Ryosuke Gabata
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View article: Impact of aging on hepatic reserve after preoperative portal vein embolization in hepatectomy for perihilar cholangiocarcinoma
Impact of aging on hepatic reserve after preoperative portal vein embolization in hepatectomy for perihilar cholangiocarcinoma Open
This study showed aging suppresses hepatic reserve improvement in the FRL, particularly in ICG clearance after PVE in PHCC cases.
View article: Predictors of portal vein thrombosis after simultaneous hepatectomy and splenectomy: A single-center retrospective study
Predictors of portal vein thrombosis after simultaneous hepatectomy and splenectomy: A single-center retrospective study Open
Our results suggest that splenic vein dilatation is an independent risk factor for PVT after simultaneous HS, and that PVT after HS occurs more frequently in the intrahepatic portal vein. After HS for cases with dilated splenic veins, we s…
View article: Clinicopathological features of cholangiolocarcinoma and impact of tumor heterogeneity on prognosis: A single institution retrospective study
Clinicopathological features of cholangiolocarcinoma and impact of tumor heterogeneity on prognosis: A single institution retrospective study Open
Cholangiolocarcinoma (CLC) is an extremely rare tumor classified as a subtype of small duct-type intrahepatic cholangiocarcinoma (iCCA). There are few detailed reports on CLC and the prognostic impact of tumor heterogeneity is not clear. B…
View article: Clinicopathological features of cholangiolocarcinoma and impact of tumor heterogeneity on prognosis: A retrospective study in a single institution
Clinicopathological features of cholangiolocarcinoma and impact of tumor heterogeneity on prognosis: A retrospective study in a single institution Open
Background: Cholangiolocarcinoma (CLC) is an extremely rare tumor classified as a subtype of small duct-type intrahepatic cholangiocarcinoma (iCCA). There are few detailed reports on CLC, and the prognostic impact of tumor heterogeneity is…
View article: Case report: therapeutic monitoring of vancomycin in an acute liver failure patient with anuria under high-flow continuous hemodiafiltration
Case report: therapeutic monitoring of vancomycin in an acute liver failure patient with anuria under high-flow continuous hemodiafiltration Open
Background High-flow continuous hemodiafiltration (HF-CHDF) combines diffusive and convective solute removal and is employed for artificial liver adjuvant therapy. However, there is no report on dosage planning of vancomycin (VCM) in patie…
View article: Education of microsurgical technique for young surgeons by International Society for Experimental Microsurgery West Japan and future prospects
Education of microsurgical technique for young surgeons by International Society for Experimental Microsurgery West Japan and future prospects Open
The need for microscopic vascular anastomosis has increased in the field of gastrointestinal surgery. Herein we report the activities for microsurgical training by ISEM West Japan.Since 2015, we have held the Hands-on seminar twice a year …
View article: Micro- and macro-borderless surgery using a newly developed high-resolution (4K) three-dimensional video system
Micro- and macro-borderless surgery using a newly developed high-resolution (4K) three-dimensional video system Open
Objective Microsurgery using conventional optical microscopes or surgical loupes features a limited field of view and imposes a serious strain on surgeons especially during long surgeries. Here we advocate the micro- and macro-borderless s…
View article: A phase I study of preoperative (neoadjuvant) chemotherapy with gemcitabine plus nab‑paclitaxel for resectable pancreatic cancer
A phase I study of preoperative (neoadjuvant) chemotherapy with gemcitabine plus nab‑paclitaxel for resectable pancreatic cancer Open
Neoadjuvant chemotherapy (NAC) has become a standard treatment for borderline resectable pancreatic ductal adenocarcinoma (PDAC). The present study examined the maximum tolerated dose of NAC with gemcitabine plus nab-paclitaxel (GnP) in pa…
View article: Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against β-Catenin-activated Hepatocellular Carcinoma
Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against β-Catenin-activated Hepatocellular Carcinoma Open
PRI-724(C-82) may be a novel drug for β-catenin-activated HCC therapy.
View article: Analysis of 5 patients with isolated lung metastases after resection of pancreatic cancer
Analysis of 5 patients with isolated lung metastases after resection of pancreatic cancer Open
術後再発をきたした膵癌は一般的には予後不良だが,肺転移単独再発は比較的予後が良好な場合がある.2006~2017年に当科で原発巣切除を行った浸潤性膵管癌112例のうち,術後初回に肺転移単独再発を認めたのは5例で全例男性であった.5例のうち3例に肺転移に対する切除が行われ,切除を行わなかった2例の内訳は1例が切除不能多発肺転移症例,もう1例は呼吸機能低下による切除不能症例であった.5例とも術前補助化学療法が施行されており,術後補助化学療法は4例に行われていた.病理学的には4例…
View article: Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats
Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats Open
BACKGROUND Severe pericentral zone (zone 3)-based liver injury (LI) may become intractable, with allograft dysfunction after liver transplantation. The phosphodiesterase-3 inhibitor, milrinone, has been reported to attenuate hepatic ischem…
View article: CD38, CD157, and RAGE as Molecular Determinants for Social Behavior
CD38, CD157, and RAGE as Molecular Determinants for Social Behavior Open
Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knocko…
View article: Impact of Extravasated Platelet Activation and Podoplanin-positive Cancer-associated Fibroblasts in Pancreatic Cancer Stroma
Impact of Extravasated Platelet Activation and Podoplanin-positive Cancer-associated Fibroblasts in Pancreatic Cancer Stroma Open
There is a significant association between EPA and PDPN-positive CAFs in pancreatic cancer stroma. Our data suggest that the GnP regimen decreases EPA through PDPN-positive CAF depletion.
View article: Safety of artificial pancreas in hepato-biliary-pancreatic surgery: A prospective study
Safety of artificial pancreas in hepato-biliary-pancreatic surgery: A prospective study Open
The AP was safe during IIT, with no hypoglycemia observed perioperatively in patients who underwent highly invasive HBPS. Further studies are required to address the efficacy of AP with IIT in highly invasive situations.
View article: Induction of Artificial Pancreas in Liver Transplant Recipients: Preliminary Experience with an Insightful Message
Induction of Artificial Pancreas in Liver Transplant Recipients: Preliminary Experience with an Insightful Message Open
BACKGROUND We investigated the impact of using an artificial pancreas for glycemic control in liver transplant recipients. MATERIAL AND METHODS Between January 2014 and December 2016, glycemic control using an artificial pancreas was perfo…
View article: Congestive Preconditioning by Portal Venous Clamping: A Novel Preventive Concept for Small Intestinal Congestive Re-Outflow Injury
Congestive Preconditioning by Portal Venous Clamping: A Novel Preventive Concept for Small Intestinal Congestive Re-Outflow Injury Open
BACKGROUND Congestion of the small intestine, which induces mucosal damage via apoptosis, is a common pathophysiological change in hepato-biliary-pancreatic surgery, including liver transplantation. Small intestinal mucosal damage can trig…