Ryan T. Phan
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View article: Serum miRNA improves the accuracy of a multivariate index assay for triage of an adnexal mass
Serum miRNA improves the accuracy of a multivariate index assay for triage of an adnexal mass Open
A multimodal assay combining miRNA with protein biomarkers, age, and menopausal status improves surgical triage of an adnexal mass.
View article: Ovarian Cancer surgical consideration is markedly improved by the neural network powered-MIA3G multivariate index assay
Ovarian Cancer surgical consideration is markedly improved by the neural network powered-MIA3G multivariate index assay Open
Background Surgery remains the main treatment option for an adnexal mass suspicious of ovarian cancer. The malignancy rate is, however, only 10–15% in women undergoing surgery. This results in a high number of unnecessary surgeries. A surv…
View article: Analysis of the Effect of Substrate Stiffness on the Efficacy of Fibroblast Growth Factor 2 and Bone Morphogenetic Protein 4 in Inducing Pro-Regenerative Astrocyte Phenotype: A Research Protocol
Analysis of the Effect of Substrate Stiffness on the Efficacy of Fibroblast Growth Factor 2 and Bone Morphogenetic Protein 4 in Inducing Pro-Regenerative Astrocyte Phenotype: A Research Protocol Open
Introduction: Astrocytes are glial cells essential for neuronal development and repair and are thus a highly promising target for regenerative therapies for neurodegenerative disease. Neurodegeneration has been connected to the degradation…
View article: Validation of a deep neural network-based algorithm supporting clinical management of adnexal mass
Validation of a deep neural network-based algorithm supporting clinical management of adnexal mass Open
Background Conservative management of adnexal mass is warranted when there is imaging-based and clinical evidence of benign characteristics. Malignancy risk is, however, a concern due to the mortality rate of ovarian cancer. Malignancy occ…
View article: Validation of A Gene Expression Signature to Measure Immune Quiescence in Kidney Transplant Recipients in the Clia Setting
Validation of A Gene Expression Signature to Measure Immune Quiescence in Kidney Transplant Recipients in the Clia Setting Open
Aim: Allograft rejection remains a major cause of graft failure in kidney transplantation. Here the authors report the validation of a non-invasive molecular diagnostic assay, AlloMap Kidney, using peripheral blood. Methods: The AlloMap Ki…
View article: Development of a New Span-Morphing Wing Core Design
Development of a New Span-Morphing Wing Core Design Open
This paper presents a new design for the core of a span-morphing unmanned aerial vehicle (UAV) wing that increases the spanwise length of the wing by fifty percent. The purpose of morphing the wingspan is to increase lift and fuel efficien…
View article: Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis
Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis Open
Our data provide evidence that proto-oncogene c-Crk is operative downstream of KRAS in NSCLC. Previously we demonstrated that Crk receives oncogenic signals from PAK1. These data in conjunction with the work of others that have specified t…
View article: Additional file 3: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens
Additional file 3: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens Open
Differentially expressed genes in CLL relative to B cells based on FPKM analysis. (XLSX 214Â kb)
View article: Additional file 7: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens
Additional file 7: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens Open
List of alternative spliced genes from MATS analysis, comparing CLL and B cell data. (XLSX 45Â kb)
View article: Additional file 8: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens
Additional file 8: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens Open
List of skipped exon events tested in CLL specimens with PCR analysis. (PPTX 119Â kb)
View article: Additional file 6: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens
Additional file 6: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens Open
Differentially expressed genes in M- and U-CLL specimens. (XLSX 78Â kb)
View article: Additional file 5: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens
Additional file 5: of Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens Open
List of genes in each functional pathway from IPA analysis. (XLSX 27Â kb)