Ruxandra Christodorescu
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View article: From consensus to action: Implementing cardiovascular prevention guidelines in primary healthcare
From consensus to action: Implementing cardiovascular prevention guidelines in primary healthcare Open
Cardiovascular prevention guidelines are based on robust evidence, yet their implementation in primary healthcare remains inconsistent due to systemic barriers, workload pressures and insufficiently adapted tools. The 2025 European consens…
View article: Cardiovascular risk factors management in older adults: a clinical consensus statement from the European Association of Preventive Cardiology of the ESC and the ESC Council for Cardiology Practice
Cardiovascular risk factors management in older adults: a clinical consensus statement from the European Association of Preventive Cardiology of the ESC and the ESC Council for Cardiology Practice Open
Cardiovascular disease (CVD) currently ranks first in global mortality and morbidity and its prevalence increases with age. The most common risk factors for CVD are hypertension, diabetes mellitus, dyslipidaemias, adipositas, smoking, and …
View article: Atherosclerosis and Insulin Resistance: Is There a Link Between Them?
Atherosclerosis and Insulin Resistance: Is There a Link Between Them? Open
Cardiovascular disease remains the leading cause of morbidity and mortality worldwide, especially in regions like Eastern Europe, South Asia, and Latin America. A significant portion of these cases (80%) is linked to atherosclerosis, which…
View article: Is It Safe to Initiate/Optimize the Medication of HFrEF Patients During Hospitalization for Acute Decompensation?
Is It Safe to Initiate/Optimize the Medication of HFrEF Patients During Hospitalization for Acute Decompensation? Open
Background: Current guidelines emphasize the importance of initiating or optimizing the four pillars of heart failure with reduced ejection fraction (HFrEF) therapy—beta-blockers (BB), mineralocorticoid receptor antagonists (MRA), angioten…
View article: Key priorities for the implementation of the 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes in low-resource settings
Key priorities for the implementation of the 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes in low-resource settings Open
ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, particularly in low-resource sett…
View article: Cardiovascular diseases, prevention, and management of complications in older adults and frail patients treated for elective or post-traumatic hip orthopaedic interventions: a clinical consensus statement of the ESC Council for Cardiology Practice (CCP), the European Association of Preventive Cardiology (EAPC), the Association for Acute CardioVascular Care (ACVC), the Association of Cardiovascular Nursing & Allied Professions of the ESC (ACNAP), the ESC Working Group on Aorta and Peripheral Vascular Diseases (WG APVD), and the ESC Working Group on Thrombosis (WG T)
Cardiovascular diseases, prevention, and management of complications in older adults and frail patients treated for elective or post-traumatic hip orthopaedic interventions: a clinical consensus statement of the ESC Council for Cardiology Practice (CCP), the European Association of Preventive Cardiology (EAPC), the Association for Acute CardioVascular Care (ACVC), the Association of Cardiovascular Nursing & Allied Professions of the ESC (ACNAP), the ESC Working Group on Aorta and Peripheral Vascular Diseases (WG APVD), and the ESC Working Group on Thrombosis (WG T) Open
Due to the aging population, focusing on healthy aging has become a global priority. Cardiovascular diseases (CVDs) and frailty, characterized by increased vulnerability to adverse stress and health events, interact synergistically in adva…
View article: Clinical and Demographic Characteristics of Patients Hospitalized for Decompensated Heart Failure with Extremely High NT-proBNP Levels
Clinical and Demographic Characteristics of Patients Hospitalized for Decompensated Heart Failure with Extremely High NT-proBNP Levels Open
Background: NT-proBNP levels with a wide range at admission play both a diagnostic and a prognostic role in patients with HF. The differences regarding the clinical profiles and demography in decompensated HF patients according to NT-proBN…
View article: 2024 ESC Guidelines for the management of chronic coronary syndromes
2024 ESC Guidelines for the management of chronic coronary syndromes Open
View article: 2024 ESC Guidelines for the management of elevated blood pressure and hypertension
2024 ESC Guidelines for the management of elevated blood pressure and hypertension Open
View article: Standardized assessment of evidence supporting the adoption of mobile health solutions: A Clinical Consensus Statement of the ESC Regulatory Affairs Committee
Standardized assessment of evidence supporting the adoption of mobile health solutions: A Clinical Consensus Statement of the ESC Regulatory Affairs Committee Open
Mobile health (mHealth) solutions have the potential to improve self-management and clinical care. For successful integration into routine clinical practice, healthcare professionals (HCPs) need accepted criteria helping the mHealth soluti…
