Explanipedia

Synthesis and functional analysis of polysaccharide-Fe (III) complexes from Lilium davidii var. willmottiae: a step toward bioavailable iron supplements Open

Hong-Bo Jiang, Xiaojun Li, Ren-Di Jiang, Yinquan Wang, Fankui Zeng · 2025

Characterization of a SARS-CoV-2 infection model in golden hamsters with diabetes mellitus Open

Haofeng Lin, Ren-Di Jiang, Renyi Qin, Bing Yao, Wentao Zeng , et al. · 2025

Being widespread across the globe, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) keeps evolving and generating new variants and continuously poses threat to public health, especially to the population with chronic comorbidit…

ASurvey: Spatiotemporal Consistency in Video Generation Open

Z X Yin, Kehai Chen, Xuefeng Bai, Ren-Di Jiang, Juntao Li , et al. · 2025

Video generation, by leveraging a dynamic visual generation method, pushes the boundaries of Artificial Intelligence Generated Content (AIGC). Video generation presents unique challenges beyond static image generation, requiring both high-…

Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster Open

Ren-Di Jiang, Yang Luo, Hao-Feng Lin, Xiao-Shuang Zheng, Wentao Zeng , et al. · 2025

Establishment of a human organoid-based evaluation system for assessing interspecies infection risk of animal-borne coronaviruses Open

Qian-Chun Gong, Ren-Di Jiang, Lina Ji, Haofeng Lin, Meiqin Liu , et al. · 2024

The COVID-19 pandemic presents a major threat to global public health. Several lines of evidence have shown that the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), along with two other highly pathogenic coronaviruses, SARS-C…

Characterization of the SARS-CoV-2 BA.5 Variants in H11-K18-hACE2 Hamsters Open

Mei Dong, Haofeng Lin, Margaret Pan, Minghong Huang, Meiqin Liu , et al. · 2024

This study aims to comprehensively characterize the SARS-CoV-2 BA.5 variants using K18 hACE2 transgenic mice and golden hamsters as model organisms. Previous research on SARS-CoV-2 has utilized both mouse and hamster models, leading to con…

Characterization of the SARS-CoV-2 BA.5 Variants in H11-K18-hACE2 Hamsters Open

Mei Dong, Haofeng Lin, Margaret Pan, Minghong Huang, Meiqin Liu , et al. · 2024

A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry Open

Jing Chen, Xing‐Lou Yang, Hao-Rui Si, Qian-Chun Gong, Tengcheng Que , et al. · 2023

Ecological study of cave nectar bats reveals low risk of direct transmission of bat viruses to humans Open

Kai Zhao, Wei Zhang, Bei Li, Shi-Zhe Xie, Fan Yi , et al. · 2022

Ecological study of cave nectar bats reveals low risk of direct transmission of bat viruses to humans Open

Kai Zhao, Wei Zhang, Bei Li, Shi-Zhe Xie, Yi Fan , et al. · 2022

Bats are reservoirs of various viruses. The widely distributed cave nectar bat ( Eonycteris spelaea) is known to carry both filoviruses and coronaviruses. However, the potential transmission of theses bat viruses to humans is not fu…

Antibody-Dependent Enhancement of SARS-CoV-2 Infection of Human Immune Cells: In Vitro Assessment Provides Insight in COVID-19 Pathogenesis Open

Xu-Rui Shen, Qian Li, Huiling Li, Xi Wang, Qi Wang , et al. · 2021

Patients with COVID-19 generally raise antibodies against SARS-CoV-2 following infection, and the antibody level is positively correlated to the severity of disease. Whether the viral antibodies exacerbate COVID-19 through antibody-depende…

Identification of potent human neutralizing antibodies against SARS-CoV-2 implications for development of therapeutics and prophylactics Open

Shaojuan Zhao, Huajun Zhang, Xing‐Lou Yang, Haiwei Zhang, Ying Chen , et al. · 2021

Genetic Mutation of SARS-CoV-2 during Consecutive Passages in Permissive Cells Open

