Rama Shanker Verma
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View article: Exploring Experiences, Challenges, and Preferences of University Students in Pursuing Massive Open Online Courses (MOOCs): A Descriptive Survey
Exploring Experiences, Challenges, and Preferences of University Students in Pursuing Massive Open Online Courses (MOOCs): A Descriptive Survey Open
Education in India has undergone significant transformation with technological advancements over time. Massive Open Online Courses (MOOCs) were one of those ingenuities aimed at imparting education to several students who were unable to co…
View article: Inhibition of GSK-3β Restores Differentiation Potential of Late-Passage Mesenchymal Stem Cells
Inhibition of GSK-3β Restores Differentiation Potential of Late-Passage Mesenchymal Stem Cells Open
Background/Objectives: Mesenchymal stem cells (MSCs) are regarded as a promising cell type with significant therapeutic benefits owing to their ease of isolation, maintenance, and characterisation. However, repeated passages during cultura…
View article: Biomechanical Effects of Titanium Alloy Based Single versus Dual Cage Fusion Devices
Biomechanical Effects of Titanium Alloy Based Single versus Dual Cage Fusion Devices Open
Degenerative disc disease is an increasing problematic complication following lumbar fusion surgeries. Posterior lumbar interbody fusion (PLIF) is a well-established surgical method for spine stability following intervertebral disc removal…
View article: Xanthium Strumarium based activated carbon as low cost bioadsorbent for efficient removal of antidepressant drug Imipramine
Xanthium Strumarium based activated carbon as low cost bioadsorbent for efficient removal of antidepressant drug Imipramine Open
Although, the pharmaceutical industries have contributed to improve the quality of human lifestyle. However, due to the extensive growth in living standards of modern society is one of the reasons that reinforce to millions of peoples to f…
View article: Fluid shear stress regulates the stemness of cancer cells
Fluid shear stress regulates the stemness of cancer cells Open
Fluid shear stress (FSS) has been acknowledged as an important cue in cancer development and growth. Cancer cell stemness is known to change with FSS signal. However it is not clear how the stemness changes with different orders of FSS mag…
View article: Vascular reconstruction of the decellularized biomatrix for whole-organ engineering—a critical perspective and future strategies
Vascular reconstruction of the decellularized biomatrix for whole-organ engineering—a critical perspective and future strategies Open
Whole-organ re-engineering is the most challenging goal yet to be achieved in tissue engineering and regenerative medicine. One essential factor in any transplantable and functional tissue engineering is fabricating a perfusable vascular n…
View article: Relationship between fungal bioaerosols and biotic stress on crops – A case study on wheat rust fungi
Relationship between fungal bioaerosols and biotic stress on crops – A case study on wheat rust fungi Open
This study proposes the relationship between fungal bioaerosols and biotic stress on crops using a case study on wheat leaf rust reported from northern India. We sampled and quantified the size-resolved fungal bioaerosols using the Next-Ge…
View article: Progress in Stem Cells-Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery
Progress in Stem Cells-Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery Open
Retinal pigment epithelium (RPE) is a critical cell monolayer forming the blood-retina-barrier (BRB) and a permeable bridge between the choriocapillaris and the retina. RPE is also crucial in maintaining photoreceptor function and for comp…
View article: Size-resolved genomic characterization of fungal bioaerosols with emphasis on the diversity among host-specific pathogenic and non-pathogenic fungal species
Size-resolved genomic characterization of fungal bioaerosols with emphasis on the diversity among host-specific pathogenic and non-pathogenic fungal species Open
Dispersion and atmospheric transport of fungal bioaerosols help fungal migration and colonization worldwide. The particle size of fungal propagules mainly controls this and influences the taxonomic composition of fungal bioaerosols in a re…
View article: Nitric Oxide Increases Mitomycin-C Cytotoxicity by Generation of Reactive Oxygen Species and Induces Cell Death by Apoptosis in FancC-/- Cells
Nitric Oxide Increases Mitomycin-C Cytotoxicity by Generation of Reactive Oxygen Species and Induces Cell Death by Apoptosis in FancC-/- Cells Open
Fanconi Anemia (FA) is a rare genetic disorder and patients of FA exhibit progressive bone marrow failure, developmental defects and cancer predisposition. Mitochondrial dysfunction due to oxidative stress and higher levels of Reactive Oxy…
View article: Importance of Interkingdom Interactions Among Oral Microbiome Towards Caries Development – A Review
Importance of Interkingdom Interactions Among Oral Microbiome Towards Caries Development – A Review Open
The human microbiome plays a crucial role in health and disease conditions. These microbiomes constitute a structured, coordinated microbial network throughout the human body. The oral cavity harbors one of the extensively diverse bacteria…
View article: 5FU encapsulated polyglycerol sebacate nanoparticles as anti-cancer drug carriers
5FU encapsulated polyglycerol sebacate nanoparticles as anti-cancer drug carriers Open
Diagrammatic flowchart for the synthesis of polymeric PGS and preparation of 5FU-loaded PGS nanoparticles.
