Ryan S. Hsi
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View article: Clinical Outcomes Comparing Mini Versus Standard PCNL without Postoperative Nephrostomy Tube: A Multi-Institutional Randomized Controlled Trial from the EDGE Consortium
Clinical Outcomes Comparing Mini Versus Standard PCNL without Postoperative Nephrostomy Tube: A Multi-Institutional Randomized Controlled Trial from the EDGE Consortium Open
Results from a multi-institutional randomized controlled trial evaluating mini versus standard PCNL without postoperative nephrostomy tubes indicate no statistically significant differences in intraoperative, postoperative, or stone-free o…
View article: Comparison of 24-Hour urine parameters before and after initiation of Metformin in patients with diabetes and urolithiasis: A retrospective analysis
Comparison of 24-Hour urine parameters before and after initiation of Metformin in patients with diabetes and urolithiasis: A retrospective analysis Open
View article: Comparison of Thiazide Versus Alkali for Kidney Stone Recurrence Among Individuals With Hypocitraturia and High Urine pH
Comparison of Thiazide Versus Alkali for Kidney Stone Recurrence Among Individuals With Hypocitraturia and High Urine pH Open
Rationale & Objective: To compare symptomatic stone recurrence among individuals with low urinary citrate and high urine pH prescribed thiazides versus alkali. Study Design: Retrospective cohort study. Setting & Participants: Among Medicar…
View article: Uncertainty During Ureteroscopy: Evaluating Surgeon Consensus on In Vivo Stone Dust After Laser Lithotripsy
Uncertainty During Ureteroscopy: Evaluating Surgeon Consensus on In Vivo Stone Dust After Laser Lithotripsy Open
Surgeon assessment of stone dust quality is inconsistent, and predictive accuracy for stone-free status based on endoscopic appearance is limited. These findings underscore the need for standardized definitions and objective intraoperative…
View article: Correction to: The Effect of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists on 24-Hour Urine Parameters: A Retrospective Cohort Study
Correction to: The Effect of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists on 24-Hour Urine Parameters: A Retrospective Cohort Study Open
View article: The Effect of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists on 24-Hour Urine Parameters
The Effect of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists on 24-Hour Urine Parameters Open
Key Points In a cross-sectional study, sodium-glucose cotransporter 2 inhibitors were associated with a significant increase in urine volume and urine citrate. Glucagon-like peptide-1 receptor agonists were not associated with any signific…
View article: Large language models improve the identification of emergency department visits for symptomatic kidney stones
Large language models improve the identification of emergency department visits for symptomatic kidney stones Open
Recent advancements of large language models (LLMs) like generative pre-trained transformer 4 (GPT-4) have generated significant interest among the scientific community. Yet, the potential of these models to be utilized in clinical setting…
View article: Laboratory Abnormalities Associated with the Use of Preventive Pharmacological Therapy for Urinary Stone Disease
Laboratory Abnormalities Associated with the Use of Preventive Pharmacological Therapy for Urinary Stone Disease Open
View article: Uncertainty During Ureteroscopy: Evaluating Surgeon Consensus on in Vivo Stone Dust after Laser Lithotripsy
Uncertainty During Ureteroscopy: Evaluating Surgeon Consensus on in Vivo Stone Dust after Laser Lithotripsy Open
View article: Beneficial Impact of Follow-Up 24-Hour Urine Testing on Adherence to Pharmacological Therapy for Kidney Stone Prevention
Beneficial Impact of Follow-Up 24-Hour Urine Testing on Adherence to Pharmacological Therapy for Kidney Stone Prevention Open
Purpose: Preventive pharmacological therapy (PPT) is recommended for certain patients with urinary stone disease to reduce their recurrence risk, but they frequently do not adhere. With causal inference methods, we evaluated whether follow…
View article: Thiazide Dose, Urine Calcium, and Symptomatic Kidney Stone Events
Thiazide Dose, Urine Calcium, and Symptomatic Kidney Stone Events Open
This cohort study examines the association between thiazide dose and urine calcium reduction and correlates urine calcium changes with the occurrence of symptomatic kidney stone events.
View article: Large Language Models Improve the Identification of Emergency Department Visits for Symptomatic Kidney Stones
Large Language Models Improve the Identification of Emergency Department Visits for Symptomatic Kidney Stones Open
Background Recent advancements of large language models (LLMs) like Generative Pre-trained Transformer 4 (GPT-4) have generated significant interest among the scientific community. Yet, the potential of these models to be utilized in clini…
View article: Evaluation of Genetic Associations with Clinical Phenotypes of Kidney Stone Disease
Evaluation of Genetic Associations with Clinical Phenotypes of Kidney Stone Disease Open
We identify genetic variants linked to kidney stone disease within an electronic health record (EHR) system. These findings suggest a role for the EHR to enable a precision-medicine approach for stone disease.
