Rushui Bai
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View article: Design of periodontitis vaccine: Target, adjuvant, and delivery system
Design of periodontitis vaccine: Target, adjuvant, and delivery system Open
Periodontitis is a chronic, progressive, destructive disease that can cause tooth loss. There are some limitations in controlling plaques through mechanical removal and drug therapy using traditional treatments. In recent years, attention …
View article: Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances
Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances Open
The oral microbiome plays an important role in human health, and an imbalance of the oral microbiome could lead to oral and systemic diseases. Orthodontic treatment is an effective method to correct malocclusion. However, it is associated …
View article: Tooth movement with clear aligners with different elastic modulus: a three-dimensional finite element analysis
Tooth movement with clear aligners with different elastic modulus: a three-dimensional finite element analysis Open
Background Compared with traditional fixed appliances, clear aligners (CAs) still lack the ability to accurately control the three-dimensional tooth movement. The present study was devoted to the comparison of treatment outcomes of CAs dia…
View article: Colon-targeted Engineered Postbiotics Nanoparticles Alleviating Osteoporosis through Gut-Bone Axis
Colon-targeted Engineered Postbiotics Nanoparticles Alleviating Osteoporosis through Gut-Bone Axis Open
The potential for mitigating intestinal inflammation through the gut-bone axis in the treatment of osteoporosis is significant. While various gut-derived postbiotics or bacterial metabolites have been created as dietary supplements to prev…
View article: Lysine 68 Methylation‐Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells
Lysine 68 Methylation‐Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells Open
Dental pulp stem cells (DPSCs), characterized by easy availability, multi‐lineage differentiation ability, and high proliferation ability, are ideal seed cells for cartilage tissue engineering. However, the epigenetic mechanism underlying …
View article: Lysine demethylase 3A promotes chondrogenic differentiation of aged human dental pulp stem cells
Lysine demethylase 3A promotes chondrogenic differentiation of aged human dental pulp stem cells Open
Our findings indicate that KDM3A plays an important role in the maintenance of the chondrogenic differentiation capacity of aged hDPSCs and suggest that therapies targeting KDM3A may be a novel strategy to rejuvenate aged hDPSCs.
View article: Mechanically Robust Hydrogels Facilitating Bone Regeneration through Epigenetic Modulation
Mechanically Robust Hydrogels Facilitating Bone Regeneration through Epigenetic Modulation Open
Development of artificial biomaterials by mimicking extracellular matrix of bone tissue is a promising strategy for bone regeneration. Hydrogel has emerged as a type of viable substitute, but its inhomogeneous networks and weak mechanics g…
View article: Progress of Nanomaterials-Based Photothermal Therapy for Oral Squamous Cell Carcinoma
Progress of Nanomaterials-Based Photothermal Therapy for Oral Squamous Cell Carcinoma Open
Oral squamous cell carcinoma (OSCC) is one of the top 15 most prevalent cancers worldwide. However, the current treatment models for OSCC (e.g., surgery, chemotherapy, radiotherapy, and combination therapy) present several limitations: dam…
View article: Bio-inspired special wettability in oral antibacterial applications
Bio-inspired special wettability in oral antibacterial applications Open
Most oral diseases originate from biofilms whose formation is originated from the adhesion of salivary proteins and pioneer bacteria. Therefore, antimicrobial materials are mainly based on bactericidal methods, most of which have drug resi…
View article: Ceramic Toughening Strategies for Biomedical Applications
Ceramic Toughening Strategies for Biomedical Applications Open
Aiming at shortage of metal materials, ceramic is increasingly applied in biomedicine due to its high strength, pleasing esthetics and good biocompatibility, especially for dental restorations and implants, artificial joints, as well as sy…
View article: Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives
Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives Open
Repairing tooth defects with dental resin composites is currently the most commonly used method due to their tooth-colored esthetics and photocuring properties. However, the higher than desirable failure rate and moderate service life are …
View article: Metallic Antibacterial Surface Treatments of Dental and Orthopedic Materials
Metallic Antibacterial Surface Treatments of Dental and Orthopedic Materials Open
The oral cavity harbors complex microbial communities, which leads to biomaterial-associated infections (BAI) during dental and orthopedic treatments. Conventional antibiotic treatments have met great challenges recently due to the increas…