Explanipedia

ADVANCING PRECISION MEDICINE IN NIGERIA: THE ROLE OF PATIENT ENGAGEMENT AND EDUCATIONAL MATERIALS IN CARE ACTIVATION—A PILOT STUDY Open

Runcie C.W. Chidebe, O Akapo, Sampson Chinonso Ipiankama, Ozioma Uzodinma, Silvia Bornengo , et al. · 2025

SELF-ESTEEM AS A BUFFER: COGNITIVE EMOTION REGULATION AND DEPRESSION AMONG NIGERIAN WOMEN WITH ADVANCED BREAST CANCER Open

Maria‐Chidi Christiana Onyedibe, Runcie C.W. Chidebe · 2025

A NATIONAL STUDY ON ACCESS TO PSYCHOLOGICAL SUPPORT AND PSYCHOTHERAPY FOR PATIENTS WITH ADVANCED BREAST CANCER IN NIGERIA Open

Runcie C.W. Chidebe, Sampson Chinonso Ipiankama, Maria‐Chidi Christiana Onyedibe, Ifeoma Okoye, Simeon Chinedu Aruah , et al. · 2025

PREGNANCY, FERTILITY TREATMENTS: INVESTIGATING ONCOFERTILITY IN FEMALE METASTATIC BREAST CANCER PATIENTS Open

Oiza Tessy Ahmadu, Ejike Ugwu, Sampson Chinonso Ipiankama, Deborah N. Ejemole, Faridah Banwo , et al. · 2025

Ensuring access to multidisciplinary care in advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 4) Open

Shani Paluch‐Shimon, Laura Biganzoli, Julie Torode, Ginny Mason, Sungbae Kim , et al. · 2025

Despite remarkable advances in the management of advanced breast cancer (ABC), profound disparities persist in outcomes and access to quality care globally. A multidisciplinary approach, where specialists collaborate on diagnosis, treatmen…

Improving equitable access to comprehensive care for people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 9) Open

Alexandru Eniu, Runcie C.W. Chidebe, Peter Vuylsteke, Mariana Chávez‐MacGregor, Frédérique Penault‐Llorca , et al. · 2025

Advanced breast cancer (ABC) remains an incurable yet treatable disease, requiring lifelong care. While treatment advancements have extended survival for many patients, access to these innovations is far from universal. There remains a cri…

Improving the quality of life of people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (goal 3) Open

Karen A. Gelmon, Cynthia Villarreal‐Garza, Dawn Aubel, Hope S. Rugo, Julia Maués , et al. · 2025

CONSORT 2025 statement: updated guideline for reporting randomized trials: a Korean translation Open

Sally Hopewell, An‐Wen Chan, Gary S. Collins, Asbjørn Hróbjartsson, David Moher , et al. · 2025

배경: 잘 설계되고 적절하게 실행된 무작위 배정 임상시험은 의료 개입의 효과에 대한 가장 신뢰할 수 있는 증거라고 할 수 있다. 그러나 연구 보고의 질이 미흡하다는 많은 증거가 있다. CONSORT(통합 임상시험 보고 기준)는 이러한 보고의 질을 개선하기 위해 고안되었으며, 무작위 임상시험 보고서가 포함해야 할 최소한의 항목을 제시한다. CONSORT는 1996년에 처음 발표된 후 2001년과 2010년에 개정되었다. 여기에…

Who Reconstitutes the Chemotherapy? The Educational and Practice Needs of Oncology Pharmacists in West Africa: A Call for Multidisciplinary Team Approach in Oncology Care Open

Runcie C.W. Chidebe, Ramatu Masud Alabelewe, Krishna Prasad Sapkota, Darlingtina Esiaka, Candidus Nwakasi , et al. · 2025

PURPOSE Oncology pharmacists (OPs) play a crucial role in cancer care, treatment, survivorship, and multidisciplinary teams (MDTs). OPs have specialized training in designing, administering, monitoring, and modifying oncology chemotherapy;…

SPIRIT 2025 statement: updated guideline for protocols of randomized trials Open

An‐Wen Chan, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F. Schulz , et al. · 2025