View article: Preventive Pharmacological Therapy and Risk of Recurrent Urinary Stone Disease
Preventive Pharmacological Therapy and Risk of Recurrent Urinary Stone Disease Open
Background Urinary stone disease is a prevalent condition associated with a high recurrence risk. Preventive pharmacological therapy has been proposed to reduce recurrent stone episodes. However, limited evidence exists regarding its effec…
View article: Evaluation of genetic associations with clinical phenotypes of kidney stone disease
Evaluation of genetic associations with clinical phenotypes of kidney stone disease Open
Introduction and Objective We sought to replicate and discover genetic associations of kidney stone disease within a large-scale electronic health record (EHR) system. Methods We performed genome-wide association studies (GWASs) for nephro…
View article: Association of Topiramate and Zonisamide Use and Kidney Stone Risk: A Retrospective Cohort Study
Association of Topiramate and Zonisamide Use and Kidney Stone Risk: A Retrospective Cohort Study Open
View article: Comparison of Class-Specific Side Effects Across Preventative Pharmacologic Therapies for Kidney Stone Disease
Comparison of Class-Specific Side Effects Across Preventative Pharmacologic Therapies for Kidney Stone Disease Open
These data provide evidence to support clinical guidelines that recommend periodic serum testing to assess for adverse effects from preventive pharmacologic therapy.
View article: Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk
Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk Open
Importance Clinical trial data have called into question the efficacy of thiazide diuretics for the prevention of kidney stones. Objective To identify whether there is an association between genetic proxies of thiazide diuretics and the ri…
View article: Factors Affecting Holmium Laser Efficiency: Comparison of Laryngeal Mask Airway and Endotracheal Intubation During Ureteroscopy for Renal Stones
Factors Affecting Holmium Laser Efficiency: Comparison of Laryngeal Mask Airway and Endotracheal Intubation During Ureteroscopy for Renal Stones Open
Introduction: Holmium laser lithotripsy is a standard energy source used for treatment of kidney stones during flexible ureteroscopy. Efficiency of laser surgery may be affected by patient and operator characteristics or peri…
View article: PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis
PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis Open
Motivation Multimorbidity, characterized by the simultaneous occurrence of multiple diseases in an individual, is an increasing global health concern, posing substantial challenges to healthcare systems. Comprehensive understanding of dise…
View article: Machine Learning Models to Predict Kidney Stone Recurrence Using 24 Hour Urine Testing and Electronic Health Record-Derived Features
Machine Learning Models to Predict Kidney Stone Recurrence Using 24 Hour Urine Testing and Electronic Health Record-Derived Features Open
Objective To assess the accuracy of machine learning models in predicting kidney stone recurrence using variables extracted from the electronic health record (EHR). Methods We trained three separate machine learning (ML) models (least abso…
View article: Associations Between Provider Specialty and Use of Follow-up Testing Among Patients on Preventive Pharmacological Therapy for Urinary Stone Disease
Associations Between Provider Specialty and Use of Follow-up Testing Among Patients on Preventive Pharmacological Therapy for Urinary Stone Disease Open
Following initiation of preventive pharmacological therapy, adherence to guideline-recommended follow-up testing was low overall. There exist meaningful specialty-specific differences in the use of this testing.
View article: Table of Contents
Table of Contents Open
View article: Table of Contents
Table of Contents Open
View article: Feasibility of Stone Recurrence Risk Stratification Using the Recurrence of Kidney Stone (ROKS) Nomogram
Feasibility of Stone Recurrence Risk Stratification Using the Recurrence of Kidney Stone (ROKS) Nomogram Open
Purpose: We sought to assess the performance of the Recurrence of Kidney Stones nomogram for risk stratification of recurrence in a retrospective study. Materials and Methods: We performed a case-control study of 200 patients (100 with and…
View article: Enhancing sizing accuracy in ultrasound images with an alternative ADMIRE model and dynamic range considerations
Enhancing sizing accuracy in ultrasound images with an alternative ADMIRE model and dynamic range considerations Open
View article: Potential for Urolithiasis-related Research Using the Novel Medicare-Litholink Database
Potential for Urolithiasis-related Research Using the Novel Medicare-Litholink Database Open
We successfully linked Medicare claims with results from 24-hour urine collections performed by adults that were processed by Litholink. The resulting database is a unique resource for future studies on the clinical effectiveness of stone …
View article: Urinary supersaturation in a Randomized trial among Individuals with Nephrolithiasis comparing Empiric versus selective therapy (URINE): design and rationale of a clinical trial
Urinary supersaturation in a Randomized trial among Individuals with Nephrolithiasis comparing Empiric versus selective therapy (URINE): design and rationale of a clinical trial Open
View article: Table of Contents
Table of Contents Open
View article: Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs
Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs Open
Motivation Making sense of networked multivariate association patterns is vitally important to many areas of high-dimensional analysis. Unfortunately, as the data-space dimensions grow, the number of association pairs increases in O(n2); t…