Ruby Gao
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View article: Orai1 is a crucial downstream partner of group I metabotropic glutamate receptor signaling in dorsal horn neurons
Orai1 is a crucial downstream partner of group I metabotropic glutamate receptor signaling in dorsal horn neurons Open
Group I metabotropic glutamate receptors (group I mGluRs) have been implicated in several central nervous system diseases including chronic pain. It is known that activation of group I mGluRs results in the production of inositol triphosph…
View article: Orai1 Plays a Crucial Role in Central Sensitization by Modulating Neuronal Excitability
Orai1 Plays a Crucial Role in Central Sensitization by Modulating Neuronal Excitability Open
Pathological pain is a common and debilitating condition that is often poorly managed. Central sensitization is an important mechanism underlying pathological pain. However, candidate molecules involved in central sensitization remain uncl…
View article: A store‐operated calcium channel inhibitor attenuates collagen‐induced arthritis
A store‐operated calcium channel inhibitor attenuates collagen‐induced arthritis Open
Background and Purpose Store‐operated calcium ( SOC ) channels are thought to play a critical role in immune responses, inflammatory diseases and chronic pain. The aim of this study was to explore the potential role and mechanisms of SOC c…