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View article: A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors
A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors Open
Antibody–drug conjugates (ADCs) have transformed cancer therapy but remain limited by their dependence on internalizing antigens, poor applicability to untargetable tumors, and susceptibility to drug resistance. Therefore, a modular antimi…
View article: Enhancing the selectivity and conditional sensitivity of an antimicrobial peptide through cleavage simulations and homoarginine incorporation to combat drug-resistant bacteria
Enhancing the selectivity and conditional sensitivity of an antimicrobial peptide through cleavage simulations and homoarginine incorporation to combat drug-resistant bacteria Open
Antimicrobial peptides (AMPs) are considered one of the most promising new antimicrobial agents to combat antibiotic resistance and have garnered significant attention over the past few decades. However, their development has been hindered…
View article: Discovery and Optimisation of Novel Bombinin-Derived Peptides from Bombina variegata against Staphylococcus aureus
Discovery and Optimisation of Novel Bombinin-Derived Peptides from Bombina variegata against Staphylococcus aureus Open
Amphibian skin-secreted antimicrobial peptides (AMPs) have garnered significant attention for their excellent biological activity and low propensity for drug resistance over the past 40 years. Bombinins and bombinin H, two classes of AMPs …
View article: Short Peptides from Asian Scorpions: Bioactive Molecules with Promising Therapeutic Potential
Short Peptides from Asian Scorpions: Bioactive Molecules with Promising Therapeutic Potential Open
Scorpion venom peptides, particularly those derived from Asian species, have garnered significant attention, offering therapeutic potential in pain management, cancer, anticoagulation, and infectious diseases. This review provides a compre…
View article: Snow Resource Reutilization: Design of Snow Collection and Compression Equipment Based on Functional Analysis Method
Snow Resource Reutilization: Design of Snow Collection and Compression Equipment Based on Functional Analysis Method Open
High-latitude regions of the Earth are rich in natural snow resources; however, owing to their negative impact on daily life, they have not been effectively utilized for a long time and are instead viewed as obstacles that require substant…
View article: Effect of furfural residue ash (FRA) as additive on Portland cement and magnesium oxysulfate cement
Effect of furfural residue ash (FRA) as additive on Portland cement and magnesium oxysulfate cement Open
The global production of furfural generates substantial amounts of furfural residue waste annually, which, if not properly managed, can lead to significant environmental pollution. However, the ash produced from the combustion of this biom…
View article: A Designed Analog of an Antimicrobial Peptide, Crabrolin, Exhibits Enhanced Anti-Proliferative and In Vivo Antimicrobial Activity
A Designed Analog of an Antimicrobial Peptide, Crabrolin, Exhibits Enhanced Anti-Proliferative and In Vivo Antimicrobial Activity Open
Antimicrobial peptides have gradually attracted interest as promising alternatives to conventional agents to control the worldwide health threats posed by antibiotic resistance and cancer. Crabrolin is a tridecapeptide extracted from the v…
View article: Distilled spirits lees ash as cement additive
Distilled spirits lees ash as cement additive Open
The voluminous generation of distilled spirits lees (DSL) in China presents a challenge for proper disposal and potential environmental pollution. In an effort to address this issue, this study aimed to find a resourceful solution for DSL …
View article: Characteristics of denitrification and microbial community in respect to various H2 pressures and distances to the gas supply end in H2-based MBfR
Characteristics of denitrification and microbial community in respect to various H2 pressures and distances to the gas supply end in H2-based MBfR Open
The hydrogen-based hollow fiber membrane biofilm reactor (H2-based MBfR) has shown to be a promising technology for nitrate (NO 3 – –N) reduction. Hollow fiber membranes (HFM) operating in a closed mode in an H 2 -based MBfR often suffer f…
View article: Evaluation of the Antimicrobial Properties of a Natural Peptide from Vespa mandarinia Venom and Its Synthetic Analogues as a Possible Route to Defeat Drug-Resistant Microbes
Evaluation of the Antimicrobial Properties of a Natural Peptide from Vespa mandarinia Venom and Its Synthetic Analogues as a Possible Route to Defeat Drug-Resistant Microbes Open
Antimicrobial peptides (AMPs) from wasp venom have a good track record and potential for drug development as tools against development of antimicrobial resistance. Herein, the biological function and activity profile of peptide VM, which w…
View article: Experimental Investigation and Model Analysis on a GaN Electrostatic Discharge Clamp
Experimental Investigation and Model Analysis on a GaN Electrostatic Discharge Clamp Open
This work carried out the experimental investigation and model analysis on a GaN electrostatic discharge (ESD) clamp, which features a discharge high electron mobility transistor (HEMT) and a voltage divider formed by a lateral field effec…
View article: Enhanced Reverse Recovery Performance in Superjunction MOSFET with Reduced Hole-Barrier
Enhanced Reverse Recovery Performance in Superjunction MOSFET with Reduced Hole-Barrier Open
High reverse recovery charge (Q RR ) and resultant high switching losses have become the main factors that constrain the performance and application area of superjunction MOSFET (SJ-MOSFET). To reduce Q RR , an SJ-MOSFET with reduced hole-…
View article: Media Exposure of Covid-19 and Mental Health
Media Exposure of Covid-19 and Mental Health Open
COVID-19's aggressive appearance has caught the whole world by surprise.With the development of science and technology, people can be easily exposed to the global pandemic situation through media exposure.However, the issue that whether ex…
View article: GaN Power Integration for High Frequency and High Efficiency Power Applications: A Review
GaN Power Integration for High Frequency and High Efficiency Power Applications: A Review Open
High frequency and high efficiency operation is one of the premier interests in the signal and energy conversion applications. The wide bandgap GaN based devices possess superior properties and have demonstrated exceeding performance than …
View article: Monolithic GaN Half-Bridge Stages With Integrated Gate Drivers for High Temperature DC-DC Buck Converters
Monolithic GaN Half-Bridge Stages With Integrated Gate Drivers for High Temperature DC-DC Buck Converters Open
This paper presents a GaN based synchronous buck DC-DC converter, which monolithically integrates gate drivers and a half-bridge power stage in a 3-μm enhancement-mode (E-mode) GaN-on-Si process. The fabricated synchronous converter with i…