Rui Wang
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View article: Parthenolide Restores Testosterone Biosynthesis After Nanoplastic Exposure by Blocking ROS-Driven NF-κB Nuclear Translocation
Parthenolide Restores Testosterone Biosynthesis After Nanoplastic Exposure by Blocking ROS-Driven NF-κB Nuclear Translocation Open
Nanoplastics are pervasive contaminants that adversely affect male reproductive function, yet the molecular basis of polystyrene nanoplastic (PS-NP) toxicity in immature testes and effective preventive strategies remain unclear. Here, male…
View article: Enhanced pharmacokinetic and therapeutic of GSH-responsive mPEG-b-P(HPMA)-SGI1776 conjugate for osteosarcoma
Enhanced pharmacokinetic and therapeutic of GSH-responsive mPEG-b-P(HPMA)-SGI1776 conjugate for osteosarcoma Open
Introduction SGI-1776 represents the first serine/threonine kinase inhibitor to be utilized in the treatment of osteosarcoma. It is severely restricted by poor aqueous solubility, short degradation half-life and severe side effect. Methods…
View article: Sharing emissions and removals for meeting the Paris Agreement through a distributive and corrective justice lens
Sharing emissions and removals for meeting the Paris Agreement through a distributive and corrective justice lens Open
Carbon dioxide removal (CDR) is critical for achieving net-zero and net-negative CO 2 emissions that can halt and potentially reverse global warming, respectively. However, reliable CDR is still costly and comes with considerable technolog…
View article: Scheduling in Remanufacturing Systems: A Bibliometric and Systematic Review
Scheduling in Remanufacturing Systems: A Bibliometric and Systematic Review Open
Global ambitions for net-zero emissions and resource circularity are propelling industry from linear “make-use-dispose”models toward closed-loop value creation. Remanufacturing, which aims to restore end-of-life products to a “like-new” co…
View article: Glutathione-responsive PEGylated florfenicol via disulfide linkage enhances antibacterial activity, pharmacokinetics, and biosafety
Glutathione-responsive PEGylated florfenicol via disulfide linkage enhances antibacterial activity, pharmacokinetics, and biosafety Open
Developing intelligent and responsive antimicrobial materials is critically important for the sustainable advancement of livestock production. This study prepares a glutathione-responsive mPEG–SS–florfenicol conjugate using disulfide bonds…
View article: Treg cell: Critical role of regulatory T-cells in depression
Treg cell: Critical role of regulatory T-cells in depression Open
Depression is a highly prevalent disorder of the central nervous system. The neuropsychiatric symptoms of clinical depression are persistent and include fatigue, anorexia, weight loss, altered sleep patterns, hyperalgesia, melancholia, anx…
View article: Association of vitamin D and polymorphisms of its receptor with antiviral therapy in pregnant women with hepatitis B
Association of vitamin D and polymorphisms of its receptor with antiviral therapy in pregnant women with hepatitis B Open
Maternal VD levels and VDR SNPs may be associated with the efficacy of antiviral therapy in pregnant women with high HBV viral loads. Future studies to evaluate the therapeutic value of VD and its analogs in reducing the MTCT of HBV may be…
View article: New parameter adjustment with spinal cord stimulation for postherpetic neuralgia treatment: A case report and literature review
New parameter adjustment with spinal cord stimulation for postherpetic neuralgia treatment: A case report and literature review Open
Posterpetic neuralgia (PHN), a common and often severe painful condition, is a kind of refractory neuropathic pain (NP). Although the clinical treatment of PHN including pregabalin, nerve block and pulsed radiofrequency have been devoted w…
View article: Incidence of piperacillin-specific drug antibody in patients with and without piperacillin
Incidence of piperacillin-specific drug antibody in patients with and without piperacillin Open
The aim of this study was to investigate the incidence of piperacillin-specific drug antibody in patients with and without piperacillin. Piperacillin antibody was detected by piperacillin-induced hemolysis test kit. Three hundred samples w…