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View article: First-attempt success and associated factors among emergency tracheal intubations in two addis Ababa hospitals
First-attempt success and associated factors among emergency tracheal intubations in two addis Ababa hospitals Open
FPS in these Addis Ababa hospitals (Tikur Anbessa Specialized Hospital and Zewditu Memorial Hospital) was 64.3%, a level we consider suboptimal compared with commonly cited benchmarks of ≥ 80%. This is lower than pooled benchmarks reported…
View article: Unusual presentation of complicated relapsing fever with spontaneous hemoperitoneum mimicking surgical acute abdomen: a case report
Unusual presentation of complicated relapsing fever with spontaneous hemoperitoneum mimicking surgical acute abdomen: a case report Open
Background: Louse-borne relapsing fever (LBRF) is a prevalent disease in Ethiopia, affecting malnourished and impoverished populations. Historically fatal, mortality has decreased to less than 5% with antibiotics. Symptoms include high fev…
View article: Artificial intelligence in clinical toxicology in Africa: Emerging applications and barriers
Artificial intelligence in clinical toxicology in Africa: Emerging applications and barriers Open
Artificial intelligence (AI) has a supplementary role in clinical toxicology in Africa, addressing key challenges such as delayed diagnoses, limited expertise, and inadequate healthcare infrastructure. This method has the potential to incr…
View article: Atrial fibrillation with Slow Ventricular response as a sign of Digoxin toxicity Secondary to Acute Renal failure.
Atrial fibrillation with Slow Ventricular response as a sign of Digoxin toxicity Secondary to Acute Renal failure. Open
Digoxin is a cardiac glycoside that has been used for centuries for atrial fibrillation (AFib) and congestive heart failure (CHF). Digoxin has a narrow therapeutic index with a potential for toxicity that can be life-threatening1-5. Toxici…
View article: Extended tests for evaluating post-traumatic brain injury deficits in resource-limited settings: methods and pilot study data
Extended tests for evaluating post-traumatic brain injury deficits in resource-limited settings: methods and pilot study data Open
Introduction Traumatic brain injury (TBI) is one of the leading causes of all injury-related deaths and disabilities in the world, especially in low to middle-income countries (LMICs) which also suffer from lower levels of funding for all …
View article: Point-of-Care Ultrasound to Assess Diaphragmatic Paralysis in Resource-Limited Setting: A Case Series
Point-of-Care Ultrasound to Assess Diaphragmatic Paralysis in Resource-Limited Setting: A Case Series Open
Diaphragmatic dysfunction can arise from various factors, and Guillain-Barre syndrome, characterized by acute inflammatory polyradiculoneuropathy, is one such cause that may result in respiratory failure due to diaphragmatic paralysis. Pro…
View article: A hybrid 3D-printed model for lower extremity compartment syndrome simulation
A hybrid 3D-printed model for lower extremity compartment syndrome simulation Open
Background: Compartment syndrome is a medical emergency. It should be diagnosed promptly, and therapeutic measures should be taken to avoid limb ischemia. Measurement of compartment pressure is extremely important. Model: Knowledge about c…
View article: A hybrid 3D printed model for lateral canthotomy simulation
A hybrid 3D printed model for lateral canthotomy simulation Open
Background: Ocular injuries are common complaints in the emergency department (ED). In certain instances, a hematoma builds up behind the eyeball and can lead to increased intraocular pressure (IOP), restricting circulation and threatening…
View article: Role of point of care ultrasound in the absence of radial pulse and unrecordable blood pressure during the assessment of shock: Case report
Role of point of care ultrasound in the absence of radial pulse and unrecordable blood pressure during the assessment of shock: Case report Open
Point-of-Care ultrasound is a valuable diagnostic tool that can help narrow down differential diagnostics and guide early proper management and intervention.
View article: Optic nerve sheath diameter measurement using point-of-care ultrasound to assess intracranial pressure of adult patients with traumatic brain injury in resource-limited setting
Optic nerve sheath diameter measurement using point-of-care ultrasound to assess intracranial pressure of adult patients with traumatic brain injury in resource-limited setting Open
Background: Traumatic brain injury is a disease with high mortality with increased intracranial pressure included in the emergency department. Neuroimaging and intracranial pressure monitoring are limited in resource-limited settings. Opti…
View article: Neuroendocrine-induced hyponatremia in patients with traumatic brain injury: a systematic review and meta-analysis of the epidemiology, factors and prognosis
Neuroendocrine-induced hyponatremia in patients with traumatic brain injury: a systematic review and meta-analysis of the epidemiology, factors and prognosis Open
Traumatic brain injury (TBI) is a common brain dysfunction due to an external force as opposed to disease-induced brain damage. TBI is a leading global cause of high morbidity and mortality rates in the neurosurgical department. It contrib…
View article: Role of Point of Care Ultrasound in the Absence of Radial pulse and unrecordable Blood pressure during the Assessment of Shock: Case report
Role of Point of Care Ultrasound in the Absence of Radial pulse and unrecordable Blood pressure during the Assessment of Shock: Case report Open
Point-of-care ultrasound (POCUS) has been an integral part of patient evaluation in the Emergency Department. It has been used increasingly for the evaluation of critically ill and trauma patients. We report a case of 60-year-old male pati…
View article: Molecular Neuropathology and Cerebrospinal Fluid Diagnostic Biomarkers of SARS-Cov2 Infection in Central Nervous System– A Scoping Review Protocol
Molecular Neuropathology and Cerebrospinal Fluid Diagnostic Biomarkers of SARS-Cov2 Infection in Central Nervous System– A Scoping Review Protocol Open
Introduction Despite the broad spectrum of neurological symptomatic manifestation in COVID19 patients, the brain tissue susceptibility and permissiveness to SARS-Cov2 infection is yet uncertain. This critical appraisal aims at bridging the…
View article: Isolated T wave Inversion in Lead aVL as an early sign of Inferior Wall Myocardial Infarction
Isolated T wave Inversion in Lead aVL as an early sign of Inferior Wall Myocardial Infarction Open
Electrocardiogram (ECG) is instrumental in identifying acute myocardial infarction (AMI). ST-segment elevation in a region of specific coronary vessels in an acute coronary syndrome (ACS) setting is the hallmark of AMI. Reciprocal ST depre…
View article: Distal Tracheal Obstructive Mass Leading to Bilateral Pneumothorax and Respiratory Failure
Distal Tracheal Obstructive Mass Leading to Bilateral Pneumothorax and Respiratory Failure Open
Tracheal masses are rare in occurrence, but could lead to complications depending on the speed of growth, duration and degree of obstruction. Some of the complications are recurrent pneumonia and air trapping resulting in increased intrath…
View article: Stakeholder Engagement In a Comparative Effectiveness/Implementation Study to Prevent Staphylococcus Aureus Infection Recurrence: CA-MRSA Project (CAMP2)
Stakeholder Engagement In a Comparative Effectiveness/Implementation Study to Prevent Staphylococcus Aureus Infection Recurrence: CA-MRSA Project (CAMP2) Open
CPSAC was highly effective throughout design and execution by troubleshooting recruitment and home visit challenges.