View article: Nanotechnology enabled management approaches against the Covid-19 pandemic
Nanotechnology enabled management approaches against the Covid-19 pandemic Open
COVID-19 has been the causative virus for one of the biggest pandemic in human history and is still a major threat to human health after more than a year of its first incidence.Since its outbreak, it fueled a worldwide demand for the follo…
View article: Validation of copper decorated Graphene oxide material for assaying Curcumin
Validation of copper decorated Graphene oxide material for assaying Curcumin Open
Sensing has found its own place in the field of research.Novel and innovative ways to sense compounds have always been of great interest in the field of interdisciplinary sciences.The major problems observed with this wonder drug in stable…
View article: Low intermittent flow promotes rat mesenchymal stem cell differentiation in logarithmic fluid shear device
Low intermittent flow promotes rat mesenchymal stem cell differentiation in logarithmic fluid shear device Open
Bone marrow mesenchymal stem cells are an ideal candidate for bone tissue engineering due to their osteogenic potential. Along with chemical, mechanical signals such as fluid shear stress have been found to influence their differentiation …
View article: HIGH-THROUGHPUT SEQUENCING ANALYSIS OF MICROBIAL POPULATIONS IN ARCTIC ROCK SAMPLE
HIGH-THROUGHPUT SEQUENCING ANALYSIS OF MICROBIAL POPULATIONS IN ARCTIC ROCK SAMPLE Open
Recent developments in the existing molecular genetic tools have augmented our current understanding towards the deleterious effects of nanoparticles on human health. During building construction, the rapid generation of nanoparticles has …
View article: Simulated microgravity increases polyploid giant cancer cells and nuclear localization of YAP
Simulated microgravity increases polyploid giant cancer cells and nuclear localization of YAP Open
Physical cues are vital in determining cellular fate in cancer. In vitro 3D culture do not replicate forces present in vivo . These forces including tumor interstitial fluid pressure and matrix stiffness behave as switches in differentiati…
View article: Clinicopathological Analysis of HIF-1alpha and TERT on Survival Outcome in Glioblastoma Patients: A Prospective, Single Institution Study
Clinicopathological Analysis of HIF-1alpha and TERT on Survival Outcome in Glioblastoma Patients: A Prospective, Single Institution Study Open
Glioblastoma multiforme is a highly malignant and aggressive primary brain tumor with a dismal prognosis. We studied the association of immunohistochemical expression of hypoxia inducible factor-1 alpha (HIF-1α), telomerase reverse transcr…
View article: Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs
Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs Open
Mesenchymal stem cells (MSCs) have immense potential for cell-based therapy of acute and chronic pathological conditions. MSC transplantation for cell-based therapy requires a substantial number of cells in the range of 0.5–2.5 × 10 6 cell…
View article: Association of Cardiomyopathy With <i>MYBPC3</i> D389V and <i>MYBPC3<sup>Δ25bp</sup></i>Intronic Deletion in South Asian Descendants
Association of Cardiomyopathy With <i>MYBPC3</i> D389V and <i>MYBPC3<sup>Δ25bp</sup></i>Intronic Deletion in South Asian Descendants Open
MYBPC3Δ25bp/D389V is associated with hyperdynamic features, which are an early finding in hypertrophic cardiomyopathy and thought to reflect an unfavorable energetic state. These findings support that a subset of MYBPC3Δ25bp carriers, thos…
View article: Recent Advances in Induced Pluripotent Stem Cell (iPSC) based Therapeutics
Recent Advances in Induced Pluripotent Stem Cell (iPSC) based Therapeutics Open
Induced Pluripotent Stem Cells (iPSC) has revolutionized the scientific field in the last decade and our approach related to stem cells based tissue engineering/regenerative medicine for disease treatment.iPSC are cells capable of differen…
View article: Terrestrial Macrofungal Diversity from the Tropical Dry Evergreen Biome of Southern India and Its Potential Role in Aerobiology
Terrestrial Macrofungal Diversity from the Tropical Dry Evergreen Biome of Southern India and Its Potential Role in Aerobiology Open
Macrofungi have long been investigated for various scientific purposes including their food and medicinal characteristics. Their role in aerobiology as a fraction of the primary biological aerosol particles (PBAPs), however, has been poorl…