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View article: The mediation effect of HDL-C: Non-HDL-C on the association between inflammatory score and recurrent coronary events
The mediation effect of HDL-C: Non-HDL-C on the association between inflammatory score and recurrent coronary events Open
Inflammatory score was associated with recurrent coronary events mediated by HDL-C: non-HDL-C ratio in diabetic CHD patients, indicating that lipoproteins might aggravate the inflammatory effect on atherosclerosis under hyperglycemia. Our …
View article: Effects of high-intensity interval training, moderate-intensity continuous training, and guideline-based physical activity on cardiovascular metabolic markers, cognitive and motor function in elderly sedentary patients with type 2 diabetes (HIIT-DM): a protocol for a randomized controlled trial
Effects of high-intensity interval training, moderate-intensity continuous training, and guideline-based physical activity on cardiovascular metabolic markers, cognitive and motor function in elderly sedentary patients with type 2 diabetes (HIIT-DM): a protocol for a randomized controlled trial Open
Background and objective Sedentary behavior is of increasing concern in older patients with type 2 diabetes mellitus (T2DM) due to its potential adverse effects on cardiovascular health, cognitive function, and motor function. While regula…
View article: Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study
Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study Open
Background The previous study investigated whether the functions of small, medium, and large high density lipoprotein (S/M/L-HDL) are correlated with protein changes in mice. Herein, the proteomic and functional analyses of high density li…
View article: Additional file 1 of Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study
Additional file 1 of Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study Open
Additional file 1: Table S1.Mouse HDL particle proteins identified previously in two or more studies. Table S2. Acquired mouse and rat HDL proteomic studies information (2005-2021). Table S3. Human HDL proteins identified previously in thr…
View article: Additional file 2 of Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study
Additional file 2 of Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study Open
Additional file 2: Table S5. The MS data of L/M/S-HDL subclasses from healthy males (n=6). Table S6.The MS data of L/M/S-HDL subclasses from rats (n=3).
View article: Efficacy and Safety of High-Density Lipoprotein/Apolipoprotein A1 Replacement Therapy in Humans and Mice With Atherosclerosis: A Systematic Review and Meta-Analysis
Efficacy and Safety of High-Density Lipoprotein/Apolipoprotein A1 Replacement Therapy in Humans and Mice With Atherosclerosis: A Systematic Review and Meta-Analysis Open
Background: Although elevation of HDL-C levels by pharmaceutical drugs have no benefit of cardiovascular endpoint, the effect of high-density lipoprotein/apolipoprotein A1 (HDL/apoA-1) replacement therapy on atherosclerosis is controversia…
View article: Heart Rate Fluctuation and Mortality in Critically Ill Myocardial Infarction Patients: A Retrospective Cohort Study
Heart Rate Fluctuation and Mortality in Critically Ill Myocardial Infarction Patients: A Retrospective Cohort Study Open
Background: Whether heart rate (HR) fluctuation after admission has an impact on the outcomes of critically ill myocardial infarction (MI) patients in intensive care unit remains unknown. Methods: A total of 2,031 MI patients were enrolled…
View article: Central Venous Pressure and Acute Kidney Injury in Critically Ill Patients with Multiple Comorbidities: A Large Retrospective Cohort Study
Central Venous Pressure and Acute Kidney Injury in Critically Ill Patients with Multiple Comorbidities: A Large Retrospective Cohort Study Open
Background: Given the traditional acceptance of higher central venous pressure (CVP) levels, clinicians ignore the incidence of acute kidney injury (AKI). The objective of this study is to assess whether elevated CVP is associated with inc…
View article: Large HDL2 combined with inflammatory factors as superior predictors for coronary artery disease than small HDL3
Large HDL2 combined with inflammatory factors as superior predictors for coronary artery disease than small HDL3 Open
Large HDL2 is superior to small HDL3 in the inverse association with CAD. The combination of HDL2, MCP-1, and hsCRP with CRFs provides an optimal prediction for CAD.
View article: Association of renal cyst and type A acute aortic dissection with hypertension
Association of renal cyst and type A acute aortic dissection with hypertension Open
Renal cyst status correlates with the risk of TA-AAD with hypertension in middle-aged and elderly patients, and exhibits different degrees of vascular lesion in aortic dissection. We therefore suggest that different antihypertensive standa…
View article: Development and validation of a prognostic nomogram for myocardial infarction patients in intensive care units: a retrospective cohort study
Development and validation of a prognostic nomogram for myocardial infarction patients in intensive care units: a retrospective cohort study Open
Objectives We aimed to develop and validate a prognostic nomogram and evaluate the discrimination of the nomogram model in order to improve the prediction of 30-day survival of critically ill myocardial infarction (MI) patients. Design A r…
View article: Association between HDL-C levels and menopause: a meta-analysis
Association between HDL-C levels and menopause: a meta-analysis Open
Purpose Menopause modifies women’s lipid profiles. However, the fact that it is still unclear whether high-density lipoprotein-cholesterol (HDL-C) levels decrease in postmenopausal women necessitated a systematic review and meta-analysis. …
View article: Plasma high-density lipoprotein cholesterol responses to endurance exercise training: A meta-analysis of randomized controlled trials
Plasma high-density lipoprotein cholesterol responses to endurance exercise training: A meta-analysis of randomized controlled trials Open
Background: Endurance exercise improves lipid and lipoproteins levels, while low high-density lipoprotein cholesterol (HDL-C) levels are risk factors for cardiovascular disease. There is a lack of evidence for the exercise characteristics …