Jeffrey R. Sims
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View article: Characteristics of Normal Tension Glaucoma Referrals at a Tertiary Care Center and Factors Associated with Unilateral versus Bilateral Disease
Characteristics of Normal Tension Glaucoma Referrals at a Tertiary Care Center and Factors Associated with Unilateral versus Bilateral Disease Open
Patients referred for NTG commonly present with disc changes in both eyes. Clinicians should assess for the presence of systemic diseases associated with vascular dysregulation, myopia, and a family history of glaucoma. Patients with unila…
View article: Oral Scutellarin Treatment Ameliorates Retinal Thinning and Visual Deficits in Experimental Glaucoma
Oral Scutellarin Treatment Ameliorates Retinal Thinning and Visual Deficits in Experimental Glaucoma Open
Purpose: Intraocular pressure (IOP) is currently the only modifiable risk factor for glaucoma, yet glaucoma can continue to progress despite controlled IOP. Thus, development of glaucoma neurotherapeutics remains an unmet need. Scutellarin…
View article: Role of Structural, Metabolic, and Functional <scp>MRI</scp> in Monitoring Visual System Impairment and Recovery
Role of Structural, Metabolic, and Functional <span>MRI</span> in Monitoring Visual System Impairment and Recovery Open
The visual system, consisting of the eyes and the visual pathways of the brain, receives and interprets light from the environment so that we can perceive the world around us. A wide variety of disorders can affect human vision, ranging fr…
View article: Quantitative imaging of the clearance systems in the eye and the brain
Quantitative imaging of the clearance systems in the eye and the brain Open
Debilitating neurodegenerative conditions, such as multiple sclerosis, Alzheimer’s and Parkinson’s disease, are often presented with the accumulation of metabolic byproducts in brain tissues. Recent studies also suggest linkages between oc…
View article: Functional MRI of Sensory Substitution in the Blind
Functional MRI of Sensory Substitution in the Blind Open
Visual cortex functionality in the blind has been shown to shift away from sensory networks toward task-positive networks that are involved in top-down modulation. However, how such modulation is shaped by experience and reflected behavior…