Runqiang Chen
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View article: Antibody-based binding domain fused to TCRγ chain facilitates T cell cytotoxicity for potent anti-tumor response
Antibody-based binding domain fused to TCRγ chain facilitates T cell cytotoxicity for potent anti-tumor response Open
View article: Supplementary Figure 5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 286K
View article: Data from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Data from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
Epithelial–mesenchymal transition (EMT) plays a crucial role in the development of cancer metastasis. The mitogen-activated protein (MAP) kinases extracellular signal–regulated kinase, c-jun-NH2-kinase, and p38 have been …
View article: Supplementary Figure Legends 1-5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure Legends 1-5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 66K
View article: Supplementary Figure 2 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 2 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 240K
View article: Supplementary Figure 4 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 4 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 146K
View article: Supplementary Figure 5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 286K
View article: Supplementary Figure 3 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 3 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 234K
View article: Data from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Data from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
Epithelial–mesenchymal transition (EMT) plays a crucial role in the development of cancer metastasis. The mitogen-activated protein (MAP) kinases extracellular signal–regulated kinase, c-jun-NH2-kinase, and p38 have been …
View article: Supplementary Figure 1 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 1 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 226K
View article: Supplementary Figure Legends 1-5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure Legends 1-5 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 66K
View article: Supplementary Figure 3 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 3 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 234K
View article: Supplementary Figure 1 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 1 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 226K
View article: Supplementary Figure 4 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 4 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 146K
View article: Supplementary Figure 2 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway
Supplementary Figure 2 from BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3β Signaling Pathway Open
PDF file - 240K
View article: Antibody-based binding domain fused to TCRγ chain facilitates T cell cytotoxicity for potent anti-tumor response
Antibody-based binding domain fused to TCRγ chain facilitates T cell cytotoxicity for potent anti-tumor response Open
Supplementary table and figures
View article: Chimeric mRNA-based COVID-19 vaccine induces protective immunity against Omicron and Delta variants
Chimeric mRNA-based COVID-19 vaccine induces protective immunity against Omicron and Delta variants Open
View article: Delivering an mRNA vaccine using a lymphatic drug delivery device improves humoral and cellular immunity against SARS-CoV-2
Delivering an mRNA vaccine using a lymphatic drug delivery device improves humoral and cellular immunity against SARS-CoV-2 Open
The exploration and identification of safe and effective vaccines for the SARS-CoV-2 pandemic have captured the world's attention and remains an ongoing issue due to concerns of balancing protection against emerging variants of concern whi…
View article: A novel single TCR gamma chain fused with antibody-based binding domain facilitates T cell cytotoxicity for potent anti-tumor response without forming TCR-CD3 complex
A novel single TCR gamma chain fused with antibody-based binding domain facilitates T cell cytotoxicity for potent anti-tumor response without forming TCR-CD3 complex Open
Chimeric antigen receptor (CAR)-T cells have shown potent clinical efficacy in the treatment of hematopoietic malignancies. However, much less has been achieved in solid tumors, in part due to the CAR-T cell exhaustion caused by inhibitory…
View article: Chimeric mRNA based COVID-19 vaccine induces protective immunity against Omicron and Delta
Chimeric mRNA based COVID-19 vaccine induces protective immunity against Omicron and Delta Open
The emerging SARS-CoV-2 variants of concern (VOCs) exhibit enhanced transmission and immune escape, reducing the efficacy and effectiveness of the two FDA-approved mRNA vaccines. Here, we explored various strategies to develop novel mRNAs …
View article: Directing an mRNA-LNP vaccine toward lymph nodes improves humoral and cellular immunity against SARS-CoV-2
Directing an mRNA-LNP vaccine toward lymph nodes improves humoral and cellular immunity against SARS-CoV-2 Open
The exploration and identification of safe and effective vaccines for the SARS-CoV-2 pandemic has captured the world’s attention and remains an ongoing issue in order to protect against emerging variants of concern (VoCs) while generating …
View article: Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny
Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny Open
Individual naive CD8 T cells activated in lymphoid organs differentiate into functionally diverse and anatomically distributed T cell phylogenies in response to intracellular microbes. During infections that resolve rapidly, including live…
View article: RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing
RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing Open
View article: Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation Open
View article: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation Open
View article: Atmospheric Environment Five Dimensional Representation Model
Atmospheric Environment Five Dimensional Representation Model Open
Modern simulation applications need physically consistent atmospheric environment representation. The consistency, standardized and effective atmospheric environment data representation are critical for simulation applications, it is the b…