Russell Chabanne
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View article: Dexmedetomidine for treatment of hyperactive delirium in non-intubated ICU patients: the 4D randomized clinical trial
Dexmedetomidine for treatment of hyperactive delirium in non-intubated ICU patients: the 4D randomized clinical trial Open
View article: Impact of Visitation Restrictions in ICU on Psychological Symptoms in Family Members: Experience of the COVID-19 Pandemic
Impact of Visitation Restrictions in ICU on Psychological Symptoms in Family Members: Experience of the COVID-19 Pandemic Open
This study does not support the hypothesis that visitation restriction policies during the COVID-19 pandemic exacerbated high prevalence of long-term psychological symptoms among ICU family members. This article is open access and distribu…
View article: Prevention of extubation failure in neurocritical care patients with residual disorder of consciousness: the Brain-Injured Patients Extubation Readiness (BIPER) study protocol for a stepped-wedge cluster-randomised controlled trial
Prevention of extubation failure in neurocritical care patients with residual disorder of consciousness: the Brain-Injured Patients Extubation Readiness (BIPER) study protocol for a stepped-wedge cluster-randomised controlled trial Open
Introduction In the intensive care unit (ICU), brain-injured patients are frequently exposed to mechanical ventilation to protect the brain and preserve physiology. After intracranial pressure control and sedation withdrawal, this populati…
View article: In vivo testing of the Pressio intracranial pressure monitor: the EPIC study
In vivo testing of the Pressio intracranial pressure monitor: the EPIC study Open
Objective Measuring reliable intracranial pressure (ICP) is critical for patients with acute brain injuries. The aim of this study was to evaluate zero-drift of the intra-parenchymal strain gauge Pressio transducer (Sophysa, Orsay, France)…
View article: Cerebral compliance assessment from intracranial pressure waveform analysis: Is a positional shift-related increase in intracranial pressure predictable?
Cerebral compliance assessment from intracranial pressure waveform analysis: Is a positional shift-related increase in intracranial pressure predictable? Open
Real-time monitoring of intracranial pressure (ICP) is a routine part of neurocritical care in the management of brain injury. While mainly used to detect episodes of intracranial hypertension, the ICP signal is also indicative of the volu…
View article: Intracranial multimodal monitoring in neurocritical care (Neurocore-iMMM): an open, decentralized consensus
Intracranial multimodal monitoring in neurocritical care (Neurocore-iMMM): an open, decentralized consensus Open
This consensus establishes foundational COS and reporting guidelines for iMMM in neurocritical care. These harmonization tools can enhance research quality, comparability, and reproducibility, facilitating evidence-based practices for this…
View article: CSF pharmacokinetics-pharmacodynamics of linezolid in critically brain injured patients, with or without central nervous system healthcare-associated infection. The PK-Pop-LCR Study: A Multicenter Pharmacokinetics and Pharmacodynamics Population Study
CSF pharmacokinetics-pharmacodynamics of linezolid in critically brain injured patients, with or without central nervous system healthcare-associated infection. The PK-Pop-LCR Study: A Multicenter Pharmacokinetics and Pharmacodynamics Population Study Open
Linezolid is an alternative to vancomycin for treating Gram-positive central nervous system (CNS) healthcare-associated infections. The recommended dosing regimen remains debated. PK-Pop-LCR is a prospective population pharmacokinetic-phar…
View article: Weaning of non COPD patients at high-risk of extubation failure assessed by lung ultrasound: the WIN IN WEAN multicentre randomised controlled trial
Weaning of non COPD patients at high-risk of extubation failure assessed by lung ultrasound: the WIN IN WEAN multicentre randomised controlled trial Open
View article: REACT: a randomized trial to assess the efficacy and safety of clazosentan for preventing clinical deterioration due to delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
REACT: a randomized trial to assess the efficacy and safety of clazosentan for preventing clinical deterioration due to delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage Open
OBJECTIVE Ischemic complications account for significant patient morbidity following aneurysmal subarachnoid hemorrhage (aSAH). The Prevention and Treatment of Vasospasm with Clazosentan (REACT) study was designed to assess the safety and …
View article: Cost awareness among intensivists in their daily clinical practice: a prospective multicentre study
Cost awareness among intensivists in their daily clinical practice: a prospective multicentre study Open
Background Better cost-awareness is a prerogative in achieving the best benefit/risk/cost ratio in the care. We aimed to assess the cost-awareness of intensivists in their daily clinical practice and to identify factors associated with acc…
View article: Correction: Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study
Correction: Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study Open
View article: Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study
Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study Open
View article: Body composition and muscle strength at the end of ICU stay are associated with one-year mortality, a prospective multicenter observational study
Body composition and muscle strength at the end of ICU stay are associated with one-year mortality, a prospective multicenter observational study Open
View article: Body composition and muscle strength at the end of ICU stay are associated with 1-year mortality, a prospective multicenter observational study
Body composition and muscle strength at the end of ICU stay are associated with 1-year mortality, a prospective multicenter observational study Open
BIA to assess FFMI, HG and albuminemia at the end of ICU stay could be used to predict 1-year mortality. Their ability to identify patients eligible for a structured recovery program could be studied.
