R. Rowland
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View article: Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice.
Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice. Open
Previously we described activating mutations of hbetac, the common signaling subunit of the receptors for the hematopoietic and inflammatory cytokines, GM-CSF, IL-3, and IL-5. The activated mutant, hbetacFIDelta, is able to confer growth f…
View article: HYDROGEN SULPHIDE PRODUCES DIMINISHED FATTY ACID OXIDATION IN THE RAT COLON <i>IN VIVO</i>: IMPLICATIONS FOR ULCERATIVE COLITIS
HYDROGEN SULPHIDE PRODUCES DIMINISHED FATTY ACID OXIDATION IN THE RAT COLON <i>IN VIVO</i>: IMPLICATIONS FOR ULCERATIVE COLITIS Open
Background : Several lines of evidence suggest a possible role for reduced forms of sulphur (including sulphide) in ulcerative colitis. The aims of this study were to assess the metabolic profile of colonic epithelial cells after treatment…
View article: Activity of duodenal disaccharidases in relation to normal and abnormal mucosal morphology.
Activity of duodenal disaccharidases in relation to normal and abnormal mucosal morphology. Open
Endoscopic duodenal biopsy specimens from 100 predominantly adult Caucasian patients under investigation for gastrointestinal symptoms were used to establish reference ranges for lactase, sucrase, and maltase in the duodenum. Duodenal and …
View article: Quantitative histological study of enteropathy associated with HIV infection.
Quantitative histological study of enteropathy associated with HIV infection. Open
A quantitative histological study was performed on small intestinal biopsies from eight ambulatory patients with HIV infection (AIDS/AIDS-related complex, ARC) and compared with those from 16 normal subjects. Enteropathy was assessed by me…
View article: The microscopic distribution of 99mTc‐labelled phagocytes in resected bowel in patients with acute Crohn's disease: correlation with histological changes
The microscopic distribution of 99mTc‐labelled phagocytes in resected bowel in patients with acute Crohn's disease: correlation with histological changes Open
Abdominal scintiscans performed after the injection of autologous phagocytes labelled with 99m Tc‐stannous colloid particles provide an accurate assessment of the extent of disease in active inflammatory bowel disease. To study the correla…
View article: Collagenous colitis: a distinctive and potentially reversible disorder.
Collagenous colitis: a distinctive and potentially reversible disorder. Open
A case of collagenous colitis is reported. The patient's symptoms cleared up after a course of mepacrine hydrochloride. Biopsies taken after clinical recovery still showed some increase in the number of reticulin fibres present in the uppe…
View article: Alpha1-fetoprotein in the diagnosis of hepatoma: statistical and cost benefit aspects.
Alpha1-fetoprotein in the diagnosis of hepatoma: statistical and cost benefit aspects. Open
A rational comparison of different serum concentrations of alpha1-fetoprotein (S-AFP) in the diagnosis of hepatoma must be made. We took data on the sensitivity and specificity of different diagnostic S-AFP concentrations from the literatu…
View article: Immunoglobulin-bearing cells in giardiasis.
Immunoglobulin-bearing cells in giardiasis. Open
composition is as follows (g/litre): special peptone (Oxoid L72) 23-0; soluble starch 10-0; NaH2PO4, 2H2O 0-873; Na2HPO4 2 044; bromocresol purple 0 030; phenol red 0-024; agar (Oxoid No. 1) 10-0; distilled water to 1 litre.The medium (whi…