Ruanxian Dai
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View article: Proteoglycan 4 attenuates ischemic post-stroke hemorrhagic transformation and blood-brain barrier disruption
Proteoglycan 4 attenuates ischemic post-stroke hemorrhagic transformation and blood-brain barrier disruption Open
View article: GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy
GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy Open
Glucagon-like peptide-1 receptor agonists (GLP-1RAs), initially developed for type 2 diabetes and obesity, have evolved into multi-organ potential therapeutics due to their pleiotropic effects beyond glycemic control. Mechanistically, GLP-…
View article: Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics integration, and machine learning
Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics integration, and machine learning Open
Background Sepsis is a global health challenge associated with high morbidity and mortality rates. Early diagnosis and treatment are challenging because of the limited understanding of its underlying mechanisms. This study aimed to identif…
View article: Untargeted Metabolomic Analysis Using UPLC–MS/MS Reveals Metabolic Changes Associated With <i>Lanmaoa asiatica</i> Poisoning
Untargeted Metabolomic Analysis Using UPLC–MS/MS Reveals Metabolic Changes Associated With <i>Lanmaoa asiatica</i> Poisoning Open
Lanmaoa asiatica is known for its unique flavor; however, improper consumption can induce severe neuropsychiatric symptoms, including hallucinations and irritability. The underlying toxicity mechanism remains unclear, and the lack of speci…
View article: Preliminary study on the time-correlation changes in brain neurotransmitters of mice exposed to mushroom toxin ibotenic acid
Preliminary study on the time-correlation changes in brain neurotransmitters of mice exposed to mushroom toxin ibotenic acid Open
Background Mushroom poisoning represents a significant food safety issue globally, particularly neurotoxic mushroom poisoning, which raises considerable concern due to its potential to induce central nervous system symptoms. Ibotenic acid …
View article: Neuropsychiatric symptoms following the consumption of <i>Lanmaoa asiatica</i>, a poisonous mushroom native to Yunnan
Neuropsychiatric symptoms following the consumption of <i>Lanmaoa asiatica</i>, a poisonous mushroom native to Yunnan Open
Objectives To describe and analyze the clinical characteristics and outcomes of Lanmaoa asiatica poisoning cases. Methods We conducted a retrospective study of Lanmaoa asiatica poisoning cases admitted to the emergency department of the Fi…
View article: Exertional Rhabdomyolysis Combined with Acute Kidney Injury and Complicated by Posterior Reversible Encephalopathy Syndrome
Exertional Rhabdomyolysis Combined with Acute Kidney Injury and Complicated by Posterior Reversible Encephalopathy Syndrome Open
Posterior reversible encephalopathy syndrome is an uncommon syndrome in exertional rhabdomyolysis. We herein report a case of rhabdomyolysis and acute kidney injury after intense exercise. The patient also had generalized hypertension, hea…