View article: Thoracic epidural analgesia in intensive care unit patients with acute pancreatitis: the EPIPAN multicenter randomized controlled trial
Thoracic epidural analgesia in intensive care unit patients with acute pancreatitis: the EPIPAN multicenter randomized controlled trial Open
View article: Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies in neuro-intensive care unit patients and associations with outcome (ENIO) trial
Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies in neuro-intensive care unit patients and associations with outcome (ENIO) trial Open
View article: Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study
Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study Open
View article: Outcomes After Endovascular Therapy With Procedural Sedation vs General Anesthesia in Patients With Acute Ischemic Stroke
Outcomes After Endovascular Therapy With Procedural Sedation vs General Anesthesia in Patients With Acute Ischemic Stroke Open
Importance General anesthesia and procedural sedation are common practice for mechanical thrombectomy in acute ischemic stroke. However, risks and benefits of each strategy are unclear. Objective To determine whether general anesthesia or …
View article: Electroencephalography for prognostication of outcome in adults with severe herpes simplex encephalitis
Electroencephalography for prognostication of outcome in adults with severe herpes simplex encephalitis Open
Background Electroencephalography (EEG) is recommended for the practical approach to the diagnosis and prognosis of encephalitis. We aimed to investigate the prognostic value of standard EEG ( std EEG) in adult patients with severe herpes …
View article: Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients
Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients Open
View article: Effect of an individualized versus standard blood pressure management during mechanical thrombectomy for anterior ischemic stroke: the DETERMINE randomized controlled trial
Effect of an individualized versus standard blood pressure management during mechanical thrombectomy for anterior ischemic stroke: the DETERMINE randomized controlled trial Open
View article: Assessment of Magnetic Resonance Imaging Changes and Functional Outcomes Among Adults With Severe Herpes Simplex Encephalitis
Assessment of Magnetic Resonance Imaging Changes and Functional Outcomes Among Adults With Severe Herpes Simplex Encephalitis Open
These findings suggest that in adult patients with HSE requiring ICU admission, extensive MRI changes in the brain are independently associated with poor functional outcome at 90 days. Thalamic diffusion signal changes were frequently obse…
View article: Continuous Pneumatic Regulation of Tracheal Cuff Pressure to Decrease Ventilator-associated Pneumonia in Trauma Patients Who Were Mechanically Ventilated
Continuous Pneumatic Regulation of Tracheal Cuff Pressure to Decrease Ventilator-associated Pneumonia in Trauma Patients Who Were Mechanically Ventilated Open
View article: Impact of advance directives on the variability between intensivists in the decisions to forgo life-sustaining treatment
Impact of advance directives on the variability between intensivists in the decisions to forgo life-sustaining treatment Open
View article: Anaesthesia and haemodynamic management of acute ischaemic stroke patients before, during and after endovascular therapy
Anaesthesia and haemodynamic management of acute ischaemic stroke patients before, during and after endovascular therapy Open
View article: Epidural analgesia in ICU chest trauma patients with fractured ribs: retrospective study of pain control and intubation requirements
Epidural analgesia in ICU chest trauma patients with fractured ribs: retrospective study of pain control and intubation requirements Open
View article: Sedation versus general anaesthesia in endovascular therapy for anterior circulation acute ischaemic stroke: the multicentre randomised controlled AMETIS trial study protocol
Sedation versus general anaesthesia in endovascular therapy for anterior circulation acute ischaemic stroke: the multicentre randomised controlled AMETIS trial study protocol Open
Introduction Endovascular thrombectomy is the standard of care for anterior circulation acute ischaemic stroke (AIS) secondary to emergent large vessel occlusion in patients who qualify. General anaesthesia (GA) or conscious sedation (CS) …
View article: Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study
Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study Open
View article: Measurement of S100B protein: evaluation of a new prototype on a bioMérieux Vidas<sup>®</sup> 3 analyzer
Measurement of S100B protein: evaluation of a new prototype on a bioMérieux Vidas<sup>®</sup> 3 analyzer Open
Background The addition of S100B protein to guidelines for the management of mild traumatic brain injury (mTBI) decreases the amount of unnecessary computed tomography (CT) scans with a significant decrease in radiation exposure and an inc…
View article: Driving pressure and acute respiratory distress syndrome in critically ill patients
Driving pressure and acute respiratory distress syndrome in critically ill patients Open
Background and objective Elevated driving pressure (ΔP) may be associated with increased risk of acute respiratory distress syndrome (ARDS) in patients admitted via the emergency department and with post‐operative pulmonary complications i…