Rubayn Goh
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View article: Understanding cationic polyelectrolyte thermogels with varying charge densities toward biomaterials design
Understanding cationic polyelectrolyte thermogels with varying charge densities toward biomaterials design Open
Polyurethane thermogels are attractive materials for biomedical applications due to their reversible temperature‐controlled gelation that allows for in situ gelation at physiological temperatures. However, traditional thermogels are limite…
View article: One-Year Ultralong Intravitreal Release of Tyrosine Kinase Inhibitor from Supramolecular Temperature-Responsive Hydrogel
One-Year Ultralong Intravitreal Release of Tyrosine Kinase Inhibitor from Supramolecular Temperature-Responsive Hydrogel Open
Retinal neovascular diseases, a leading cause of blindness, can be treated with intravitreal tyrosine kinase inhibitors (TKIs). Injectable intravitreal depots capable of sustained TKI release for more than 6 months are highly desirable. Wh…
View article: Full-Thickness Chest Wall Resection and Reconstruction for Locally Invasive Phyllodes Tumors: A Systematic Review
Full-Thickness Chest Wall Resection and Reconstruction for Locally Invasive Phyllodes Tumors: A Systematic Review Open
Background/Objectives: Phyllodes tumors (PTs) are rare fibroepithelial breast neoplasms with a high propensity for local recurrence, particularly in borderline and malignant forms. Although wide local excision with negative margins is stan…
View article: Dynamic Covalent Hydrogels for Wound Healing
Dynamic Covalent Hydrogels for Wound Healing Open
Given their hydrophilic nature, hydrogels have shown great potential as wound dressing materials. However, traditional hydrogel dressing materials are static and do not adapt to dynamic wound environments, which in turn limits their wound …
View article: Predicting the need for diabetic macular oedema treatment from photographic screening in the Singapore Integrated Diabetic Retinopathy Programme (SiDRP)
Predicting the need for diabetic macular oedema treatment from photographic screening in the Singapore Integrated Diabetic Retinopathy Programme (SiDRP) Open
Objective To identify diabetic maculopathy features from photographic screening that are predictive of treatment on referral to a tertiary care centre. Methods Retrospective review of participants who underwent screening by Singapore Integ…
View article: Understanding the interplay between pH and charges for theranostic nanomaterials
Understanding the interplay between pH and charges for theranostic nanomaterials Open
Nanotechnology enables targeted theranostics by enhancing imaging and therapy. This review explores advances in pH-induced charge-switchable nanomaterials, their role in drug delivery and imaging contrast, and future directions in the fiel…
View article: Association of Abnormal Body Weight and Allergic Rhinitis—A Systematic Review and Meta‐Analysis
Association of Abnormal Body Weight and Allergic Rhinitis—A Systematic Review and Meta‐Analysis Open
Objective Allergic rhinitis (AR) is a prevalent inflammatory condition of the nasal mucosa, with significant burden worldwide. While studies have demonstrated a relationship between body mass index (BMI) and other atopic diseases, its asso…
View article: Higher risk of adverse cardiovascular outcomes in women with type 2 diabetes mellitus: an umbrella review of systematic reviews
Higher risk of adverse cardiovascular outcomes in women with type 2 diabetes mellitus: an umbrella review of systematic reviews Open
Funding Acknowledgements Type of funding sources: None. Background Previous studies have shown that females with type 2 diabetes mellitus (T2DM) may have an excess mortality risk compared to males. Furthermore, other studies have reported …
View article: The global syndemic of metabolic diseases in the young adult population: a consortium from the Global Burden of Disease 2000-2019
The global syndemic of metabolic diseases in the young adult population: a consortium from the Global Burden of Disease 2000-2019 Open
Funding Acknowledgements Type of funding sources: None. Background A large proportion of premature deaths are related to metabolic diseases in the young adult population. We examined the global trends and mortality of metabolic diseases us…
View article: Recent advances in thermogels for the management of diabetic ocular complications
Recent advances in thermogels for the management of diabetic ocular complications Open
Diabetes when left untreated can lead to various complications in the eye – at its most severe, leading to vision loss. Injectable thermogels provide a minimally-invasive platform that facilitates the treatment and recovery of these patien…
View article: Nanolattice-Forming Hybrid Collagens in Protective Shark Egg Cases
Nanolattice-Forming Hybrid Collagens in Protective Shark Egg Cases Open
Nanoscopic structural control with long-range ordering remains a profound challenge in nanomaterial fabrication. The nanoarchitectured egg cases of elasmobranchs rely on a hierarchically ordered latticework for their protective function─se…
View article: Nanolatticed Architecture Mitigates Damage in Shark Egg Cases
Nanolatticed Architecture Mitigates Damage in Shark Egg Cases Open
Structural versatility and multifunctionality of biological materials have resulted in countless bioinspired strategies seeking to emulate the properties of nature. The nanostructured egg case of swell sharks is one of the toughest permeab…
View article: Dopamine-Mediated Polymer Coating Facilitates Area-Selective Atomic Layer Deposition
Dopamine-Mediated Polymer Coating Facilitates Area-Selective Atomic Layer Deposition Open
Area-selective atomic layer deposition (ALD) has the potential to significantly improve current fabrication approaches by introducing a bottom-up process in which robust and conformal thin films are selectively deposited onto patterned sub…
View article: Evaluation of a New Point-of-Care HbA1c Assay: The Pixotest
Evaluation of a New Point-of-Care HbA1c Assay: The Pixotest Open
Glycated hemoglobin (HbA1c) is recommended by the American Diabetes Association (ADA) for the diagnosis, monitoring, and screening of diabetes/prediabetes [1].HbA1c correlates with microvascular and macrovascular complications of diabetes …
View article: Effect of Variations in Micropatterns and Surface Modulus on Marine Fouling of Engineering Polymers
Effect of Variations in Micropatterns and Surface Modulus on Marine Fouling of Engineering Polymers Open
We report on the marine fouling and fouling release effects caused by variations of surface mechanical properties and microtopography of engineering polymers. Polymeric materials were covered with hierarchical micromolded topographical pat…