Rupam Borgohain
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View article: Saving the parathyroid during thyroid surgery and its impact on quality of life: A surgical challenge
Saving the parathyroid during thyroid surgery and its impact on quality of life: A surgical challenge Open
View article: Conceptualizing a Personalized Care Pathway for Parkinson’s Disease Using Wearable Sensors in Muslim Patients: The Ramadan Regimen
Conceptualizing a Personalized Care Pathway for Parkinson’s Disease Using Wearable Sensors in Muslim Patients: The Ramadan Regimen Open
Parkinson's disease (PD) affects approximately 2% of individuals over the age of 60. With over two billion Muslims observing Ramadan, individuals with PD encounter specific challenges, such as deteriorating motor skills, sleep disturbances…
View article: Association of Bassoon (BSN) Gene Mutations with Gait and Motor Impairments in Parkinson's Disease
Association of Bassoon (BSN) Gene Mutations with Gait and Motor Impairments in Parkinson's Disease Open
Introduction Parkinson's Disease (PD) features debilitating motor symptoms, particularly gait and balance impairments inadequately managed by current therapies. Bassoon (BSN), a presynaptic active zone organizer, has been implicated in var…
View article: Demographic and Clinical Profiles of Parkinson's Disease in India: Observations from a Nation‐Wide Multicenter Study
Demographic and Clinical Profiles of Parkinson's Disease in India: Observations from a Nation‐Wide Multicenter Study Open
Background Parkinson's disease (PD) phenotype may vary with genetic, ethno‐geographic, cultural, and environmental factors. Objectives The aim was to develop a clinical database of PD in India and assess the influence of age‐at‐onset (AAO)…
View article: MRI-Guided Focused Ultrasound in Parkinson’s Disease and Essential Tremor: Incisionless but Invasive. A Narrative Review
MRI-Guided Focused Ultrasound in Parkinson’s Disease and Essential Tremor: Incisionless but Invasive. A Narrative Review Open
Magnetic resonance-guided focused ultrasound (MRgFUS) is an emerging and promising technology for treating movement disorders, such as essential tremors and tremor-dominant Parkinson’s disease. MRgFUS utilizes advanced ultrasound transduce…
View article: The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population
The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population Open
View article: Delayed Normal Pressure Hydrocephalus after Deep Brain Stimulation in Parkinson's Disease
Delayed Normal Pressure Hydrocephalus after Deep Brain Stimulation in Parkinson's Disease Open
Background Deep brain stimulation (DBS) of the bilateral subthalamic nuclei (STN) or globus pallidus internus (GPi) for Parkinson's disease (PD) and dystonia is known for its efficacy despite potential complications. Although acute complic…
View article: Deciphering the Genetic Architecture of Parkinson’s Disease in India
Deciphering the Genetic Architecture of Parkinson’s Disease in India Open
The genomic landscape of the Indian population, particularly for age-related disorders like Parkinson’s disease (PD) remains underrepresented in global research. Genetic variability in PD has been studied predominantly in European populati…
View article: Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia
Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia Open
Background Dexamethasone sodium phosphate (DSP) encapsulated in autologous erythrocytes (EryDex) was developed as an alternative to standard glucocorticoids in an effort to eliminate chronic steroid toxicity while preserving efficacy. The …
View article: Clinical Efficacy, Cost Effectiveness, and Caregiver Satisfaction of the Application of Parkinson's Kinetigraph (PKG) in Clinical Practice Versus Standard Care – A 12-Month Longitudinal Analysis Part of the EmPARK-PKG Project
Clinical Efficacy, Cost Effectiveness, and Caregiver Satisfaction of the Application of Parkinson's Kinetigraph (PKG) in Clinical Practice Versus Standard Care – A 12-Month Longitudinal Analysis Part of the EmPARK-PKG Project Open
View article: Progressive Supranuclear Palsy in India: Past, Present, and Future
Progressive Supranuclear Palsy in India: Past, Present, and Future Open
Progressive supranuclear palsy (PSP) has emerged as a key area of interest among researchers worldwide, including those in India, who have actively studied the disorder over the past several decades. This review meticulously explores the e…
View article: The first cross-sectional comparative observational study of sexual dysfunction in Emirati and non-Emirati Parkinson’s disease patients (EmPark-SD) in the United Arab Emirates
The first cross-sectional comparative observational study of sexual dysfunction in Emirati and non-Emirati Parkinson’s disease patients (EmPark-SD) in the United Arab Emirates Open
Sexual dysfunction (SD) is a common non-motor symptom in people with Parkinson's disease (PD) yet underreported and undertreated specifically in many ethnic PD groups because of religious, social and personal perceptions. We conducted the …
View article: The First cross-sectional comparative observational study of sexual dysfunction in Emirati and non-Emirati Parkinson’s disease Patients (EmPark-SD) in the UAE?
