Explanipedia

Circulating Tumor DNA Methylation Is a Biomarker of Poor Recurrence-free Survival in Locally-Advanced Rectal Cancer Open

Kiichi Sugimoto, Takahiro Irie, Hirotaka Momose, Shoko Kochi, Miyuki Toake , et al. · 2025

The present study demonstrates that elevated ctDNA methylation of the SOX11 gene is a biomarker for reduced RFS after curative-intent resection of LARC. Patients with high ctDNA methylation of the SOX11 gene may not be optima…

Prognostic Impact of the Postoperative Carcinoembryonic Antigen Level after Curative Resection of Locally Advanced Rectal Cancer Open

Ryoichi Tsukamoto, Kiichi Sugimoto, Yuki Ii, Takahiro Irie, Megumi Kawaguchi , et al. · 2025

Patients with post-CEA ≥2.3 ng/ml had worse long-term outcomes compared with those with post-CEA <2.3 ng/ml. Post-CEA with a cut-off of 2.3 ng/ml may be useful in determining the indication for POAC for in Stage III or high-risk Stage II c…

Experience with Laparoscopic Surgery for Rectal Obstruction Caused by Intestinal Endometriosis with a Frozen Pelvis: A Case Report Open

Hisashi Ro, Yuki Tsuchiya, Ryoichi Tsukamoto, Kumpei Honjo, Masaya Kawai , et al. · 2025

The extent of intestinal endometriosis preoperatively is difficult to determine accurately. Identifying the extent of bowel resection has a significant impact on the patient's postoperative activities of daily living. Thus, carefully obser…

Postoperative urinary dysfunction following lateral lymph node dissection for rectal cancer via minimally invasive surgery Open

Makoto Takahashi, Kazuhiro Sakamoto, Hisashi Ro, Shoko Kochi, Miyuki Toake , et al. · 2024

Influence of Temporal Muscular Activity on Neuronal Stem Cells in Rat Hippocampal Dentate Gyrus Open

Mika Honda-Sakaki, Ryoichi Tsukamoto, Takashi Iida, Yuki Ishii, Yoshihiro Komoda , et al. · 2024

The purpose of present study was to examine whether decreased temporal muscular activity after the removal of the temporalis muscle is related to the number of neural stem cells in hippocampal dentate gyrus in rats. Six rats in control gro…

Positive Circumferential Resection Margin in Rectal Cancer Is a Robust Predictor of Poor Long-term Prognosis With Clinicopathological Bias Between Groups Compensated by Propensity-score Matching Analysis Open

Kiichi Sugimoto, HIROMITSU TAKAHASHI, Yuki Yuki, Takahiro Irie, Megumi Kawaguchi , et al. · 2023

PS matching analysis demonstrated that RFS, LRFS, NLRFS, and CSS were significantly worse among patients in the CRM (+) group compared with those in the CRM (-) group. The present results indicate that CRM (+) is a robust predictor of long…

Local recurrence of submucosal invasive colorectal cancer after endoscopic submucosal dissection revealed by copy number variation Open

Yu Okazawa, Kiichi Sugimoto, Yuki Ii, Takahiro Irie, Megumi Kawaguchi , et al. · 2023

We report a case in which analysis of copy number variation revealed local recurrence of submucosal invasive colorectal cancer after curative endoscopic submucosal dissection (ESD). An 86‐year‐old man with a history of abdominoperineal res…

Richter’s Hernia with Reduction En Masse of Left Inguinal Hernia — A Case Report — Open

Kazumasa Kure, Ryoichi Tsukamoto, Yu Okazawa, Masaya Kawai, Koichiro Niwa , et al. · 2023

Surgical Treatment for Mucosal Prolapse after Intersphincteric Resection Open

Rina Takahashi, Makoto Takahashi, Yuki Ii, Megumi Kawaguchi, Hirotaka Momose , et al. · 2023

はじめに：括約筋間直腸切除術後（Intersphincteric resection：ISR）後の粘膜脱は，治療法として確立されたものはないが，当科ではDelorme手術を施行しており，その臨床経験を報告する．

Application of the Bioabsorbable Polyglycolic Acid Sheet in Colorectal Anastomosis in Animal Models Open

Shingo Kawano, Yutaka Kojima, Yuki Tsuchiya, Shunsuke Motegi, Ryoichi Tsukamoto , et al. · 2022

The bioabsorbable PGA sheet can be used for colorectal DST anastomosis in animal models and may be a valuable tool for this procedure.

