Ruijing Chen
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View article: Bifidobacterium animalis subsp. lactis A6 ameliorates bone and muscle loss via modulating gut microbiota composition and enhancing butyrate production
Bifidobacterium animalis subsp. lactis A6 ameliorates bone and muscle loss via modulating gut microbiota composition and enhancing butyrate production Open
Systematic bone and muscle loss is a complex metabolic disease, which is frequently linked to gut dysfunction, yet its etiology and treatment remain elusive. While probiotics show promise in managing diseases through microbiome modulation,…
View article: Histone deacetylase inhibition enhances extracellular vesicles from muscle to promote osteogenesis via miR-873-3p
Histone deacetylase inhibition enhances extracellular vesicles from muscle to promote osteogenesis via miR-873-3p Open
Regular physical activity is widely recognized for reducing the risk of various disorders, with skeletal muscles playing a key role by releasing biomolecules that benefit multiple organs and tissues. However, many individuals, particularly…
View article: Mitochondrial transfer - a novel promising approach for the treatment of metabolic diseases
Mitochondrial transfer - a novel promising approach for the treatment of metabolic diseases Open
Metabolic disorders remain a major global health concern in the 21st century, with increasing incidence and prevalence. Mitochondria play a critical role in cellular energy production, calcium homeostasis, signal transduction, and apoptosi…
View article: Ghost messages: cell death signals spread
Ghost messages: cell death signals spread Open
Cell death is a mystery in various forms. Whichever type of cell death, this is always accompanied by active or passive molecules release. The recent years marked the renaissance of the study of these molecules showing they can signal to a…
View article: A Global Phosphorylation Atlas of Proteins Within Pathological Site of Rotator Cuff Tendinopathy
A Global Phosphorylation Atlas of Proteins Within Pathological Site of Rotator Cuff Tendinopathy Open
Rotator cuff tendinopathy (RCT) is the most common cause of shoulder pain, therefore posing an important clinical problem. Understanding the mechanism and biochemical changes of RCT would be of crucial importance and pave the path to targe…
View article: A higher expression of P2X7 receptor at the site of heterotopic ossification promotes osteogenesis
A higher expression of P2X7 receptor at the site of heterotopic ossification promotes osteogenesis Open
Background Heterotopic ossification (HO) refers to a painful and complex disease. Adenosine triphosphate (ATP), as a key modulator of inflammation, is verified to promote the development of HO. However, the mechanism remains to be illustra…