Ruonan Duan
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View article: Trends in meat consumption and its association with menarche timing: findings from CHNS 1997–2015
Trends in meat consumption and its association with menarche timing: findings from CHNS 1997–2015 Open
View article: Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion
Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion Open
Acute ischemic stroke (AIS) triggers immune responses and neuroinflammation, contributing to brain injury. Histone lactylation, a metabolic stress-related histone modification, plays a critical role in various diseases, but its involvement…
View article: Methylglyoxal suppresses microglia inflammatory response through NRF2-IκBζ pathway
Methylglyoxal suppresses microglia inflammatory response through NRF2-IκBζ pathway Open
Methylglyoxal (MGO) is a highly reactive metabolite generated by glycolysis. Although abnormal accumulation of MGO has been reported in several autoimmune diseases such as multiple sclerosis and rheumatoid arthritis, the role of MGO in aut…
View article: 3-N-Butylphthalide Attenuates the Neuroinflammation in Rotenone-Induced Parkinson’s Disease Models via the cGas/STING Pathway
3-N-Butylphthalide Attenuates the Neuroinflammation in Rotenone-Induced Parkinson’s Disease Models via the cGas/STING Pathway Open
Abstrat Neuroinflammation plays an important role in Parkinson’s disease(PD) and contribute to the onset and progression of degeneration of dopaminergic neurons.NBP is a widly used durg in the treatment of cerebrovascular disease,and recen…
View article: Development of the Chinese preschooler dietary index: a tool to assess overall diet quality
Development of the Chinese preschooler dietary index: a tool to assess overall diet quality Open
Background Diet quality in early childhood has a long-term impact on health outcomes. However, there are scarce dietary indexes for Chinese preschool children, and the existing indexes had limited validity and reliability. This study thus …
View article: Growth Differentiation Factor 15 Protects SH-SY5Y Cells From Rotenone-Induced Toxicity by Suppressing Mitochondrial Apoptosis
Growth Differentiation Factor 15 Protects SH-SY5Y Cells From Rotenone-Induced Toxicity by Suppressing Mitochondrial Apoptosis Open
Objective Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Mitochondrial dysfunction is suspected as one of the pathogenic mechanisms of PD. Growth/differentiation Factor-15 (GDF15) has been reported…
View article: Comparison of the Diet Photograph Record to Weighed Dietary Record and 24 h Dietary Recall for Estimating Energy and Nutrient Intakes Among Chinese Preschoolers
Comparison of the Diet Photograph Record to Weighed Dietary Record and 24 h Dietary Recall for Estimating Energy and Nutrient Intakes Among Chinese Preschoolers Open
This study aimed to assess the relative validity of the diet photograph record (DP) for measuring the energy and nutrient intakes against the weighed dietary record (WD) and the 24 h dietary recall (HR) in the Chinese preschoolers. In this…
View article: The Chinese Adolescent Cohort Study: Design, Implementation, and Major Findings
The Chinese Adolescent Cohort Study: Design, Implementation, and Major Findings Open
The importance of diet quality on children's growth is being increasingly recognized. The Chinese Adolescent Cohort (CAC) is a longitudinal cohort study to comprehensively investigate the health impacts of nutritional factors on child grow…
View article: Beyond protein intake: does dietary fat intake in the year preceding pregnancy and during pregnancy have an impact on gestational diabetes mellitus?
Beyond protein intake: does dietary fat intake in the year preceding pregnancy and during pregnancy have an impact on gestational diabetes mellitus? Open
Purpose Studies regarding the association between dietary fat intake and gestational diabetes mellitus (GDM) are limited and provide conflicting findings. Thus, the study aims to examine the association of dietary fat intake in the year pr…
View article: The overall diet quality in childhood is prospectively associated with the timing of puberty
The overall diet quality in childhood is prospectively associated with the timing of puberty Open
Purpose The influences of nutrition in childhood on puberty onset could have sustained consequences for health and wellbeing later in life. The aim of this study was to investigate the prospective association of diet quality prior to puber…
View article: Modern dietary pattern is prospectively associated with earlier age at menarche: data from the CHNS 1997–2015
Modern dietary pattern is prospectively associated with earlier age at menarche: data from the CHNS 1997–2015 Open
Background Early age at menarche is associated with risk of several chronic diseases. Prospective study on the association between dietary pattern and timing of menarche is sparse. We examined whether dietary patterns prior to the menarche…
View article: The Nutrition and Health in Southwest China (NHSC) study: design, implementation, and major findings
The Nutrition and Health in Southwest China (NHSC) study: design, implementation, and major findings Open
Background There are few studies of nutritional and genetic factors and their interactions on the risk of noncommunicable diseases (NCDs) among Chinese adults. Objective Our aim for the Nutrition and Health in Southwest China (NHSC) study …
View article: Nutrition in Pregnancy and Growth in Southwest China (NPGSC) cohort: Design, implementation, and characteristics
Nutrition in Pregnancy and Growth in Southwest China (NPGSC) cohort: Design, implementation, and characteristics Open
Background Pregnancy and birth cohorts addressing maternal nutrition and its impact on health outcomes have been rare in China, especially in Southwest China. Objectives To describe the design, implementation, baseline characteristics, and…
View article: Sedentary Behavior Is Independently Related to Fat Mass among Children and Adolescents in South China
Sedentary Behavior Is Independently Related to Fat Mass among Children and Adolescents in South China Open
We aim to explore the independent associations of sedentary behaviors (SB) with body mass distribution among Chinese children. Data on the screen-based sedentary time (television viewing and computer use) and doing homework, physical activ…
View article: Development of a Dietary Index to Assess Overall Diet Quality for Chinese School-Aged Children: The Chinese Children Dietary Index
Development of a Dietary Index to Assess Overall Diet Quality for Chinese School-Aged Children: The Chinese Children Dietary Index Open
View article: The Cross-Sectional Association of Energy Intake and Dietary Energy Density with Body Composition of Children in Southwest China
The Cross-Sectional Association of Energy Intake and Dietary Energy Density with Body Composition of Children in Southwest China Open
Objective: We examined whether dietary energy intake (EI) and dietary energy density (ED) were cross-sectionally associated with body composition of children living in Southwest China. Design and Methods: Multivariate regression analyses w…