Ruchika Kumari
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View article: The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion
The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion Open
Autophagy is a crucial intracellular pathway for maintaining cellular homeostasis. It involves forming double-membrane vesicles called autophagosomes, which deliver cytosolic cargoes to the lysosomes/vacuoles for degradation. Biogenesis of…
View article: An Update on the Nutritional and Therapeutic Potential of <scp><i>Dioscorea oppositifolia</i></scp>
An Update on the Nutritional and Therapeutic Potential of <span><i>Dioscorea oppositifolia</i></span> Open
Dioscorea oppositifolia L., also known as Cinnamon vine, has a longstanding history in traditional medicine due to its diverse bioactive compounds. However, comprehensive scientific evaluations of its phytochemical properties and therapeut…
View article: Uncovering the Mechanisms of <i>Angelica glauca</i> Edgew. In Breast Cancer: A Combined In Vitro and In Silico Approach
Uncovering the Mechanisms of <i>Angelica glauca</i> Edgew. In Breast Cancer: A Combined In Vitro and In Silico Approach Open
Angelica glauca Edgew. is a medicinal herb native to the Himalayan region, renowned for its significant therapeutic potential and traditional use in treating various ailments. However, it has not been extensively investigated with pertinen…
View article: Quantitative ethnobotanical study of medicinal plants used by native people of selected areas of Chhota Bhangal, Himachal Pradesh
Quantitative ethnobotanical study of medicinal plants used by native people of selected areas of Chhota Bhangal, Himachal Pradesh Open
Background: Ethnobotanical information about medicinal plants and their indigenous uses plays a major role in the conservation of biodiversity and cultural traditions. The native people of Chhota Bhangal hold the traditional knowledge and …
View article: Greasy cutworm (<i>Agrotis ipsilon</i>) and its biorational management strategies: A review
Greasy cutworm (<i>Agrotis ipsilon</i>) and its biorational management strategies: A review Open
Agrotis ipsilon (Lepidoptera:Noctuidae) known as greasy cutworm is an important destructive polyphagous pest of many crops distributed throughout the world. Larvae are polyphagous with a wide and diverse host range, as a result of which th…
View article: Mechanistic role and potential of Ayurvedic herbs as anti-aging therapies
Mechanistic role and potential of Ayurvedic herbs as anti-aging therapies Open
Introduction Medicinal plants and herbs are the most important part of the Ayurveda. The term Rasayana in Charaka Samhita confers long life, youthfulness, strong body, freedom from diseases and the plants mentioned in Rsayana possess antia…
View article: A review on mitigation of various ailments via a bioactive component of Tribulus terrestris L. - A medicinally important herb
A review on mitigation of various ailments via a bioactive component of Tribulus terrestris L. - A medicinally important herb Open
Background: Tribulus terrestris L. is an important traditional therapeutic plant that has been utilized for multiple purposes since the Vedic period and belong to Zygophyllaceae family. It is distributed in sub-tropical regions including I…
View article: Exocyst Subcomplex Functions in Autophagosome Biogenesis by Regulating Atg9 Trafficking
Exocyst Subcomplex Functions in Autophagosome Biogenesis by Regulating Atg9 Trafficking Open
During autophagy, double-membrane vesicles called autophagosomes capture and degrade the intracellular cargo. The de novo formation of autophagosomes requires several vesicle transport and membrane fusion events which are not completely un…
View article: 240 Implementation of a reduced rituximab maintenance regimen for patients with rheumatoid arthritis
240 Implementation of a reduced rituximab maintenance regimen for patients with rheumatoid arthritis Open
Background: Rituximab (RTX), a monoclonal anti-CD20 B-cell depleting antibody, is a treatment option in severe active rheumatoid arthritis (RA).Maintenance regimes for RTX in RA are debated with trials of ultra-low RTX protocols while the …