View article: A Low-Cost Protocol Using the Adjunctive Action of Povidone–Iodine Irrigations and Sodium Hypochlorite Rinsing Solution in Step 2 of Periodontal Therapy for Patients with Stage III–IV Periodontitis: A Single-Blind, Randomized Controlled Trial
A Low-Cost Protocol Using the Adjunctive Action of Povidone–Iodine Irrigations and Sodium Hypochlorite Rinsing Solution in Step 2 of Periodontal Therapy for Patients with Stage III–IV Periodontitis: A Single-Blind, Randomized Controlled Trial Open
In severe stages of periodontitis, conventional periodontal therapy and maintenance care are usually insufficient due to the viral and bacterial etiology; thus, a mechanical approach alone may not be sufficient to eliminate a substantial p…
View article: Physician perceptions, attitudes, and strategies towards implementing guideline‐directed medical therapy in heart failure with reduced ejection fraction. A survey of the Heart Failure Association of the <scp>ESC</scp> and the <scp>ESC</scp> Council for Cardiology Practice
Physician perceptions, attitudes, and strategies towards implementing guideline‐directed medical therapy in heart failure with reduced ejection fraction. A survey of the Heart Failure Association of the <span>ESC</span> and the <span>ESC</span> Council for Cardiology Practice Open
Aims Recent guidelines recommend four core drug classes (renin–angiotensin system inhibitor/angiotensin receptor–neprilysin inhibitor [RASi/ARNi], beta‐blocker, mineralocorticoid receptor antagonist [MRA], and sodium–glucose cotransporter …
View article: Practical algorithms for early diagnosis of heart failure and heart stress using <scp>NT‐proBNP</scp>: A clinical consensus statement from the Heart Failure Association of the <scp>ESC</scp>
Practical algorithms for early diagnosis of heart failure and heart stress using <span>NT‐proBNP</span>: A clinical consensus statement from the Heart Failure Association of the <span>ESC</span> Open
Diagnosing heart failure is often difficult due to the non‐specific nature of symptoms, which can be caused by a range of medical conditions. Natriuretic peptides (NPs) have been recognized as important biomarkers for diagnosing heart fail…
View article: 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes Open
Guidelines evaluate and summarize available evidence, with the aim of assisting health professionals in proposing the best diagnostic or therapeutic approach for an individual patient with a given condition. Guidelines are intended for use…
View article: Is the Diagnosis of Generalized Stage IV (Severe) Periodontitis Compatible with the Survival of Extended Stabilizing Prosthetic Restorations? A Medium-Term Retrospective Study
Is the Diagnosis of Generalized Stage IV (Severe) Periodontitis Compatible with the Survival of Extended Stabilizing Prosthetic Restorations? A Medium-Term Retrospective Study Open
The aim of the study was to identify the most relevant patient-related factors directly involved (alone or in combinations) in the long-term survival and functionality of the abutment teeth of extensive stabilizing bridges and removable pr…
View article: Digital health in older adults for the prevention and management of cardiovascular diseases and frailty. <i>A clinical consensus statement from the ESC Council for Cardiology Practice/Taskforce on Geriatric Cardiology, the ESC Digital Health Committee and the ESC Working Group on e‐Cardiology</i>
Digital health in older adults for the prevention and management of cardiovascular diseases and frailty. <i>A clinical consensus statement from the ESC Council for Cardiology Practice/Taskforce on Geriatric Cardiology, the ESC Digital Health Committee and the ESC Working Group on e‐Cardiology</i> Open
Digital health technology is receiving increasing attention in cardiology. The rise of accessibility of digital health tools including wearable technologies and smart phone applications used in medical practice has created a new era in hea…
View article: Cardiovascular Risk Prediction Parameters for Better Management in Rheumatic Diseases
Cardiovascular Risk Prediction Parameters for Better Management in Rheumatic Diseases Open
The early detection of cardiovascular disease (CVD) serves as a key element in preventive cardiology. The risk of developing CVD in patients with rheumatic disease is higher than that of the general population. Thus, the objective of this …
View article: Periodontitis in Ischemic Stroke Patients: Case Definition Challenges of the New Classification Scheme (2018)
Periodontitis in Ischemic Stroke Patients: Case Definition Challenges of the New Classification Scheme (2018) Open
The identification of the associative relationships between ischemic stroke (IS) and risk factors such as advanced age and periodontitis is essential to design real screening protocols and to address them using primary and secondary preven…
View article: Contribution of Global and Regional Longitudinal Strain for Clinical Assessment of HFpEF in Coronary and Hypertensive Patients
Contribution of Global and Regional Longitudinal Strain for Clinical Assessment of HFpEF in Coronary and Hypertensive Patients Open
