Rui Jiang
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View article: hECA v2.0: an AI-ready ensemble cell atlas of single-cell RNA and ATAC sequencing data
hECA v2.0: an AI-ready ensemble cell atlas of single-cell RNA and ATAC sequencing data Open
With the growing accumulation of scattered single-cell data and the rapid advancement of artificial intelligence (AI), there is a pressing need for a high-quality, well-organized, and AI-ready single-cell data resources to support large-sc…
View article: Comparative Study of the Fatty Acid and Phenolic Profiles of Tender and Mature Coconut for Coconut Milk Production
Comparative Study of the Fatty Acid and Phenolic Profiles of Tender and Mature Coconut for Coconut Milk Production Open
Coconut milk is a widely consumed plant-based milk alternative, valued for its creamy texture and functional properties. This study systematically evaluated the fatty acid and phenolic profiles of coconut meat and water at tender and matur…
View article: Human-scATAC-Corpus: a comprehensive database of scATAC-seq data
Human-scATAC-Corpus: a comprehensive database of scATAC-seq data Open
Single-cell assay for transposase-accessible chromatin using sequencing (scATAC-seq) profiles chromatin accessibility at cellular resolution, making it possible to reveal epigenomic landscapes that govern gene regulation in a variety of ce…
View article: Synthesis of Linear Modified Siloxane-Based Thickeners and Study of Their Phase Behavior and Thickening Mechanism in Supercritical Carbon Dioxide
Synthesis of Linear Modified Siloxane-Based Thickeners and Study of Their Phase Behavior and Thickening Mechanism in Supercritical Carbon Dioxide Open
To address critical limitations of ultra-low viscosity supercritical CO2 fracturing fluids, including excessive fluid loss and inadequate proppant transport capacity, a series of thickeners designed to significantly enhance CO2 viscosity w…
View article: Computed tomography features of recurrent acute pancreatitis based on different etiologies
Computed tomography features of recurrent acute pancreatitis based on different etiologies Open
RAP presents with distinct clinical and CT features depending on its etiology. Hypertriglyceridemic RAP is associated with milder disease severity than biliary RAP. Our findings provide new insights into the etiology-specific manifestation…
View article: Human-scATAC-Corpus: a comprehensive database of scATAC-seq data
Human-scATAC-Corpus: a comprehensive database of scATAC-seq data Open
Single-cell Assay for Transposase-Accessible Chromatin using sequencing (scATAC-seq) profiles chromatin accessibility at cellular resolution, making it possible to reveal epigenomic landscapes that govern gene regulation in a variety of ce…
View article: Research progress of thickener for supercritical carbon dioxide fracturing fluid
Research progress of thickener for supercritical carbon dioxide fracturing fluid Open
Compared to traditional water-based fracturing fluids, which often result in reservoir fracturing damages, water consumption, and incomplete flowback, supercritical carbon dioxide (scCO2) fracturing technology has gained attention from sch…
View article: Speech brain–computer interfaces for communication rehabilitation: State‐of‐the‐art decoding models, clinical applications, and ethical challenges
Speech brain–computer interfaces for communication rehabilitation: State‐of‐the‐art decoding models, clinical applications, and ethical challenges Open
Speech brain–computer interfaces (BCIs) represent an interdisciplinary neural engineering innovation enabling communication rehabilitation for individuals with anarthria or severe dysarthria. By decoding cortical activity into text or synt…
View article: Hi-Cformer enables multi-scale chromatin contact map modeling for single-cell Hi-C data analysis
Hi-Cformer enables multi-scale chromatin contact map modeling for single-cell Hi-C data analysis Open
Single-cell Hi-C captures the three-dimensional organization of chromatin in individual cells and provides insights into fundamental genomic processes such as gene regulation and transcription. While analyses of bulk Hi-C data have reveale…
View article: Integration of single-cell and spatial transcriptomics by SEU-TCA reveals the spatial origin of early cardiac progenitors
Integration of single-cell and spatial transcriptomics by SEU-TCA reveals the spatial origin of early cardiac progenitors Open
Obtaining single-cell spatial information remains a challenge in spatial transcriptomics. Here we develop SEU-TCA, a method that leverages transfer component analysis to improve single-cell spatial mapping accuracy. Application to multiple…
View article: Threat Intelligence Named Entity Recognition Based on Segment-Level Information Extraction and Similar Semantic Space Construction
Threat Intelligence Named Entity Recognition Based on Segment-Level Information Extraction and Similar Semantic Space Construction Open