SPIRIT 2025 statement: Updated guideline for protocols of randomised trials Open

An‐Wen Chan, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F. Schulz , et al. · 2025

Importance The protocol of a randomised trial is the foundation for study planning, conduct, reporting, and external review. However, trial protocols vary in their completeness and often do not address key elements of design and conduct. T…

SPIRIT 2025 statement: updated guideline for protocols of randomised trials Open

An‐Wen Chan, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F. Schulz , et al. · 2025

Importance The protocol of a randomised trial is the foundation for study planning, conduct, reporting, and external review. However, trial protocols vary in their completeness and often do not address key elements of design and conduct. T…

SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials Open

Asbjørn Hróbjartsson, Isabelle Boutron, Sally Hopewell, David Moher, Kenneth F. Schulz , et al. · 2025

High quality protocols facilitate proper planning, conduct, reporting, and external review of randomised trials, yet their completeness varies and key elements are often not considered. To strengthen good reporting of trial protocols, the …

CONSORT 2025 statement: updated guideline for reporting randomised trials Open

Sally Hopewell, An‐Wen Chan, Gary S. Collins, Asbjørn Hróbjartsson, David Moher , et al. · 2025

Background Well designed and properly executed randomised trials are considered the most reliable evidence on the benefits of healthcare interventions. However, there is overwhelming evidence that the quality of reporting is not optimal. T…

CONSORT 2025 statement: updated guideline for reporting randomized trials Open

Sally Hopewell, An‐Wen Chan, Gary S. Collins, Asbjørn Hróbjartsson, David Moher , et al. · 2025

CONSORT 2025 statement: Updated guideline for reporting randomised trials Open

Sally Hopewell, An‐Wen Chan, Gary S. Collins, Asbjørn Hróbjartsson, David Moher , et al. · 2025

Background Well designed and properly executed randomised trials are considered the most reliable evidence on the benefits of healthcare interventions. However, there is overwhelming evidence that the quality of reporting is not optimal. T…

CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials Open

Sally Hopewell, An‐Wen Chan, Gary S. Collins, Asbjørn Hróbjartsson, David Moher , et al. · 2025

We dedicate CONSORT 2025 to the late Doug Altman who was instrumental in the development of the SPIRIT and CONSORT statements and whose files and correspondence contributed to this update following his death. We gratefully acknowledge the …

Using cancer survivorship experiences to inform cancer advocacy in Nigeria Open

Chinelo C. Nduka, Chizobam Nweke, Runcie C.W. Chidebe, Candidus Nwakasi · 2025

We used a qualitative descriptive approach and recruited 19 BC survivors through a purposive sampling method. The participants were engaged in four focus group discussions. Analysis of the data resulted in four main themes with direction i…

Challenges and opportunities in ovarian cancer care: A qualitative study of clinician perspectives from 24 low- and middle-income countries Open

Anmol Bajwa, Runcie C.W. Chidebe, Tracey L. Adams, Garth Funston, Isabelle Soerjomataram , et al. · 2025

This study reveals the complexity of ovarian cancer treatment and care in LMICs and the need to mitigate disparities in these regions, underscoring the need for patient-centred, context specific and intersectoral strategies to be considere…

The Global Fund, Cervical Cancer, and HPV infections: what can low- and middle-income countries do to accelerate progress by 2030? Open

Runcie C.W. Chidebe, Alile Osayi, Julie S. Torode · 2025

This study was not funded.

Age modulates, religious coping mediates: the role of attitude to self in cancer patients’ quality of life Open

Maria‐Chidi Christiana Onyedibe, Runcie C.W. Chidebe, Barbara L. Andersen, Uzoamaka F. Ugwoke, Lawrence E. Ugwu · 2025

Background Cancer significantly impacts psychological well-being and health-related quality of life (HRQoL). This is particularly evident in low and middle-income countries (LMICs) where healthcare disparities exacerbate distress. Cognitiv…

NUMERACY SKILL USE AND SKILL PROFICIENCY AMONG OLDER WORKERS IN THE UNITED STATES Open

Takashi Yamashita, Donnette Narine, Runcie C.W. Chidebe, Phyllis Cummins, Jenna W. Kramer , et al. · 2024

