Ryan W. Taylor
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View article: Exploring the Interplay Between Fatigue and the Oral Microbiome: A Longitudinal Approach
Exploring the Interplay Between Fatigue and the Oral Microbiome: A Longitudinal Approach Open
Fatigue is a pervasive burden for emerging medical professionals, often impacted by stress and lifestyle factors, yet insufficiently explained by these aspects alone. Considering the profound immediate and long-term consequences for physic…
View article: Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock
Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock Open
Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and plays a …
View article: Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila Open
To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele freque…
View article: Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection
Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection Open
Species conservation can be improved by knowledge of evolutionary and genetic history. Tigers are among the most charismatic of endangered species and garner significant conservation attention. However, their evolutionary history and genom…
View article: The truth about scats and dogs: Next-generation sequencing and spatial capture–recapture models offer opportunities for conservation monitoring of an endangered social canid
The truth about scats and dogs: Next-generation sequencing and spatial capture–recapture models offer opportunities for conservation monitoring of an endangered social canid Open
© This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/. Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this conten…
View article: Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data
Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data Open
Background The lion ( Panthera leo ) is one of the most popular and iconic feline species on the planet, yet in spite of its popularity, the last century has seen massive declines for lion populations worldwide. Genomic resources for endan…
View article: Long live the king: chromosome-level assembly of the lion (<i>Panthera leo</i>) using linked-read, Hi-C, and long read data
Long live the king: chromosome-level assembly of the lion (<i>Panthera leo</i>) using linked-read, Hi-C, and long read data Open
The lion ( Panthera leo ) is one of the most popular and iconic feline species on the planet, yet in spite of its popularity, the last century has seen massive declines for lion populations worldwide. Genomic resources for endangered speci…
View article: Recent evolutionary history of tigers highlights contrasting roles of genetic drift and selection
Recent evolutionary history of tigers highlights contrasting roles of genetic drift and selection Open
Formulating strategies for species conservation requires knowledge of evolutionary and genetic history. Tigers are among the most charismatic of endangered species and garner significant conservation attention. However, the evolutionary hi…
View article: Empowering conservation practice with efficient and economical genotyping from poor quality samples
Empowering conservation practice with efficient and economical genotyping from poor quality samples Open
Moderate‐ to high‐density genotyping (100 + SNPs) is widely used to determine and measure individual identity, relatedness, fitness, population structure and migration in wild populations. However, these important tools are difficult to ap…
View article: Attentive red squirrel mothers have faster-growing pups and higher lifetime reproductive success
Attentive red squirrel mothers have faster-growing pups and higher lifetime reproductive success Open
Parental investment theory predicts that observed levels of parental care afforded to offspring are set by the benefits (to offspring quality and survival) relative to the costs (to parental survival or future reproduction). Although diffi…
View article: Cost-effective assembly of the African wild dog (<i>Lycaon pictus</i>) genome using linked reads
Cost-effective assembly of the African wild dog (<i>Lycaon pictus</i>) genome using linked reads Open
Background A high-quality reference genome assembly is a valuable tool for the study of non-model organisms. Genomic techniques can provide important insights about past population sizes and local adaptation and can aid in the development …
View article: LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein
LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein Open
The cytokine leukaemia inhibitory factor (LIF) promotes self-renewal of mouse embryonic stem cells (ESCs) through activation of the transcription factor Stat3. However, the contribution of other ancillary pathways stimulated by LIF in ESCs…
View article: Empowering conservation practice with efficient and economical genotyping from poor quality samples
Empowering conservation practice with efficient and economical genotyping from poor quality samples Open
Moderate to high density genotyping (100+ SNPs) is widely used to determine and measure individual identity, relatedness, fitness, population structure and migration in wild populations. However, these important tools are difficult to appl…
View article: Entering the era of conservation genomics: Cost-effective assembly of the African wild dog genome using linked long reads
Entering the era of conservation genomics: Cost-effective assembly of the African wild dog genome using linked long reads Open
A high-quality reference genome assembly is a valuable tool for the study of non- model organisms across disciplines. Genomic techniques can provide important insights about past population sizes, local adaptation, and even aid in the deve…