Rudolf Reiter
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View article: Seeing the Invisible Resiliency (STIR): Chronic Autoimmune Conditions and Post‐Secondary Education Experiences in Young Adulthood
Seeing the Invisible Resiliency (STIR): Chronic Autoimmune Conditions and Post‐Secondary Education Experiences in Young Adulthood Open
Introduction Young adults with chronic autoimmune conditions face unique and often overlooked challenges in post‐secondary education due to the invisible and unpredictable nature of these conditions. This patient‐led qualitative study aims…
View article: Impact of HPV Status and AurkA Phe31Ile Polymorphism on The Response to Cetuximab Treatment of Head and Neck Squamous Cell Carcinoma (HNSCC) Patients
Impact of HPV Status and AurkA Phe31Ile Polymorphism on The Response to Cetuximab Treatment of Head and Neck Squamous Cell Carcinoma (HNSCC) Patients Open
Background: Since 2004, the use of the monoclonal antibody cetuximab has been preferred over platinum-based therapy for patients with advanced Head and neck squamous cell carcinoma (HNSCC). However, the response rate to the treatment is on…
View article: Subglottische Pathologien
Subglottische Pathologien Open
Zusammenfassung Subglottische Pathologien sind sehr selten und manifestieren sich mit einem unspezifischen klinischen Erscheinungsbild in Form einer Gewebevermehrung auf Höhe des Ringknorpels bzw. der cranialen Trachea, was die Diagnose ve…
View article: Bradykinin Receptor B1 and C-Reactive Protein as Prognostic Factors for Pharyngocutaneous Fistula Development After Laryngectomy
Bradykinin Receptor B1 and C-Reactive Protein as Prognostic Factors for Pharyngocutaneous Fistula Development After Laryngectomy Open
View article: The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma
The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma Open
Recently the Aurora-Kinases (Aurk) moved into the focus as novel disease related biomarkers and therapeutic targets. Elevated Aurora-Kinase expression has been found in a number of malignancies, amongst them HNSCC. For esophageal cancer, t…
View article: Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation
Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation Open
EGFRvIII can be detected in HNSCC patient samples. Nevertheless, the low prevalence and similar response rates to targeted drugs and irradiation in vitro cast doubt regarding the clinical relevance of EGFRvIII in HNSCC.
View article: HES1 mRNA expression is associated with survival in sinonasal squamous cell carcinoma
HES1 mRNA expression is associated with survival in sinonasal squamous cell carcinoma Open
View article: Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate
Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate Open
View article: Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative Gene
Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative Gene Open
Nonsyndromic orofacial clefts are common birth defects with multifactorial etiology. The most common type is cleft lip, which occurs with or without cleft palate (nsCLP and nsCLO, respectively). Although genetic components play an importan…
View article: In Reply
In Reply Open
Hoarseness Caused by GlucocorticoidsReversible hoarseness, which may occur after systemic administration of glucocorticoids, is not included in the list of causes of dysphonia provided by the authors (1).In my experience, patients already …
View article: HNSCC cells resistant to EGFR pathway inhibitors are hypermutated and sensitive to DNA damaging substances.
HNSCC cells resistant to EGFR pathway inhibitors are hypermutated and sensitive to DNA damaging substances. Open
Despite remarkable successes with targeted therapies in the treatment of cancer, resistance can occur which limits the clinical outcome. In this study, we generated and characterized resistant cell clones derived from two different head an…
View article: Epstein-Barr virus infection is strictly associated with the metastatic spread of sinonasal squamous-cell carcinomas
Epstein-Barr virus infection is strictly associated with the metastatic spread of sinonasal squamous-cell carcinomas Open
View article: Hoarseness
Hoarseness Open
Voice therapy, vocal cord surgery, and drug therapy for appropriate groups of patients with hoarseness are well documented as effective by the available evidence. In patients with risk factors, especially smokers, hoarseness should be imme…
View article: Selective inhibition of EGFR downstream signaling reverses the irradiation-enhanced migration of HNSCC cells.
Selective inhibition of EGFR downstream signaling reverses the irradiation-enhanced migration of HNSCC cells. Open
Irradiation, which is one of the standard therapies used to treat squamous cell carcinoma of the head and neck (HNSCC), has been linked to enhanced tumor migration in carcinomas. In this study, we demonstrated that irradiation induced the …