Ryan M. Bock
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View article: Taguchi Optimization of Additively Manufactured <scp>PEKK</scp> and Silicon Nitride Loaded <scp>PEKK</scp> for Medical Device Applications
Taguchi Optimization of Additively Manufactured <span>PEKK</span> and Silicon Nitride Loaded <span>PEKK</span> for Medical Device Applications Open
Silicon nitride (Si 3 N 4 ) is reported to exhibit antibacterial properties and support osteoblast maturation, while polyetherketoneketone (PEKK) is considered to potentially have antibacterial and osseointegrative properties while offerin…
View article: Antiviral efficacy of silicon nitride against SARS-CoV-2 and MERS-CoV: implications for PPE innovation
Antiviral efficacy of silicon nitride against SARS-CoV-2 and MERS-CoV: implications for PPE innovation Open
Medical interventions, such as masks, were a cornerstone in mitigating the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since 2019, the scientific community has increasingly focused on exploring avenues for pande…
View article: Biomechanical Evaluation of Cervical Interbody Fusion Cages for Anterior Cervical Discectomy and Fusion With Variations in Morphology: A Finite Element Analysis
Biomechanical Evaluation of Cervical Interbody Fusion Cages for Anterior Cervical Discectomy and Fusion With Variations in Morphology: A Finite Element Analysis Open
The spinal diseases commonly faced by people in the 19th century included intervertebral disc degeneration, tuberculosis and congenital defects that resulted in neurological impairment and global disability. To address these issues, cervic…
View article: Exploring the mechanical strength, antimicrobial performance, and bioactivity of 3D-printed silicon nitride-PEEK composites in cervical spinal cages
Exploring the mechanical strength, antimicrobial performance, and bioactivity of 3D-printed silicon nitride-PEEK composites in cervical spinal cages Open
In this study, our goal was to assess the suitability of a polyether-ether-ketone (PEEK) and silicon nitride (Si3N4) polymer composite for antimicrobial three-dimensional (3D)-printed cervical cages. Generic cage designs (PEEK and 15…
View article: 3D-Printed PEEK/Silicon Nitride Scaffolds with a Triply Periodic Minimal Surface Structure for Spinal Fusion Implants
3D-Printed PEEK/Silicon Nitride Scaffolds with a Triply Periodic Minimal Surface Structure for Spinal Fusion Implants Open
The issue of spine-related disorders is a global healthcare concern that requires effective solutions to restore normal spine functioning. Spinal fusion implants have become a standard approach for this purpose, making it crucial to develo…
View article: A Novel Antipathogenic Agent for Nonwoven Fabric
A Novel Antipathogenic Agent for Nonwoven Fabric Open
Medical-grade masks and N95 respirators containing non-woven fibers are designed to prevent the spread of airborne diseases. While they effectively trap respiratory droplets and aerosols, they cannot lyse entrapped pathogens. Embedded anti…
View article: Silicon Nitride Inactivates SARS-CoV-2<i>in vitro</i>
Silicon Nitride Inactivates SARS-CoV-2<i>in vitro</i> Open
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for the COVID-19 pandemic, remains viable and therefore potentially infectious on several materials. One strategy to discourage the fomite-medi…
View article: Burst Strength of BIOLOX®delta Femoral Heads and Its Dependence on Low-Temperature Environmental Degradation
Burst Strength of BIOLOX®delta Femoral Heads and Its Dependence on Low-Temperature Environmental Degradation Open
Zirconia-toughened alumina (ZTA) currently represents the bioceramic gold standard for load-bearing components in artificial hip joints. ZTA is long known for its high flexural strength and fracture toughness, both properties arising from …
View article: Bioglass functionalization of laser-patterned bioceramic surfaces and their enhanced bioactivity
Bioglass functionalization of laser-patterned bioceramic surfaces and their enhanced bioactivity Open
The surfaces of silicon nitride (β-Si3N4) and zirconia toughened alumina (ZTA) were patterned using a high-energy laser source, which operated at a wavelength of 1064 nm. The patterning procedure yielded a series regular, cylindrical cavit…
View article: Biological response of human osteosarcoma cells to Si3N4-doped Bioglasses
Biological response of human osteosarcoma cells to Si3N4-doped Bioglasses Open
In vitro and in vivo studies have recently shown that silicon nitride (Si3N4) is an osseoconductive and potential osseoinductive biomaterial. Even though the amount of bone mineral produced by Si3N4 was inferior when compared to commercial…
View article: Bioactive silicon nitride: A new therapeutic material for osteoarthropathy
Bioactive silicon nitride: A new therapeutic material for osteoarthropathy Open
While the reciprocity between bioceramics and living cells is complex, it is principally governed by the implant’s surface chemistry. Consequently, a deeper understanding of the chemical interactions of bioceramics with living tissue could…