Background: Contribution of global and regional longitudinal strain (GLS) for clinical assessment of patients with heart failure with preserved ejection fraction (HFpEF) is not well established. We sought to evaluate subclinical left ventr…
View article: Assessment of the Impact of Alcohol Consumption Patterns on Heart Rate Variability by Machine Learning in Healthy Young Adults
Assessment of the Impact of Alcohol Consumption Patterns on Heart Rate Variability by Machine Learning in Healthy Young Adults Open
Background and Objectives: Autonomic nervous system (ANS) dysfunction is present in early stages of alcohol abuse and increases the likelihood of cardiovascular events. Given the nonlinear pattern of dynamic interaction between sympathetic…
View article: Late phase of COVID‐19 pandemic in General Cardiology. A position paper of the ESC Council for Cardiology Practice
Late phase of COVID‐19 pandemic in General Cardiology. A position paper of the ESC Council for Cardiology Practice Open
Cardiovascular (CV) engagement in coronavirus disease 2019 (COVID‐19) is a huge determinant of prognosis during the acute phase of the disease. However, little is known about the potential chronic implications of the late phase of COVID‐19…
View article: Survey on e-health knowledge and usage in general cardiology of the Council of Cardiology Practice and the Digital Health Committee
Survey on e-health knowledge and usage in general cardiology of the Council of Cardiology Practice and the Digital Health Committee Open
The Council for Cardiology Practice of the European Society of Cardiology (ESC), in collaboration with the Digital Health Committee (DHC), undertook an electronic survey with 15 question multiple-choice questionnaire sent to 32 461 members…
View article: 2020 ESC Guidelines for the management of adult congenital heart disease
2020 ESC Guidelines for the management of adult congenital heart disease Open
info:eu-repo/semantics/published
View article: Dietary Patterns and Interventions to Alleviate Chronic Pain
Dietary Patterns and Interventions to Alleviate Chronic Pain Open
Pain is one of the main problems for modern society and medicine, being the most common symptom described by almost all patients. When pain becomes chronic, the life of the patients is dramatically affected, being associated with significa…
View article: MTHFR Gene Polymorphisms Prevalence and Cardiovascular Risk Factors Involved in Cardioembolic Stroke Type and Severity
MTHFR Gene Polymorphisms Prevalence and Cardiovascular Risk Factors Involved in Cardioembolic Stroke Type and Severity Open
Background: Cardioembolic stroke (CES), generally known as the most severe subtype of ischemic stroke, is related to many factors, including diabetes mellitus (DM), hypertension (HTN), smoking, hyperlipidemia and atrial fibrillation (AF). …
View article: Evaluation of Psychological Stress Parameters in Coronary Patients by Three Different Questionnaires as Pre-Requisite for Comprehensive Rehabilitation
Evaluation of Psychological Stress Parameters in Coronary Patients by Three Different Questionnaires as Pre-Requisite for Comprehensive Rehabilitation Open
Background: Negative psychological conditions are common in patients with cardiovascular diseases. Although depression has been scrutinized over the years in these patients, only recently has anxiety emerged as another important risk facto…
View article: The Importance of DS-14 and HADS Questionnaires in Quantifying Psychological Stress in Type 2 Diabetes Mellitus
The Importance of DS-14 and HADS Questionnaires in Quantifying Psychological Stress in Type 2 Diabetes Mellitus Open
Background and Objectives: The comorbid association between type 2 diabetes mellitus (T2DM) and a psychological profile characterized by depression and/or anxiety has been reported to increase the risk of coronary heart disease (CAD), the …
View article: Correlations between Vascular Stiffness Indicators, OPG, and 25-OH Vitamin D3 Status in Heart Failure Patients
Correlations between Vascular Stiffness Indicators, OPG, and 25-OH Vitamin D3 Status in Heart Failure Patients Open
Background and objectives: The purpose of the study is to correlate vascular calcification biomarkers osteoprotegerin (OPG) and 25-hydroxyvitamin D3 (25-OH-D3), indicators of arterial stiffness carotid-femoral pulse wave velocity (c-f PWV)…
View article: New Biomarkers in Screening Anthracycline-Induced Cardiotoxicity Only with Peripheral Blood Sampling
New Biomarkers in Screening Anthracycline-Induced Cardiotoxicity Only with Peripheral Blood Sampling Open
Because oxidative stress after administration of doxorubicin was identified as playing a central role in cardiac dysfunction, we hypothesized that the expression (or overexpression) of TLR2 and TLR4 contributes to the pathogenesis of doxor…
View article: Beneficial Effects of Multicomponent Functional Foods in Patients with Metabolic Syndrome
Beneficial Effects of Multicomponent Functional Foods in Patients with Metabolic Syndrome Open
The ANTIATERO-ALIM study was a randomized, parallel design nutritional trial testing functional food (FF) diets against the usual diet recommended in the metabolic syndrome. Functional meals included balsamic vinegar from apples and honey …