Recent studies linked numeracy—the ability to understand numeric information -- and a variety of economic well-being outcomes (e.g., employment, income). However, aging is generally associated with lower numeracy skills, and in turn, older…

EDUCATION, ADULT LITERACY, AND HEALTH AMONG MIDDLE-AGED AND OLDER IMMIGRANTS IN THE UNITED STATES Open

Donnette Narine, Takashi Yamashita, Runcie C.W. Chidebe, Phyllis Cummins, Jenna W. Kramer , et al. · 2024

The education-health pathway is well-documented whereby greater human capital such as educational attainment can provide health benefits over the life course. However, there is evidence of diminishing health benefits from education for imm…

“[CERVICAL CANCER], NOT AT THIS AGE…”: TREATMENT EXPERIENCES OF OLDER WOMEN WITH ADVANCED CERVICAL CANCER Open

Runcie C.W. Chidebe, Ifeoma Okoye · 2024

Background Cervical cancer (CC) is 90% preventable with the HPV vaccine against sub-types 16 and 18, yet an estimated 21 women die every day from CC, and 7,968 die annually in Nigeria. Most of the women diagnosed with CC are older women, y…

USING CANCER SURVIVORSHIP EXPERIENCES TO INFORM CANCER ADVOCACY IN NIGERIA Open

Chizobam Nweke, Chinelo C. Nduka, Runcie C.W. Chidebe, Candidus Nwakasi · 2024

Background Despite having a high cancer burden that is still rising, Nigeria, like many rapidly aging countries in sub-Saharan Africa, due to a very high burden of infectious diseases, is not paying adequate attention to non-communicable d…

SOCIAL SUPPORT, HEALTH BEHAVIORS, SELF-ESTEEM, AND SUCCESSFUL AGING IN A SUB-SAHARAN AFRICAN SAMPLE OF OLDER ADULTS Open

JohnBosco Chika Chukwuorji, Chima C. Igbokwe, Blessing Ome, Runcie C.W. Chidebe, Beatrice Chinwe Igbokwe , et al. · 2024

Previous research demonstrates that social support facilitates successful aging across all cultures. However, the factors that potentially mediate the link between social support and successful aging remain unclear. This study examined whe…

OLDER WORKERS’ DEMOGRAPHIC AND SOCIOECONOMIC CHARACTERISTICS BY DIGITAL SKILL USE PATTERNS IN THE UNITED STATES Open

Takashi Yamashita, Donnette Narine, Runcie C.W. Chidebe, Phyllis Cummins, Jenna W. Kramer , et al. · 2024

In the current technology-rich society, having sufficient skills to use information and communication technology (ICT) for problem-solving is advantageous in the labor market from a human capital perspective. However, older workers tend to…

“We don’t do any of these things because we are a death-denying culture”: Sociocultural perspectives of Black and Latinx cancer caregivers Open

Candidus Nwakasi, Darlingtina Esiaka, Chizobam Nweke, Runcie C.W. Chidebe, Wilson Villamar , et al. · 2024

Objectives Cancer is an enormous public health burden among Black and Latinx cancer survivors, and they are at risk of facing barriers to accessing cancer treatment and support in the United States. This study explored the unique challenge…

The every woman study™ low- and middle-income countries edition protocol: A multi-country observational study to assess opportunities and challenges to improving survival and quality of life for women with ovarian cancer Open

Frances Reid, Tracey L. Adams, Rafe Sadnan Adel, Carlos Eduardo Mattos Cunha Andrade, Anmol Bajwa , et al. · 2024

Background Ovarian cancer is a challenging disease to diagnose and treat effectively with five-year survival rates below 50%. Previous patient experience research in high-income countries highlighted common challenges and opportunities to …

6th and 7th International consensus guidelines for the management of advanced breast cancer (ABC guidelines 6 and 7) Open

Fátima Cardoso, Shani Paluch‐Shimon, Eva Schumacher-Wulf, Leonor Vasconcelos de Matos, Karen A. Gelmon , et al. · 2024

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