Ruili Zhang
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View article: Advances in Optical Techniques for Tumor Detection
Advances in Optical Techniques for Tumor Detection Open
The critical importance of early cancer detection in improving patient survival rates has driven substantial innovation in diagnostic methodologies. Optical detection technologies, renowned for their superior sensitivity, molecular specifi…
View article: Porous Carbon-Modified Silk-Derived Carbon Mesh for High-Performance Transparent All-Solid Supercapacitors
Porous Carbon-Modified Silk-Derived Carbon Mesh for High-Performance Transparent All-Solid Supercapacitors Open
The practical application of transparent supercapacitors (TSCs) is limited by the inherent trade-off between transparency and conductivity, as well as the environmental and economic drawbacks of electrode materials. This study presents a n…
View article: A pyroptosis proportion tunable nano-modulator for cancer immunotherapy
A pyroptosis proportion tunable nano-modulator for cancer immunotherapy Open
Rationale: Pyroptosis, a form of programmed cell death mediated by gasdermin proteins, holds significant potential in cancer immunotherapy. However, precise control of pyroptosis in cancer cells is essential to avoid biosafety conce…
View article: Compton scattering X-ray imaging system for material detection through 3 mm aluminum shielding for potential future space application
Compton scattering X-ray imaging system for material detection through 3 mm aluminum shielding for potential future space application Open
This paper explores the application of Compton scattering imaging for the active detection of space debris at long distances and through dense metallic shielding. Unlike conventional short-range applications in security screening, space-ba…
View article: Porous Carbon Modified Silk-Derived Carbon Mesh for High Performance Transparent All-Solid Supercapacitors
Porous Carbon Modified Silk-Derived Carbon Mesh for High Performance Transparent All-Solid Supercapacitors Open
The practical application of transparent supercapacitors (TSCs) is limited by the inherent trade-off between transparency and conductivity, as well as the environmental and economic drawbacks of electrode materials. This study presents a n…
View article: Programmable Bacterial Architects Crafting Sonosensitizers for Tumor‐Specific Sonodynamic Immunotherapy
Programmable Bacterial Architects Crafting Sonosensitizers for Tumor‐Specific Sonodynamic Immunotherapy Open
Sonodynamic therapy (SDT) is a non‐invasive cancer treatment that uses ultrasound to activate sonosensitizers for selective tumor ablation. With its superior tissue penetration compared to photodynamic therapy, SDT demonstrates the potenti…
View article: Rapid, label-free detection of colorectal cancer with an aberration-free line scanning confocal Raman imager
Rapid, label-free detection of colorectal cancer with an aberration-free line scanning confocal Raman imager Open
A self-developed aberration-free line scanning confocal Raman imager (AFLSCRI) with a spectral resolution of 0.12 nm and a spatial resolution of 2 μm is utilized to diagnose colorectal cancer. The tissues were categorized into four subgrou…
View article: Effective Numerical Simulation of Fault Transient System
Effective Numerical Simulation of Fault Transient System Open
Power systems, including synchronous generator systems, are typical systems that strive for stable operation. In this article, we numerically study the fault transient process of a synchronous generator system based on the first benchmark …
View article: A Spatiotemporal Tunable Filter Array Chip for Video-Rate Hyperspectral Imaging
A Spatiotemporal Tunable Filter Array Chip for Video-Rate Hyperspectral Imaging Open
Existing miniaturized spectral imagers have mutual restrictions among spatial, temporal, and spectral resolutions, making them inadequate to meet practical needs. Here, we demonstrate a spatiotemporal filter array chip to tackle the trade-…
View article: Correction: CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer
Correction: CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer Open
View article: Power-tunable multicolor upconversion in nanocrystals under single-wavelength excitation
Power-tunable multicolor upconversion in nanocrystals under single-wavelength excitation Open
In this work, we demonstrate for the first time tunable upconversion luminescence in three primary colors using a single excitation wavelength of 980 nm, via altering the excitation intensity.