Immunotherapy against esophageal primary amelanotic malignant melanoma relapse Open

Ryoichi Tsukamoto, Hiroaki Ihara, Masaru Takase, Ai Shimazu, Masahiko Takei , et al. · 2021

Melanoma is a malignant tumor derived from melanocytes. Esophageal melanomas occur infrequently, especially primary amelanotic malignant melanoma of the esophagus (PAMME), which is extremely rare. Here, we report the case of a 74-year-old …

Identification of MicroRNA 15b-3p as a Diagnostic Marker for Early Stage of Colorectal Cancer Through Comprehensive RNA Analysis Open

Ryoichi Tsukamoto, Masaki Hosoya, Midori Fukaya, Norihiko Yokoyama, Shingo Kawano , et al. · 2021

Objective Early detection is the key to treatment outcome in colorectal cancer (CRC). This study aimed to identify microRNAs (miRNAs) as a useful diagnostic marker for early-stage CRC.

Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position Open

Yuki Tsuchiya, Shinya Munakata, Ryoichi Tsukamoto, Yu Okazawa, Kosuke Mizukoshi , et al. · 2020

Background Robotic surgery for rectal cancer, which is now performed worldwide, can be associated with elevated creatine kinase levels postoperatively. In this study, we compared postoperative complications between patients undergoing robo…

Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position Open

Yuki Tsuchiya, Shinya Munakata, Ryoichi Tsukamoto, Yu Okazawa, Kosuke Mizukoshi , et al. · 2020

Background Robotic surgery for rectal cancer, which is now performed worldwide, can be associated with elevated creatine kina se levels postoperatively. In this study, we compared postoperative complications between patients undergoing rob…

Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer Open

Rina Takahashi, Kazuhiro Sakamoto, Kiichi Sugimoto, Shunsuke Motegi, Ryoichi Tsukamoto , et al. · 2019

Objective . We examined serum anti-p53 antibodies (S-p53Ab) in colorectal cancer. Specifically, we retrospectively investigated the use of S-p53Ab as a prognostic marker after surgery for colorectal cancer. Materials and Methods . The leve…

Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position Open

Yuki Tsuchiya, Shinya Munakata, Ryoichi Tsukamoto, Yu Okazawa, Kosuke Mizukoshi , et al. · 2019

Background Robotic surgery for rectal cancer, which is now performed worldwide, can be associated with elevated creatine kina se levels postoperatively. In this study, we compared postoperative complications between patient undergoing robo…

Cases of low anterior resection and ileostomy for rectal cancer that required more than 18 months for stoma closure Open

Yutaka Kojima, Kazuhiro Sakamoto, Yuichi Tomiki, Rina Takahashi, Ryoichi Tsukamoto , et al. · 2019

Laparoscopic surgery is performed worldwide, even for cases of rectal cancer close to the anus, and advances in surgical instruments and techniques have increased the number of cases for which anastomosis can be performed, even those cases…

Appendiceal Perforation due to Migration of a Dental Instrument Open

Ryoichi Tsukamoto, Shozo Miyano, Michio Machida, Toshiaki Kitabatake, Minoru Fujisawa , et al. · 2018

A 40-year-old male without any past medical history accidentally swallowed a titanium dental instrument (reamer) for root canal treatment. A cathartic was prescribed at a local hospital, and the course was observed. However, since the ream…

Study of Palliative Stoma Construction with Laparoscopic Single-incision Surgery for Locally Advanced Colorectal Cancer Open

Masaya Kawai, Ryoichi Tsukamoto, Shinya Munakata, Kiichi Sugimoto, Hirohiko Kamiyama , et al. · 2018

【目的】緩和的な人工肛門造設術では,低侵襲性とQOLの維持が重要となる.当科で経験した症例をretrospectiveに解析し,単孔式腹腔鏡下手術の有用性について検討した.