Ying Chen, Meiqin Liu, Yun Luo, Ren-Di Jiang, Hao-Rui Si , et al. · 2021

Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates Open

Yan-Feng Yao, Ze-Jun Wang, Ren-Di Jiang, Xue Hu, Huajun Zhang , et al. · 2021

Stability of SARS-CoV-2 on the Surfaces of Three Meats in the Setting That Simulates the Cold Chain Transportation Open

Xiao-Li Feng, Bei Li, Hao-Feng Lin, Hong-Yi Zheng, Ren-Rong Tian , et al. · 2021

Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin Open

Peng Zhou, Xing‐Lou Yang, Xian-Guang Wang, Ben Hu, Lei Zhang , et al. · 2020

An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques Open

Liqiang Feng, Qian Wang, Chao Shan, Chenchen Yang, Ying Feng , et al. · 2020

Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques Open

Chao Shan, Yanfeng Yao, Xing‐Lou Yang, Yiwu Zhou, Ge Gao , et al. · 2020

Bat mammalian orthoreoviruses cause severe pneumonia in mice Open

Ren-Di Jiang, Bei Li, Xiangling Liu, Meiqin Liu, Jing Chen , et al. · 2020

Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2 Open

Ren-Di Jiang, Mei-Qin Liu, Ying Chen, Chao Shan, Yi-Wu Zhou , et al. · 2020

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors Open

Zhenming Jin, Xiaoyu Du, Yechun Xu, Yong‐Qiang Deng, Meiqin Liu , et al. · 2020

Infection with Novel Coronavirus (SARS-CoV-2) Causes Pneumonia in the Rhesus Macaques Open

Chao Shan, Yanfeng Yao, Xing‐Lou Yang, Yiwu Zhou, Jia Wu , et al. · 2020

Coronavirus infections are common in humans and other mammals.Coronaviruses belong to the family Coronaviridae and possess a single strand, positive-sense RNA genome ranging from 26 to 32 kilobases in length.In December, 2019, a cluster of…

A pneumonia outbreak associated with a new coronavirus of probable bat origin Open

Peng Zhou, Xing‐Lou Yang, Xian-Guang Wang, Ben Hu, Lei Zhang , et al. · 2020

Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats 1–4 . Previous studies have shown that some b…

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin Open

Peng Zhou, Xing‐Lou Yang, Xian-Guang Wang, Ben Hu, Lei Zhang , et al. · 2020

Since the SARS outbreak 18 years ago, a large number of severe acute respiratory syndrome related coronaviruses (SARSr-CoV) have been discovered in their natural reservoir host, bats. Previous studies indicated that some of those bat SARSr…

Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2 Open

Ren-Di Jiang, Meiqin Liu, Ying Chen, Chao Shan, Yiwu Zhou , et al. · 2020

COVID-19 has spread worldwide since 2019 and is now a severe threat to public health. We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV-2) that uses human angiotensinconverting enzyme 2 (hACE2) as t…

Author Correction: Characterization of a filovirus (Měnglà virus) from Rousettus bats in China Open

Xing‐Lou Yang, Chee Wah Tan, Danielle E. Anderson, Ren-Di Jiang, Bei Li , et al. · 2019

Novel hepacivirus in Asian house shrew, China Open

Hua Guo, Chunlin Cai, Bo Wang, Fei Zhuo, Ren-Di Jiang , et al. · 2019

Longitudinal Surveillance of Betacoronaviruses in Fruit Bats in Yunnan Province, China During 2009–2016 Open

Yun Luo, Bei Li, Ren-Di Jiang, Bingjie Hu, Dongsheng Luo , et al. · 2018

Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015 Open

Xing‐Lou Yang, Yunzhi Zhang, Ren-Di Jiang, Hua Guo, Wei Zhang , et al. · 2017

Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%-99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism. Co-infection with …

Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015 Open

Xing‐Lou Yang, Yunzhi Zhang, Ren-Di Jiang, Hua Guo, Wei Zhang , et al. · 2017

Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%–99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism. Co-infection with …

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