View article: Toward a 10-W level femtosecond erbium laser operating in the 1600 nm low gain region
Toward a 10-W level femtosecond erbium laser operating in the 1600 nm low gain region Open
1.6 µm ultrafast lasers are important in biomedical applications because the wavelength is located within an attractive biological window called the near-infrared-II (NIR-II) region. However, for erbium- or thulium-doped fibers, 1.6 μm is …
View article: A GAN Guided NCCT to CECT Synthesis With an Advanced CNN-Transformer Aggregated Generator
A GAN Guided NCCT to CECT Synthesis With an Advanced CNN-Transformer Aggregated Generator Open
Computed tomography (CT) is essential for diagnosing and managing various diseases, with contrast-enhanced CT (CECT) offering higher contrast images following contrast agent injection. Nevertheless, the usage of contrast agents may cause s…
View article: Unveiling the Activation Mechanism of V4+/V5+ Redox in Transition Metal-Doped Na3v2(Po4)3 for High-Voltage Sodium-Ion Batteries
Unveiling the Activation Mechanism of V4+/V5+ Redox in Transition Metal-Doped Na3v2(Po4)3 for High-Voltage Sodium-Ion Batteries Open
View article: RETRACTED ARTICLE: CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer
RETRACTED ARTICLE: CKS2 induces autophagy-mediated glutathione metabolic reprogramming to facilitate ferroptosis resistance in colon cancer Open
Background Ferroptosis, a form of cell death characterized by lipid peroxidation, plays a crucial role in tumor suppression, offering novel avenues for cancer therapy. Previous studies have indicated that high levels of cyclin-dependent ki…
View article: Proton nanomodulators for enhanced Mn2+-mediated chemodynamic therapy of tumors via HCO3− regulation
Proton nanomodulators for enhanced Mn2+-mediated chemodynamic therapy of tumors via HCO3− regulation Open
This work addresses the challenge of insufficient HCO3- in the TME for Mn2+-mediated Fenton catalysts and could provide a promising strategy for designing high-performance Mn2+-mediated CDT agent…
View article: Miniaturized Hyperspectral Imager Utilizing a Reconfigurable Filter Array for Both High Spatial and Spectral Resolutions
Miniaturized Hyperspectral Imager Utilizing a Reconfigurable Filter Array for Both High Spatial and Spectral Resolutions Open
Miniaturized hyperspectral imaging based on filter arrays has attracted much attention in consumer applications, such as food safety and biomedical applications. In this Letter, we demonstrate a miniaturized hyperspectral imager using a re…
View article: Real-time detection and resection of sentinel lymph node metastasis in breast cancer through a rare earth nanoprobe based NIR-IIb fluorescence imaging
Real-time detection and resection of sentinel lymph node metastasis in breast cancer through a rare earth nanoprobe based NIR-IIb fluorescence imaging Open
Sentinel lymph node (SLN) biopsy is a commonly employed procedure for the routine assessment of axillary involvement in patients with breast cancer. Nevertheless, conventional SLN mapping cannot reliably distinguish the presence and absenc…
View article: Light‐Activated In Situ Vaccine with Enhanced Cytotoxic T Lymphocyte Infiltration and Function for Potent Cancer Immunotherapy
Light‐Activated In Situ Vaccine with Enhanced Cytotoxic T Lymphocyte Infiltration and Function for Potent Cancer Immunotherapy Open
In situ cancer vaccination is an attractive strategy that stimulates protective antitumor immunity. Cytotoxic T lymphocytes (CTLs) are major mediators of the adaptive immune defenses, with critical roles in antitumor immune response and es…
View article: Proton Nanomodulators for Enhanced Mn 2+ -mediated Chemodynamic Therapy of Tumors via HCO 3 − Regulation
Proton Nanomodulators for Enhanced Mn 2+ -mediated Chemodynamic Therapy of Tumors via HCO 3 − Regulation Open
Background Mn2+-mediated chemodynamic therapy (CDT) has been emerged as a promising cancer therapeutic modality that relies heavily on HCO3− level in the system. Although the physiological buffers (H2<…
View article: Improve the Efficiency of Organic Solar Cells by Creating a Favorable Charge Transport Channel with a Halogen-Free Additive
Improve the Efficiency of Organic Solar Cells by Creating a Favorable Charge Transport Channel with a Halogen-Free Additive Open
View article: Nanosecond pulse X-ray emission source based on ultrafast laser modulation