Case of idiopathic and complete appendiceal intussusception Open

Ryoichi Tsukamoto, Kazuhiro Sakamoto, Kumpei Honjo, Koichiro Niwa, Kiichi Sugimoto , et al. · 2017

Appendiceal intussusception is a rare disease in which the appendix invaginates into the cecum. It is often caused by organic diseases. The present case involved an appendiceal intussusception without an organic disease, and laparoscopic r…

A patient with paraganglioma arising from the mesocolon Open

Ryoichi Tsukamoto, Shunsuke Motegi, Kumpei Honjo, Hisashi Ro, Shun Ishiyama , et al. · 2017

Minimally Invasive Surgery for Colorectal Cancer Open

Kazuhiro Sakamoto, Ryoichi Tsukamoto, Shingo Kawano, Masaya Kawai, Koichiro Niwa , et al. · 2017

Laparoscopic colectomy was first used for the treatment of colorectal cancer early in the 1990s, before spreading rapidly throughout the world. In comparison with open surgery, laparoscopic colectomy has the advantages of smaller incision,…

A Case of Goblet Cell Carcinoid of Appendix which the Laparoscopic Evaluation Worked for Treatment: A Review of the 126 Cases in Japan Open

Shun Ishiyama, Ryoichi Tsukamoto, Kazumasa Kure, Rina Takahashi, Kiichi Sugimoto , et al. · 2017

虫垂杯細胞カルチノイド（goblet cell carcinoid，以下GCC）は虫垂に発生する比較的稀な腫瘍である．今回，腹腔鏡観察が治療に有効であると考えられた虫垂GCCの症例を経験したので報告する．症例は45歳，男性．繰り返す腸閉塞の診断で手術となった．腹腔鏡観察で，白色の硬結，壁肥厚を伴う虫垂と，回腸末端部を起点とする回腸の拡張を認めたため，虫垂悪性腫瘍の回盲部浸潤と判断し，腹腔鏡下回盲部切除術（D2郭清）を施行した．病理組織検査で虫垂GCCの回盲部浸潤と診断された…

A case of internal hemorrhoid with diffuse cavernous hemangioma of the colon treated with endoscopic sclerotherapy with ALTA Open

Jun Aoki, Ryoichi Tsukamoto, Ryosuke Ichikawa, Kazumasa Kure, Kumpei Honjo , et al. · 2016

A male patient in his 20s consulted a nearby clinic because of physical weariness and melena on October 2010. He was referred to our hospital for the treatment of internal hemorrhoid and severe anemia. We performed colonoscopy for colorect…

One Case of a Inguinal Herunia Complicating Undescended Testis Taking a Unique Pathway Open

Kumpei Honjo, Ryoichi Tsukamoto, Jun Aoki, Rina Takahashi, Shinya Munakata , et al. · 2016

症例は60歳台，男性．検診で貧血を指摘され，大腸内視鏡検査でS状結腸癌と診断され，紹介受診となった．腹部所見で右下腹部から側腹部に拡がる30cm大の巨大な腫瘤を認めた．腹部CT検査で，右鼠径部から側腹部に小腸の脱出がみられ，右鼠径ヘルニアと診断した．また，右鼠径部に精巣が同定され，右停留精巣と診断した．以上より，S状結腸癌に対するS状結腸切除術と同時に右鼠径ヘルニア修復術，右精巣摘出術を施行した．腹腔鏡所見では右外鼠径ヘルニアで，小腸がヘルニア門から脱出していた．まず，小腸…

Ryoichi Tsukamoto YOU? Author Swipe