Ruby Thapa
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View article: Electrochemical breath profiling for early thoracic malignancy screening
Electrochemical breath profiling for early thoracic malignancy screening Open
Lung cancer remains a leading cause of cancer death globally and affects millions of lives across the globe. Early detection of lung cancer significantly improves survival rates. Screening with low-dose CT scans for high-risk individuals c…
View article: An opportunistic pathogen under stress: how Group B <i>Streptococcus</i> responds to cytotoxic reactive species and conditions of metal ion imbalance to survive
An opportunistic pathogen under stress: how Group B <i>Streptococcus</i> responds to cytotoxic reactive species and conditions of metal ion imbalance to survive Open
Group B Streptococcus (GBS; also known as Streptococcus agalactiae) is an opportunistic bacterial pathogen that causes sepsis, meningitis, pneumonia, and skin and soft tissue infections in neonates and healthy or immunocompromised adults. …
View article: Alterations in cell arrangements of group B streptococcus due to virulence factor expression can bias estimates of bacterial populations based on colony count measures
Alterations in cell arrangements of group B streptococcus due to virulence factor expression can bias estimates of bacterial populations based on colony count measures Open
Group B streptococcus (GBS) is a chain-forming commensal bacterium and opportunistic pathogen that resides in the gastrointestinal and genitourinary tract of healthy adults. GBS can cause various infections and related complications in pre…
View article: Utility of a Mycobacterium leprae molecular viability assay for clinical leprosy: An analysis of cases from the Philippines, Ethiopia, and Nepal
Utility of a Mycobacterium leprae molecular viability assay for clinical leprosy: An analysis of cases from the Philippines, Ethiopia, and Nepal Open
Mycobacterium leprae is a slow-growing species of mycobacteria that cannot be cultured in axenic media. This presents a number of challenges for monitoring treatment efficacy and advancing new drugs and regimens for treating leprosy. We pr…
View article: Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract
Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract Open
Streptococcus agalactiae glyceraldehyde 3-phosphate dehydrogenase (GAPDH), encoded by gapC, is a glycolytic enzyme that is associated with virulence and immune-mediated protection. However, the role of GAPDH in cellular cytokine responses …
View article: Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy
Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy Open
In our study, 35% of RFT patients had ongoing NP. Risk factors include nerve tenderness and reaction. They suffer from more daily life interference and psychological distress. Leprosy patient care should include recognition and management …