The First cross-sectional comparative observational study of sexual dysfunction in Emirati and non-Emirati Parkinson’s disease Patients (EmPark-SD) in the UAE? Open
Sexual dysfunction (SD) is common non-motor symptom in people with Parkinson’s disease (PD) yet underreported and undertreated specifically in many ethnic PD groups because of religious, social and personal perceptions. We conducted the fi…
View article: Impact of Duration of Parkinsonism and Antiparkinsonian Drugs on Coagulation Parameters in Patients with Parkinson’s Disease
Impact of Duration of Parkinsonism and Antiparkinsonian Drugs on Coagulation Parameters in Patients with Parkinson’s Disease Open
Background and Objectives: Parkinson’s disease (PD) is a neurodegenerative disorder involving depletion of dopaminergic neurons. Pathogenetic mechanisms leading to striatonigral degeneration are debatable. Chronic inflammation is proposed …
View article: Levodopa Equivalent Daily Dosage: Geographical Variations and Real‐Life Modules in Parkinson's Disease
Levodopa Equivalent Daily Dosage: Geographical Variations and Real‐Life Modules in Parkinson's Disease Open
Background The Levodopa Equivalent Daily Dosage (LEDD) calculation algorithms help in capturing and harmonization of Parkinson's Disease (PD) therapies. Analyzing these updates is essential for validating their effectiveness. Objective To …
View article: Safety and efficacy of intra-erythrocyte dexamethasone sodium phosphate in children with ataxia telangiectasia (ATTeST): a multicentre, randomised, double-blind, placebo-controlled phase 3 trial
Safety and efficacy of intra-erythrocyte dexamethasone sodium phosphate in children with ataxia telangiectasia (ATTeST): a multicentre, randomised, double-blind, placebo-controlled phase 3 trial Open
View article: Editorial: New insights in non-motor symptoms in Parkinson's disease
Editorial: New insights in non-motor symptoms in Parkinson's disease Open
Cristian Falup-Pecurariu1,2*Alessandra Fanciulli3Rupam Borgohain4Vinod Metta5,6,7K. Ray Chaudhuri5,6
View article: The Pattern of Bacterial Infections Among Chronic Suppurative Otitis Media Cases at a Tertiary Care Centre in North-East India
The Pattern of Bacterial Infections Among Chronic Suppurative Otitis Media Cases at a Tertiary Care Centre in North-East India Open
View article: Prof. Kapil Dev Sethi: Loss of a brilliant and ever-inspiring mentor to movement disorder researchers
Prof. Kapil Dev Sethi: Loss of a brilliant and ever-inspiring mentor to movement disorder researchers Open
View article: The impact of bilateral subthalamic nucleus deep brain stimulation on dyskinesia and levodopa equivalent daily dose in advanced Parkinson’s disease
The impact of bilateral subthalamic nucleus deep brain stimulation on dyskinesia and levodopa equivalent daily dose in advanced Parkinson’s disease Open
OBJECTIVE: To assess the effect of bilateral subthalamic nucleus deep brain stimulation (B/L STN DBS) on the progression of dyskinesia and the levodopa equivalent daily dose (LEDD) in advanced Parkinson’s disease (APD) patients 6 months po…
View article: Complications of thyroidectomy: Insights from a single-centre study in northeast India
Complications of thyroidectomy: Insights from a single-centre study in northeast India Open
To study and compare the frequency of post-operative complications associated with thyroid surgeries indicated for various benign and malignant pathologies and assess the outcome of management of such complications in a tertiary care hospi…
View article: New insights in non-motor symptoms in Parkinson’s disease
New insights in non-motor symptoms in Parkinson’s disease Open
it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed.The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge.Front…
View article: Adult-Onset Neuronal Ceroid Lipofuscinosis: CLN5 Variant Presenting as Focal Dystonia
Adult-Onset Neuronal Ceroid Lipofuscinosis: CLN5 Variant Presenting as Focal Dystonia Open
Isolated focal dystonia has not been reported as an initial presentation in ANCL. Early genetic testing and periodic clinical assessments are advisable for better management and prognostication.