View article: Synthetic Cannabinoid Receptor Agonists Abuse in Older Adults
Synthetic Cannabinoid Receptor Agonists Abuse in Older Adults Open
Abuse of substances including alcohol, heroin, and cocaine is common in older patients and is well reported. However, use of Synthetic Cannabinoid Receptor Agonist (SCRA) in this population is very rare and has not been well documented.
View article: STAKEHOLDER ENGAGEMENT IN A COMPARATIVE EFFECTIVENESS/IMPLEMENTATION STUDY TO PREVENT CA-MRSA INFECTION RECURRENCE: CA-MRSA Project (CAMP2)
STAKEHOLDER ENGAGEMENT IN A COMPARATIVE EFFECTIVENESS/IMPLEMENTATION STUDY TO PREVENT CA-MRSA INFECTION RECURRENCE: CA-MRSA Project (CAMP2) Open
Background Methicillin-Resistant (MRSA) or Methicillin-Sensitive (MSSA) Staphylococcus aureus skin and soft tissue infections (SSTIs) pose serious clinical and public health challenges. Few protocols exist for outpatient education, decolon…
View article: Synthetic Cannabinoid Receptor Agonist-related Intoxication: Impact and Legislative Success
Synthetic Cannabinoid Receptor Agonist-related Intoxication: Impact and Legislative Success Open
Synthetic cannabinoids Receptor Agonist (SCRA) intoxication presents with various medical and psychiatric symptoms. The products are sold as K2 or Spice. The symptoms range from agitation, altered mental status (AMS), lethargy, paranoid be…
View article: Gigantic Stomach: A Rare Manifestation of Duchenne Muscular Dystrophy
Gigantic Stomach: A Rare Manifestation of Duchenne Muscular Dystrophy Open
Duchenne muscular dystrophy (DMD) is characterized by degeneration and atrophy of skeletal, cardiac, and smooth muscles after a latent period of apparently normal development and function. The gastrointestinal manifestations start in the s…
View article: Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies Open
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders of the aging population characterized by the accumulation of α-synuclein (α-syn). The mechanisms triggering α-syn toxicity are not completely unde…
View article: Development and Utilization of 3D Printed Material for Thoracotomy Simulation
Development and Utilization of 3D Printed Material for Thoracotomy Simulation Open
Medical simulation is a widely used training modality that is particularly useful for procedures that are technically difficult or rare. The use of simulations for educational purposes has increased dramatically over the years, with most e…
View article: The Role of Acetyl Cysteine in Cocaethylene (Non-Acetaminophen) Acute Liver Failure
The Role of Acetyl Cysteine in Cocaethylene (Non-Acetaminophen) Acute Liver Failure Open
Background. Acute liver failure can result from acetaminophen overdose, viral infection, toxins, and other disease conditions. Liver transplant is available in limited fashion and the criteria are strict as to who should get an available l…
View article: 2080 Implementing and evaluating an evidence-based intervention from the intensive care unit (ICU) setting into primary care using promotoras to reduce CA-MRSA recurrence and household transmission
2080 Implementing and evaluating an evidence-based intervention from the intensive care unit (ICU) setting into primary care using promotoras to reduce CA-MRSA recurrence and household transmission Open
OBJECTIVES/SPECIFIC AIMS: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs) recurrence ranges from 16% to 43% and presents significant challenges to clinicians, patients, and…
View article: Effect of Synthetic Cannabinoids in Older Adults
Effect of Synthetic Cannabinoids in Older Adults Open
To the Editor: Use of recreational drugs, including synthetic cannabinoids receptor agonists (SCRAs), is increasing.1, 2 Synthetic cannabinoids, known as “k2” or “spice,” contain different chemical substances combined with herbal mixtures …
View article: 2421
2421 Open
OBJECTIVES/SPECIFIC AIMS: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs) are commonly seen in primary care, with recurrence rates that range from 16% to 43%, and present s…