Ruby N. Huynh
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View article: Mueller matrix polarimetry and polar decomposition of articular cartilage imaged in reflectance
Mueller matrix polarimetry and polar decomposition of articular cartilage imaged in reflectance Open
Articular cartilage birefringence relates to zonal architecture primarily of type II collagen, which has been assessed extensively in transmission, through thin tissue sections, to evaluate cartilage repair and degeneration. Mueller matrix…
View article: Pulsed focused ultrasound lowers interstitial fluid pressure and increases nanoparticle delivery and penetration in head and neck squamous cell carcinoma xenograft tumors
Pulsed focused ultrasound lowers interstitial fluid pressure and increases nanoparticle delivery and penetration in head and neck squamous cell carcinoma xenograft tumors Open
Nanocarriers offer a promising approach to significantly improve therapeutic delivery to solid tumors as well as limit the side effects associated with anti-cancer agents. However, their relatively large size can negatively affect their ab…
View article: Microstructural densification and alignment by aspiration‐ejection influence cancer cell interactions with three‐dimensional collagen networks
Microstructural densification and alignment by aspiration‐ejection influence cancer cell interactions with three‐dimensional collagen networks Open
Extracellular matrix microstructure and mechanics are crucial to breast cancer progression and invasion into surrounding tissues. The peritumor collagen network is often dense and aligned, features which in vitro models lack. Aspiration of…
View article: Polarized reflectance from articular cartilage depends upon superficial zone collagen network microstructure
Polarized reflectance from articular cartilage depends upon superficial zone collagen network microstructure Open
Polarized reflectance from articular cartilage involves light scattering dependent on surface features, sub-surface optical properties, and collagen birefringence. To understand how surface roughness, zonal collagen microstructure, and cho…
View article: Noninvasive assessment of articular cartilage surface damage using reflected polarized light microscopy
Noninvasive assessment of articular cartilage surface damage using reflected polarized light microscopy Open
Articular surface damage occurs to cartilage during normal aging, osteoarthritis, and in trauma. A noninvasive assessment of cartilage microstructural alterations is useful for studies involving cartilage explants. This study evaluates pol…