlled randomized study Open
Aims To assess ertugliflozin in patients with type 2 diabetes who are inadequately controlled by metformin and sitagliptin. Materials and Methods In this double‐blind randomized study ( Clinicaltrials.gov NCT02036515), patients (glycated h…
View article: Additive Effect of Oral Insulin and an Oral GLP-1 Agonist on Postprandial Glucose Excursions in a Porcine Model
Additive Effect of Oral Insulin and an Oral GLP-1 Agonist on Postprandial Glucose Excursions in a Porcine Model Open
Combination therapy of insulin and a GLP-1 agonist injections is an attractive therapeutic approach in patients with type 2 diabetes mellitus, offering robust glycemic control, a reduced risk of hypoglycemia and weight gain and complementa…