Nanosecond pulse X-ray emission source based on ultrafast laser modulation Open
In response to the growing demand for miniaturized ultrafast pulsed X-ray sources in the fields of fundamental science and space applications, we design and develop an ultrafast pulsed X-ray generator based on a laser-modulated light sourc…
View article: Iron-based metal-organic framework co-loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo-ferrotherapy via sustainable glutathione elimination
Iron-based metal-organic framework co-loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo-ferrotherapy via sustainable glutathione elimination Open
Background Emerging ferroptosis-driven therapies based on nanotechnology function either by increasing intracellular iron level or suppressing glutathione peroxidase 4 (GPX4) activity. Nevertheless, the therapeutic strategy of simultaneous…
View article: Advances in Synthesis Strategies for Lanthanide-based NaYF4 Upconversion Nanocrystals and Their Applications in Ratiometric Thermometry
Advances in Synthesis Strategies for Lanthanide-based NaYF4 Upconversion Nanocrystals and Their Applications in Ratiometric Thermometry Open
The optical characteristics and varied applications of lanthanide-doped NaYF4 upconversion nanocrystals have received considerable interest in recent years, such as in ratiometric thermometry.This review thoroughly examines the various syn…
View article: Sonodynamic-immunomodulatory nanostimulators activate pyroptosis and remodel tumor microenvironment for enhanced tumor immunotherapy
Sonodynamic-immunomodulatory nanostimulators activate pyroptosis and remodel tumor microenvironment for enhanced tumor immunotherapy Open
Rationale: Spatiotemporal control of pyroptosis has a profound impact on cancer immunotherapy. Owing to the precise spatiotemporal control and reduction in the side effects of ultrasound (US), sonodynamic therapy (SDT) is expected t…
View article: The Role of Relative Deprivation and Attribution Style in the Relationship between Organizational Fairness and Employees’ Service Innovation Behavior
The Role of Relative Deprivation and Attribution Style in the Relationship between Organizational Fairness and Employees’ Service Innovation Behavior Open
The basis of organizational innovation is employee innovation, which is of great significance for organizations to gain a competitive advantage. At present, the research on the influencing factors of employee service innovation behavior is…
View article: Genetically engineered macrophage membrane-coated nanoparticles for enhanced tumor targeting and synergistic cancer therapy
Genetically engineered macrophage membrane-coated nanoparticles for enhanced tumor targeting and synergistic cancer therapy Open
The poor targeting capability of systemically administered drugs is a major hurdle in designing effective therapies with minimal off-target side effects. Here, as a proof of concept, we propose a genetic engineering strategy to embed a pro…
View article: Redox dyshomeostasis modulation of the tumor intracellular environment through a metabolic intervention strategy for enhanced photodynamic therapy
Redox dyshomeostasis modulation of the tumor intracellular environment through a metabolic intervention strategy for enhanced photodynamic therapy Open
Rationale: Photodynamic therapy (PDT) is a clinically approved anticancer treatment with a promising therapeutic prospect, however, usually suffers from the unfavorable intracellular environment including cellular hypoxia and excess…
View article: Insights into the electrochemical performance of metal fluoride cathodes for lithium batteries
Insights into the electrochemical performance of metal fluoride cathodes for lithium batteries Open
In recent years, energy storage and conversion have become key areas of research to address social and environmental issues, as well as practical applications, such as increasing the storage capacity of portable electronic storage devices.…
View article: A visible light photon-counting imaging detector based on induction readout
A visible light photon-counting imaging detector based on induction readout Open
Photon-counting imaging detectors based on microchannel plate (MCP) and position-sensitive anode are characterized by extremely high sensitivity, as well as the ability to detect single photons. In this study, a visible light photon-counti…