Roza Izgilov
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View article: Advanced glycation end-products accelerate amyloid deposits in adipocyte’s lipid droplets
Advanced glycation end-products accelerate amyloid deposits in adipocyte’s lipid droplets Open
Adipose tissue dysfunction is central to insulin resistance, and the emergence of type 2 diabetes (T2D) is associated with elevated levels of carbonyl metabolites from glucose metabolism. In this study, using methylglyoxal (MGO) and glycol…
View article: Advance Glycation End-products accelerate amyloid deposits in adipocyte’s lipid droplets
Advance Glycation End-products accelerate amyloid deposits in adipocyte’s lipid droplets Open
Adipose tissue dysfunction is central to insulin resistance, and the emergence of type 2 diabetes (T2D) is associated with elevated levels of carbonyl metabolites from glucose metabolism. In this study, using methylglyoxal (MGO) and glycol…
View article: Advanced Glycation End Products Effects on Adipocyte Niche Stiffness and Cell Signaling
Advanced Glycation End Products Effects on Adipocyte Niche Stiffness and Cell Signaling Open
Adipose tissue metabolism under hyperglycemia results in Type II diabetes (T2D). To better understand how the adipocytes function, we used a cell culture that was exposed to glycation by adding intermediate carbonyl products, which caused …
View article: Nutrition Alters the Stiffness of Adipose Tissue and Cell Signaling
Nutrition Alters the Stiffness of Adipose Tissue and Cell Signaling Open
Adipose tissue is a complex organ composed of various cell types and an extracellular matrix (ECM). The visceral adipose tissue (VAT) is dynamically altered in response to nutritional regimens that lead to local cues affecting the cells an…
View article: Exploring the Cell Stemness and the Complexity of the Adipose Tissue Niche
Exploring the Cell Stemness and the Complexity of the Adipose Tissue Niche Open
Adipose tissue is a complex organ composed of different cellular populations, including mesenchymal stem and progenitor cells, adipocytes, and immune cells such as macrophages and lymphocytes. These cellular populations alter dynamically d…