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View article: Layer-by-Layer Multitargeting Strategy for Enhanced Photothermal Therapy
Layer-by-Layer Multitargeting Strategy for Enhanced Photothermal Therapy Open
Photothermal therapy (PTT) presents unique advantages, including high temporal and spatial controllability and relatively few toxic side effects. Active targeting modifications of photothermal agents can deliver nanoprobes to tumors more e…
View article: Identifying Dietary Triggers Among Individuals with Overweight and Obesity: An Ecological Momentary Assessment Study
Identifying Dietary Triggers Among Individuals with Overweight and Obesity: An Ecological Momentary Assessment Study Open
Background/Objectives: Excess adiposity, affecting 43% of the global adult population, is a major contributor to cardiometabolic diseases. Lifestyle behaviours, specifically dietary habits, play a key role in weight management. Real-time a…
View article: Quasi-Distribution Appraisal Based on Piecewise Bézier Curves: An Objective Evaluation Method about Finite Element Analysis
Quasi-Distribution Appraisal Based on Piecewise Bézier Curves: An Objective Evaluation Method about Finite Element Analysis Open
A class of quasi-distribution evaluation criteria based on piecewise Bezier curves is proposed to address the issue of the inability to objectively evaluate finite element models. During the optimization design of mechanical parts, finite …
View article: Development and validation of the Dermatology Social Comparison (DSC) Scale
Development and validation of the Dermatology Social Comparison (DSC) Scale Open
Background Social comparison, the process of evaluating one's characteristics in relation to others, influences individuals' self‐perception and behavior. However, instruments are scarce for assessing social comparison in the medical setti…
View article: Activin receptors in human cancer: Functions, mechanisms, and potential clinical applications
Activin receptors in human cancer: Functions, mechanisms, and potential clinical applications Open
Activins are members of the transforming growth factor-β (TGF-β) superfamily and act as key regulators in various physiological processes, such as follicle and embryonic development, as well as in multiple human diseases, including cancer.…
View article: Preconception maternal retinal venular widening and steeper resistance increments in the utero-fetoplacental circulation in pregnancy
Preconception maternal retinal venular widening and steeper resistance increments in the utero-fetoplacental circulation in pregnancy Open
We investigated the relationship of preconception maternal retinal vasculature and utero-fetoplacental circulation in ensuing pregnancy. Embedded in a hospital-based, prospective preconception cohort, 396 women with a singleton live birth …
View article: Manganese-Based Nanotheranostics for Magnetic Resonance Imaging-Mediated Precise Cancer Management
Manganese-Based Nanotheranostics for Magnetic Resonance Imaging-Mediated Precise Cancer Management Open
Manganese (Mn)-based magnetic resonance imaging (MRI) has become a competitive imaging modality for cancer diagnosis due to its advantages of non-invasiveness, high resolution and excellent biocompatibility. In recent years, a variety of M…
View article: Preconception maternal retinal arteriolar narrowing and fetal growth throughout pregnancy: A prospective cohort study
Preconception maternal retinal arteriolar narrowing and fetal growth throughout pregnancy: A prospective cohort study Open
Objective To investigate the association between preconception maternal retinal arteriolar calibre and fetal growth. Design, setting and population A hospital‐based, prospective preconception cohort including 369 women with a singleton liv…
View article: Early Pregnancy Maternal Plasma Phospholipid Saturated Fatty Acids and Fetal Growth: Findings from a Multi-Racial/Ethnic Birth Cohort in US
Early Pregnancy Maternal Plasma Phospholipid Saturated Fatty Acids and Fetal Growth: Findings from a Multi-Racial/Ethnic Birth Cohort in US Open
Saturated fatty acids (SFAs) during pregnancy are associated with disrupted metabolic programming among offspring at birth and later growth. We examined plasma phospholipid SFAs in early pregnancy and fetal growth throughout pregnancy. We …
View article: Understanding Discordant Perceptions of Disease Severity Between Physicians and Patients With Eczema and Psoriasis Using Structural Equation Modeling
Understanding Discordant Perceptions of Disease Severity Between Physicians and Patients With Eczema and Psoriasis Using Structural Equation Modeling Open
Importance Patients and physicians often have differing opinions on the patient’s disease severity. This phenomenon, termed discordant severity grading ( DSG ), hinders the patient-physician relationship and is a source of frustration. Obj…
View article: <scp>miR</scp>‐31 ameliorates type 2 diabetic vascular damage through up‐regulation of hypoxia‐inducible factor‐1α/vascular endothelial growth <scp>factor‐A</scp>
<span>miR</span>‐31 ameliorates type 2 diabetic vascular damage through up‐regulation of hypoxia‐inducible factor‐1α/vascular endothelial growth <span>factor‐A</span> Open
Aims microRNA may be a new therapeutic direction for diabetes. As a typical tumor marker, miR‐31 is involved in a variety of metabolic diseases, but the specific role is still unclear. This study aimed to investigate the effect of miR‐31 o…
View article: Optimal first trimester HbA1c threshold to identify Singaporean women at risk of gestational diabetes mellitus and adverse pregnancy outcomes: A pilot study
Optimal first trimester HbA1c threshold to identify Singaporean women at risk of gestational diabetes mellitus and adverse pregnancy outcomes: A pilot study Open
This pilot study examined the use of early HbA1c in screening for gestational diabetes mellitus and adverse pregnancy outcomes in Singapore. One hundred and fifty-one pregnant women with a gestational age of under 14 weeks had an HbA1c tes…
View article: Gender-Specific Reference Charts of Fetal Head Circumference in a Singaporean Population
Gender-Specific Reference Charts of Fetal Head Circumference in a Singaporean Population Open
Introduction: With the global outbreak of Zika virus and its association with microcephaly, an up-to-date fetal head circumference (HC) nomogram is crucial to offer a reference standard in order to make an accurate diagnosis. This study wa…