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View article: Can we omit systematic biopsies in patients undergoing MRI fusion-targeted prostate biopsies?
Can we omit systematic biopsies in patients undergoing MRI fusion-targeted prostate biopsies? Open
Magnetic resonance imaging (MRI)-targeted prostate biopsy is the recommended investigation in men with suspicious lesion(s) on MRI. The role of concurrent systematic in addition to targeted biopsies is currently unclear. Using our prospect…
View article: Females with Eating Disorders and Urinary Incontinence: A Psychoanalytic Perspective
Females with Eating Disorders and Urinary Incontinence: A Psychoanalytic Perspective Open
Eating disorders (EDs) are complicated mental illnesses with significant treatment resistance and dropout rates. For successful treatment, it is important for clinicians to better understand the patients’ narrative and their lived experien…
View article: Obsessive-Compulsive Disorders and Functional Urinary Disorders: A Fortuitous Association?
Obsessive-Compulsive Disorders and Functional Urinary Disorders: A Fortuitous Association? Open
Although psychological factors are known to affect bladder and bowel control, the occurrence of functional urinary disorders in patients with psychiatric disorders has not been well-studied or described. A higher prevalence of functional l…
View article: The Role of Family Physicians in a Pandemic: A Blueprint
The Role of Family Physicians in a Pandemic: A Blueprint Open
Pandemics are a significant stress test for a country’s economic, political and health systems. An effective pandemic response demands a multi-pronged and multi-layered approach, comprising surveillance, containment, border control, as wel…
View article: Yemen’s Cholera Epidemic Is a One Health Issue
Yemen’s Cholera Epidemic Is a One Health Issue Open
Yemen has been faced with the worst cholera epidemic of modern times, with more than 1 million suspected cases and 3000 deaths at the time of writing. This problem is largely due to the longstanding civil war between pro-government forces …
View article: Clinical Role of Aspirin in Mood Disorders: A Systematic Review
Clinical Role of Aspirin in Mood Disorders: A Systematic Review Open
Worldwide, depression and bipolar disorder affect a large and growing number of people. However, current pharmacotherapy options remain limited. Despite adequate treatment, many patients continue to have subsyndromal symptoms, which predic…
View article: Escitalopram-induced liver injury: A case report and review of literature
Escitalopram-induced liver injury: A case report and review of literature Open
Clinicians should be aware of the possibility of escitalopram-induced liver injury when initiating depressed patients on antidepressant treatment. This requires extra vigilance as most patients may remain asymptomatic. Measurement of liver…
View article: Is there an association between <i>Helicobacter pylori</i> infection and irritable bowel syndrome? A meta-analysis
Is there an association between <i>Helicobacter pylori</i> infection and irritable bowel syndrome? A meta-analysis Open
Overall, current evidence does not support an association between IBS and H. pylori infection. Further rigorous and detailed studies with larger sample sizes and after H. pylori eradication therapy are warranted.
View article: A Meta-Analysis of the Utility of Preoperative Intravenous Paracetamol for Post-Caesarean Analgesia
A Meta-Analysis of the Utility of Preoperative Intravenous Paracetamol for Post-Caesarean Analgesia Open
Background and objectives: Worldwide, the number of caesarean sections performed has increased exponentially. Some studies have reported better pain control and lower postoperative requirements for opioids when intravenous (IV) paracetamol…
View article: A Systematic Review of the Role of Prebiotics and Probiotics in Autism Spectrum Disorders
A Systematic Review of the Role of Prebiotics and Probiotics in Autism Spectrum Disorders Open
Background: Autism spectrum disorder (ASD) is a complex developmental condition typically characterized by deficits in social and communicative behaviors as well as repetitive patterns of behaviors. Despite its prevalence (affecting 0.1% t…
View article: A Meta-Analysis of the Clinical Use of Curcumin for Irritable Bowel Syndrome (IBS)
A Meta-Analysis of the Clinical Use of Curcumin for Irritable Bowel Syndrome (IBS) Open
Irritable bowel syndrome (IBS) remains a prevalent and difficult-to-manage gastrointestinal condition. There is growing interest in the use of traditional medicine to manage IBS. In particular, curcumin, a biologically active phytochemical…
View article: The role of inflammation in irritable bowel syndrome (IBS)
The role of inflammation in irritable bowel syndrome (IBS) Open
Irritable bowel syndrome (IBS) is a complex, functional gastrointestinal disorder characterized by chronic abdominal pain or discomfort and altered bowel habits. Despite the global prevalence and disease burden of IBS, its underlying patho…