View article: SPG7 mutation – Novel phenotypic presentation mimicking idiopathic Parkinson’s disease
SPG7 mutation – Novel phenotypic presentation mimicking idiopathic Parkinson’s disease Open
• SPG7 mutations can present as asymmetric parkinsonism mimicking idiopathic Parkinson’s disease, • SPG7 mutation must be considered in Early onset Parkinson’s disease even with a negative family history. • Parkinsonism with SPG7 mutations…
View article: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Effects of Intra-Erythrocyte Dexamethasone Sodium Phosphate (EryDex) on Neurological Symptoms in Patients with Ataxia-Telangiectasia (ATTeST)
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Effects of Intra-Erythrocyte Dexamethasone Sodium Phosphate (EryDex) on Neurological Symptoms in Patients with Ataxia-Telangiectasia (ATTeST) Open
View article: The First Cross-Sectional Comparative Observational Study of Sexual Dysfunction in Emirati and Non-Emirati Parkinson's Disease Patients (EmPark-SD) in the UAE?
The First Cross-Sectional Comparative Observational Study of Sexual Dysfunction in Emirati and Non-Emirati Parkinson's Disease Patients (EmPark-SD) in the UAE? Open
View article: Delayed Peri-Lead Intracerebral Hemorrhage Months after Deep Brain Stimulation: A Series of Two Patients
Delayed Peri-Lead Intracerebral Hemorrhage Months after Deep Brain Stimulation: A Series of Two Patients Open
Yaranagula, Sai Deepak; Kashyap, Manshi; Kola, Sruthi; Kandadai, Rukmini Mridula; Alugolu, Rajesh; Prasad, Vanakuru; Jasani, Garima Atulkumar; Borgohain, Rupam; Varma, Ravi Dandu Author Information
View article: Complex Movement Disorder with Prominent Tic like Movements: Expanding the Clinical Spectrum of <scp>IgLON</scp> 5 Antibody Disease
Complex Movement Disorder with Prominent Tic like Movements: Expanding the Clinical Spectrum of <span>IgLON</span> 5 Antibody Disease Open
View article: Safety and tolerability of long-term apomorphine infusion in advanced Parkinson's disease: an Indian multi-center (APO-IND) experience
Safety and tolerability of long-term apomorphine infusion in advanced Parkinson's disease: an Indian multi-center (APO-IND) experience Open
Advanced Parkinson’s Disease (APD) is complicated by the emergence of motor and non-motor fluctuations, which are initially predictable and eventually become unpredictable, in part due to erratic gastric absorption and short half of oral l…
View article: Aceruloplasminemia with Novel Mutation, with IgG4 Related Pachymeningitis – Occam’s Razor or Hickam’s Dictum?
Aceruloplasminemia with Novel Mutation, with IgG4 Related Pachymeningitis – Occam’s Razor or Hickam’s Dictum? Open
To report a patient with concomitant aceruloplasminemia (with a novel mutation) and IgG4-related pachymeningitis and to hypothesize on the possible relation between the two diseases. Clinical, radiological, and laboratory features of a 56-…