Explanipedia

Prolonged thrombocytopenia following diverse CAR-T cell therapies: High incidence, inflammatory risk factors, and a comparative efficacy analysis of TPO-receptor agonist strategies in a real-world cohort Open

Peihao Zheng, Rui-Jie He, Fangfang Cheng, Yajing Zhang · 2025

Background: Prolonged thrombocytopenia (PT) is a major toxicity following chimeric antigen receptor (CAR) T-cell therapy, increasing hemorrhagic risk and limiting subsequent treatments. The etiology is complex, extending beyond lymphodeple…

Glycosidic Phenylpropanoid Dimers and Trimers from Castanopsis Choboensis and Their Anti-Inflammatory Activities Open

Nao Pang, Ya-Feng Wang, Shuyao Li, Guiqin Li, Ge Li , et al. · 2025

Megaphyllanins A–I, triterpenoid galloyl and hexahydroxydiphenoyl esters with α-glucosidase inhibitory activity from Castanopsis megaphylla Hu Open

Rui-Jie He, Zhang-Bin Liu, Kedi Yang, Ge Li, Yong‐Lin Huang · 2025

Isolation of Two New Phenolic Glycosides from Castanopsis chinensis Hance by Combined Multistep CC and HSCCC Separation and Evaluation of Their Antioxidant Activity Open

Ya-Feng Wang, Ping Lin, Yong‐Lin Huang, Rui-Jie He, Bing-Yuan Yang , et al. · 2023

The characteristics of high polarity and susceptibility to oxidation in phenolic glycosides increase the difficulty of their separation from natural products. In the present study, two new phenolic glycosides with similar structures were i…

Triterpenoids from the Leaves of Cyclocarya paliurus and Their Glucose Uptake Activity in 3T3-L1 Adipocytes Open

Xiaoqin Liang, Shengping Deng, Yan Huang, Liwei Pan, Yanling Chang , et al. · 2023

Four new dammarane triterpenoid saponins cypaliurusides Z1–Z4 (1–4) and eight known analogs (5–12) were isolated from the leaves of Cyclocarya paliurus. The structures of the isolated compounds were determined using a comprehensive analysi…

The complete chloroplast genome sequence of <i>Castanopsis fordii</i> Hance (Fagaceae) Open

Ya-Feng Wang, Yong‐Lin Huang, Rui-Jie He, Bing-Yuan Yang, Zhang-Bin Liu · 2023

Castanopsis fordii Hance 1884 is a typical evergreen broad-leaved forest plant in the south subtropical and middle subtropical regions of China. It has high utilization value in wood production and soil erosion protection. Here, we …

Two Novel Butyrolactone Lignan Dimers from Leaves of Chastanopsis Chinensis and Their Anti-Inflammatory Activities Open

Ping Lin, Ya-Feng Wang, Bing-Yuan Yang, Rui-Jie He, Meng Li , et al. · 2023

Structural Characterization and Assessment of Anti-Inflammatory Activities of Polyphenols and Depsidone Derivatives from Melastoma malabathricum subsp. normale Open

Rui-Jie He, Ya-Feng Wang, Bing-Yuan Yang, Zhang-Bin Liu, Dianpeng Li , et al. · 2022

The roots of Melastoma malabathricum subsp. normale (D. Don) Karst. Mey have been used in traditional ethnic medicine systems in China to treat inflammation-triggered ailments, such as trauma, toothache, and fever. Therefore, the aim of th…

Structural Characterization and Assessment of Anti-Inflammatory and Anti-Tyrosinase Activities of Polyphenols from Melastoma normale Open

Rui-Jie He, Jun Li, Yong‐Lin Huang, Ya-Feng Wang, Bing-Yuan Yang , et al. · 2021

Polyphenols, widely distributed in the genus Melastoma plants, possess extensive cellular protective effects such as anti-inflammatory, anti-tyrosinase, and anti-obesity, which makes it a potential anti-inflammatory drug or enzyme inhibito…

Data for: Discovery of Anti-inflammatory Terpenoids from Mallotus conspurcatus Open

Jun Li, Rui‐Yun Yang, Zhengmin Yang, Yanjun Zhang, Xishan Huang , et al. · 2018

NMR and HRESIMS spectra of the new compounds malloconspur A (1) and malloconspur B (2)

Two New Galloyl Glucosides from the Leaves of Castanopsis fordii Open

Yong‐Lin Huang, Kedi Yang, Zhang-Bin Liu, Ya-Feng Wang, Li Ge , et al. · 2018

Castanopsis is a genus belonging to the Fagaceae family.In previous studies, the main of the secondary metabolites from Castanopsis were found to be tannins and related compounds, 1-5 including polyphenols and flavonoids from C. fordii. 6,…

Two New Galloyl Glucosides from the Bark of Castanopsis fargesiI Open

Yong Lin Huang, Ya-Feng Wang, Jinlei Liu, Rui-Jie He, Xiaojie Yan , et al. · 2017

In a continuing phytochemical investigation of the Castanopsis species (Fagaceae), two new galloyl glucosides, 5-O-β-D-(6'-O-galloyl)glucopyranosyl pyran-2-one (1) and 4-hydroxymethyl-2-methoxyphenol 1-O-β-D-(6'-O-galloyl)glucoside (2), we…

A new flavane acid from the fruits of <i>Illicium verum</i> Open

Liangdeng Wu, Chun-Lan Xiong, Zizhan Chen, Rui-Jie He, Yanjun Zhang , et al. · 2016

A new compound, illiciumflavane acid (1), along with 13 known compounds (2–14), were isolated from the fruits of Illicium verum Hook. F. Their structures were elucidated through various spectroscopic methods, including 1D NMR…

CCDC 1471448: Experimental Crystal Structure Determination Open

Rui-Jie He, Xishan Huang, Yanjun Zhang, Liangdeng Wu, Hui Nie , et al. · 2016

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

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