Threat intelligence is crucial for the early detection of network security threats, and named entity recognition (NER) plays a critical role in this process. However, traditional NER models based on sequence tagging primarily focus on word…
View article: Sustainable Synthesis of Concentrated Formate via CO<sub>2</sub> Electrolysis Integrated with Cl<sub>2</sub> Formation
Sustainable Synthesis of Concentrated Formate via CO<sub>2</sub> Electrolysis Integrated with Cl<sub>2</sub> Formation Open
Integrating CO 2 electrolysis with an industrially relevant anodic reaction enhances the economic feasibility and reduces carbon emissions in practical operations. In this study, we present an electrosynthesis strategy that integrates the …
View article: Sustainable Synthesis of Concentrated Formate via CO<sub>2</sub> Electrolysis Integrated with Cl<sub>2</sub> Formation
Sustainable Synthesis of Concentrated Formate via CO<sub>2</sub> Electrolysis Integrated with Cl<sub>2</sub> Formation Open
Integrating CO 2 electrolysis with an industrially relevant anodic reaction enhances the economic feasibility and reduces carbon emissions in practical operations. In this study, we present an electrosynthesis strategy that integrates the …
View article: An Improved Self-Organizing Map (SOM) Based on Virtual Winning Neurons
An Improved Self-Organizing Map (SOM) Based on Virtual Winning Neurons Open
Self-Organizing Map (SOM) neural networks can project complex, high-dimensional data onto a two-dimensional plane for data visualization, enabling an intuitive understanding of the distribution and symmetric structures of such data, thereb…
View article: Facilitators and barriers to chronic non-communicable disease management under family doctor contracting services in China
Facilitators and barriers to chronic non-communicable disease management under family doctor contracting services in China Open
Background Chronic non-communicable diseases (NCDs) pose a significant health burden in China exacerbated by population aging and rapid urbanization. The Family Doctor Contracting Service has been implemented in China as a primary health c…
View article: SimdMSM: SIMD-accelerated Multi-Scalar Multiplication Framework for zkSNARKs
SimdMSM: SIMD-accelerated Multi-Scalar Multiplication Framework for zkSNARKs Open
Multi-scalar multiplication (MSM) is the primary building block in many pairing-based zero-knowledge proof (ZKP) systems. MSM at large scales has become the main bottleneck in ZKP implementations. Inspired by existing SIMD-accelerated work…
View article: Benchmarking Multimodal RAG through a Chart-based Document Question-Answering Generation Framework
Benchmarking Multimodal RAG through a Chart-based Document Question-Answering Generation Framework Open
Multimodal Retrieval-Augmented Generation (MRAG) enhances reasoning capabilities by integrating external knowledge. However, existing benchmarks primarily focus on simple image-text interactions, overlooking complex visual formats like cha…
View article: INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation
INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation Open
Recent advances in spatial epigenomic techniques have given rise to spatial assay for transposase-accessible chromatin using sequencing (spATAC-seq) data, enabling the characterization of epigenomic heterogeneity and spatial information si…
View article: EpiAgent: Foundation Model for Single-Cell Epigenomics
EpiAgent: Foundation Model for Single-Cell Epigenomics Open
Large-scale foundation models have recently opened a new avenue to artificial general intelligence for life sciences, showing great promise in the analysis of single-cell transcriptomic data. Nevertheless, such challenges as the tremendous…
View article: Effects of Stand Structural Characteristics, Diversity, and Stability on Carbon Storage Across Different Densities in Natural Forests: A Case Study in the Xiaolong Mountains, China
Effects of Stand Structural Characteristics, Diversity, and Stability on Carbon Storage Across Different Densities in Natural Forests: A Case Study in the Xiaolong Mountains, China Open
The carbon storage in forest ecosystems is closely linked to biomass, and its dynamic changes are of significant importance for assessing forest structure and function, as well as their response to global climate change. Recently, the rese…
View article: Association between coffee consumption and life expectancy: a prospective cohort study from NHANES 2001–2018
Association between coffee consumption and life expectancy: a prospective cohort study from NHANES 2001–2018 Open
Objective: To assess the association between coffee consumption and life expectancy among the US adults. Design: Prospective cohort. Setting: National representative survey in the United States, 2001–2018. Participants: A total of 43 114 p…