Ruchir Singh
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View article: P114 Medication adherence to b/tsDMARDS remains sub-optimal in refractory rheumatoid arthritis
P114 Medication adherence to b/tsDMARDS remains sub-optimal in refractory rheumatoid arthritis Open
Background/Aims Difficult-to-treat rheumatoid arthritis (D2T-RA) is defined by poor treatment responses to multiple biological or targeted synthetic disease modifying anti-rheumatic drugs (b/tsDMARDs). The factors underlying treatment fail…
View article: Occurrence, Virulence and Drug Resistance Characterization of Non-typhoidal Salmonella in Poultry and Environmental Samples of Rewa City, India
Occurrence, Virulence and Drug Resistance Characterization of Non-typhoidal Salmonella in Poultry and Environmental Samples of Rewa City, India Open
The Experiment was conducted during June–December, 2022 at Department of Veterinary Public Health & Epidemiolgy, College of Veterinary Science & Animal Husbandry, Rewa, NDVSU, Jabalpur, M.P. India. to attribute the possible risk of poultry…
View article: Targeting contributory factors in difficult-to-treat rheumatoid arthritis
Targeting contributory factors in difficult-to-treat rheumatoid arthritis Open
Despite recent advances with the introduction of biologic/targeted synthetic disease modifying anti-rheumatic drugs (b/tsDMARDs); there is a growing number of individuals with rheumatoid arthritis (RA) in whom stepwise escalation of curren…
View article: Evaluation of different transport media for survival of H5N1 highly pathogenic avian influenza virus.
Evaluation of different transport media for survival of H5N1 highly pathogenic avian influenza virus. Open
In the case of the H5N1 avian influenza outbreak, specific detection is critical for the timely implementation of control and preventive measures to limit the spread of the disease. Sample collection, storage, and transportation are critic…
View article: OA04 Association of clinical and demographic factors with quality of life, functional status, depression, and fatigue in patients presenting with, and at risk of, rheumatoid arthritis
OA04 Association of clinical and demographic factors with quality of life, functional status, depression, and fatigue in patients presenting with, and at risk of, rheumatoid arthritis Open
Background/Aims Rheumatoid arthritis (RA) is often preceded by symptomatic phases during which classification criteria are not fulfilled. The health burden of these “at-risk” stages is not well described. This study assessed health-related…
View article: Is symptom duration before DMARD therapy a determinant of direct and indirect costs in DMARD-naïve RA patients? A systematic review
Is symptom duration before DMARD therapy a determinant of direct and indirect costs in DMARD-naïve RA patients? A systematic review Open
Objective Early treatment of RA improves clinical outcomes; however, the impact on health economic outcomes is unclear. This review sought to investigate the relationship between symptom/disease duration and resource utilization/costs and …
View article: The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis
The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis Open
Objectives The value of US-defined tenosynovitis in predicting the persistence of inflammatory arthritis is not well described. In particular, the predictive utility of US-defined tenosynovitis of larger tendons is yet to be reported. We a…
View article: Fibroblast pathology in inflammatory joint disease
Fibroblast pathology in inflammatory joint disease Open
Rheumatoid arthritis is an immune‐mediated inflammatory disease in which fibroblasts contribute to both joint damage and inflammation. Fibroblasts are a major cell constituent of the lining of the joint cavity called the synovial membrane.…
View article: The importance of skin biopsies: Sweet syndrome as a differential for 'acute painful red rash’ in a patient with normal neutrophils and polymyalgia rheumatica on glucocorticoids
The importance of skin biopsies: Sweet syndrome as a differential for 'acute painful red rash’ in a patient with normal neutrophils and polymyalgia rheumatica on glucocorticoids Open
Cutaneous lesions and skin rashes are commonly encountered on the acute take in acute medical units. Sweet syndrome (SS) is an uncommon inflammatory disorder, originally described as 'acute febrile neutrophilic dermatosis' by Sweet.[1][1] …
View article: New headaches with normal inflammatory markers: an early atypical presentation of giant cell arteritis
New headaches with normal inflammatory markers: an early atypical presentation of giant cell arteritis Open
An 80-year-old man presented repeatedly to his general practitioner with 3 months of unexplained persistent frontal headaches. CT head revealed no diagnosis. His dentist diagnosed his co-existing jaw pain as bruxism. Three months later, th…
View article: The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development
The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development Open
US-defined digit flexor TS provided independent predictive data for persistent RA development in patients with early arthritis. The predictive utility of this tendon site should be further assessed in a larger cohort; investigators designi…
View article: Silent HIV infection masquerading behind psoriasis
Silent HIV infection masquerading behind psoriasis Open
Psoriasis is a chronic inflammatory autoimmune skin disease characterized by immune-mediated cutaneous inflammation and keratinocyte hyperproliferation. Psoriasis can be the early presenting cutaneous manifestation in patients with human i…